| Entry |
|
|---|
| Name |
Goserelin acetate (JAN/USP);
Zoladex (TN) |
|---|
| Product |
|
|---|
| Formula |
C59H84N18O14. (C2H4O2)x
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Hormonal agent
DG01494 Gonadotropin-releasing hormone receptor agonist
|
|---|
| Remark |
| Therapeutic category: | 2499 |
| Product (DG00731): | D00573<JP/US> |
|
|---|
| Efficacy |
Antineoplastic, Gonadotropin-releasing hormone receptor agonist |
|---|
| Disease |
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L02 ENDOCRINE THERAPY
L02A HORMONES AND RELATED AGENTS
L02AE Gonadotropin releasing hormone analogues
L02AE03 Goserelin
D00573 Goserelin acetate (JAN/USP) <JP/US>
USP drug classification [BR:br08302]
Antineoplastics
Antineoplastics, Other
Goserelin
D00573 Goserelin acetate (JAN/USP)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
24 Hormones
249 Miscellaneous
2499 Others
D00573 Goserelin acetate (JAN/USP)
Drug groups [BR:br08330]
Hormonal agent
DG01494 Gonadotropin-releasing hormone receptor agonist
DG00731 Goserelin
D00573 Goserelin acetate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Gonadotropin-releasing hormone
GNRHR
D00573 Goserelin acetate (JAN/USP) <JP/US>
Drug groups [BR:br08330]
Hormonal agent
DG01494 Gonadotropin-releasing hormone receptor agonist
DG00731 Goserelin
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 95
1 C6a C 43.0248 -27.7517
2 O6a O 44.2380 -28.4521
3 C1a C 41.8118 -28.4521
4 O6a O 43.0248 -26.3510
5 C8y C 20.5100 -20.2300
6 C8y C 21.0000 -18.9000
7 C1b C 19.3200 -20.9300
8 C8x C 21.7000 -21.0700
9 C8y C 22.4000 -18.9000
10 C8x C 20.3000 -17.6400
11 C1c C 19.3200 -22.3300
12 N4x N 22.8200 -20.2300
13 C8x C 23.1000 -17.6400
14 C8x C 21.0700 -16.4500
15 N1b N 18.1300 -23.0300
16 C5a C 20.5100 -23.0300
17 C8x C 22.4000 -16.4500
18 C5a C 16.8700 -22.3300
19 N1b N 21.7700 -22.3300
20 O5a O 20.5100 -24.4300
21 C1c C 15.6800 -23.0300
22 O5a O 16.8700 -20.9300
23 C1c C 22.9600 -23.0300
24 C1b C 15.6800 -24.4300
25 N1b N 14.4900 -22.3300
26 C5a C 24.2200 -22.3300
27 C1b C 22.9600 -24.4300
28 C8y C 16.8700 -25.0600
29 C5a C 13.3000 -23.0300
30 N1b N 25.4100 -23.0300
31 O5a O 24.2200 -20.9300
32 O1a O 24.2200 -25.0600
33 C8x C 18.2700 -24.7100
34 N5x N 16.8700 -26.5300
35 C1y C 12.0400 -22.3300
36 O5a O 13.3000 -24.4300
37 C1c C 26.6000 -22.3300
38 N4x N 18.9700 -25.9000
39 C8x C 18.1300 -27.0200
40 C1x C 10.7100 -22.7500
41 N1x N 12.0400 -20.9300
42 C1b C 26.6000 -20.9300
43 C5a C 27.7900 -23.0300
44 C1x C 9.8700 -21.6300
45 C5x C 10.7100 -20.5100
46 C8y C 27.7900 -20.2300
47 N1b N 29.0500 -22.3300
48 O5a O 27.7900 -24.4300
49 O5x O 10.2900 -19.1800
50 C8x C 29.0500 -20.9300
51 C8x C 27.7900 -18.8300
52 C1c C 30.2400 -23.0300
53 C8x C 30.2400 -20.2300
54 C8x C 29.0500 -18.1300
55 C5a C 31.5000 -22.3300
56 C1b C 30.2400 -24.4300
57 C8y C 30.2400 -18.8300
58 N1b N 32.6900 -23.0300
59 O5a O 31.5000 -20.9300
60 O2a O 29.0500 -25.0600
61 O1a O 31.4300 -18.1300
62 C1c C 33.8800 -22.3300
63 C1d C 29.0500 -26.5300
64 C5a C 35.0700 -23.0300
65 C1b C 33.8800 -20.9300
66 C1a C 29.0500 -28.0000
67 C1a C 30.4500 -26.5300
68 C1a C 27.7200 -26.5300
69 N1b N 36.2600 -22.3300
70 O5a O 35.0700 -24.4300
71 C1c C 35.0700 -20.2300
72 C1c C 37.5200 -23.0300
73 C1a C 35.0700 -18.8300
74 C1a C 36.2600 -20.9300
75 C5a C 38.7800 -22.3300
76 C1b C 37.5200 -24.4300
77 N1y N 39.9700 -23.0300
78 O5a O 38.7800 -20.9300
79 C1b C 36.2600 -25.0600
80 C1y C 41.3700 -23.0300
81 C1x C 39.5500 -24.3600
82 C1b C 36.2600 -26.5300
83 C1x C 41.7900 -24.2900
84 C5a C 42.5600 -22.2600
85 C1x C 40.6700 -25.1300
86 N1b N 35.0700 -27.2300
87 N1b N 43.7500 -22.9600
88 O5a O 42.5600 -20.9300
89 C2c C 33.8800 -26.5300
90 N1a N 32.6900 -27.2300
91 N2a N 33.8800 -25.0600
92 N1b N 45.0100 -22.2600
93 C5a C 46.2000 -22.9600
94 N1a N 47.3900 -22.2600
95 O5a O 46.2000 -24.3600
BOND 99
1 1 2 1
2 1 3 1
3 1 4 2
4 5 6 1
5 5 7 1
6 5 8 2
7 6 9 2
8 6 10 1
9 7 11 1
10 8 12 1
11 9 13 1
12 10 14 2
13 11 15 1
14 11 16 1 #Up
15 13 17 2
16 15 18 1
17 16 19 1
18 16 20 2
19 18 21 1
20 18 22 2
21 23 19 1 #Down
22 21 24 1 #Down
23 21 25 1
24 23 26 1
25 23 27 1
26 24 28 1
27 25 29 1
28 26 30 1
29 26 31 2
30 27 32 1
31 28 33 2
32 28 34 1
33 35 29 1 #Down
34 29 36 2
35 30 37 1
36 33 38 1
37 34 39 2
38 35 40 1
39 35 41 1
40 37 42 1 #Up
41 37 43 1
42 40 44 1
43 41 45 1
44 42 46 1
45 43 47 1
46 43 48 2
47 45 49 2
48 46 50 2
49 46 51 1
50 47 52 1
51 50 53 1
52 51 54 2
53 52 55 1
54 52 56 1 #Up
55 53 57 2
56 55 58 1
57 55 59 2
58 56 60 1
59 57 61 1
60 58 62 1
61 60 63 1
62 62 64 1
63 62 65 1 #Up
64 63 66 1
65 63 67 1
66 63 68 1
67 64 69 1
68 64 70 2
69 65 71 1
70 69 72 1
71 71 73 1
72 71 74 1
73 72 75 1
74 72 76 1 #Down
75 75 77 1
76 75 78 2
77 76 79 1
78 77 80 1
79 77 81 1
80 79 82 1
81 80 83 1
82 80 84 1 #Down
83 81 85 1
84 82 86 1
85 84 87 1
86 84 88 2
87 86 89 1
88 89 90 1
89 89 91 2
90 9 12 1
91 14 17 1
92 38 39 1
93 44 45 1
94 54 57 1
95 83 85 1
96 87 92 1
97 92 93 1
98 93 94 1
99 93 95 2
BRACKET 1 39.8300 -29.2600 39.8300 -25.5500
1 45.7100 -25.5500 45.7100 -29.2600
1 x
ORIGINAL 1 1 2 3 4
REPEAT 1
|
|---|
