| Entry |
|
|---|
| Name |
Foscarnet sodium (USP/INN);
Foscavir (TN) |
|---|
| Formula |
CO5P. 3Na
|
|---|
| Exact mass |
191.9176
|
|---|
| Mol weight |
191.9508
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antiviral
DG01937 Anti-cytomegalovirus agent
|
|---|
| Remark |
| Product (DG00651): | D02267<JP/US> |
|
|---|
| Efficacy |
Antiviral, DNA polymerase inhibitor |
|---|
| Disease |
|
|---|
| Comment |
Phosphonic acid derivative
|
|---|
| Target |
HCMV DNA polymerase [KO: K18964] |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J05 ANTIVIRALS FOR SYSTEMIC USE
J05A DIRECT ACTING ANTIVIRALS
J05AD Phosphonic acid derivatives
J05AD01 Foscarnet
D00579 Foscarnet sodium (USP/INN)
Drug groups [BR:br08330]
Antiviral
DG01937 Anti-cytomegalovirus agent
DG00651 Foscarnet
D00579 Foscarnet sodium
Antimicrobials [BR:br08307]
Antivirals
Genome replication inhibitor
Herpesvirus DNA polymerase inhibitor
D00579 Foscarnet sodium (USP/INN)
Drug groups [BR:br08330]
Antiviral
DG01937 Anti-cytomegalovirus agent
DG00651 Foscarnet
Antimicrobials abbreviations [BR:br08327]
Antivirals
Genome replication inhibitor
Herpesvirus DNA polymerase inhibitor
DG00651 Foscarnet
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 10
1 Z Na 26.5842 -23.6738 #+
2 Z Na 30.8880 -22.3875 #+
3 Z Na 23.9722 -21.1394 #+
4 P1b P 27.2300 -21.1400
5 C6a C 28.6300 -21.1400
6 O1c O 27.2300 -22.5400 #-
7 O1c O 25.8300 -21.1400 #-
8 O1c O 27.2300 -19.7400
9 O6a O 29.3300 -22.4000 #-
10 O6a O 29.3300 -19.9500
BOND 6
1 4 6 1
2 4 7 1
3 4 8 2
4 5 9 1
5 4 5 1
6 5 10 2
|
|---|
