| Entry |
|
|---|
| Name |
Trimetaphan camsilate (JAN/INN);
Trimetaphan camsylate;
Arfonad (TN) |
|---|
| Formula |
C22H25N2OS. C10H15O4S
|
|---|
| Exact mass |
596.2379
|
|---|
| Mol weight |
596.8004
|
|---|
| Structure |
|
|---|
| Class |
Cardiovascular agent
DG01695 Ganglion-blocking antiadrenergic
|
|---|
| Remark |
|
|---|
| Efficacy |
Antihypertensive |
|---|
| Comment |
Sulfonium derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C02 ANTIHYPERTENSIVES
C02B ANTIADRENERGIC AGENTS, GANGLION-BLOCKING
C02BA Sulfonium derivatives
C02BA01 Trimetaphan
D00612 Trimetaphan camsilate (JAN/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01695 Ganglion-blocking antiadrenergic
DG00251 Trimetaphan
D00612 Trimetaphan camsilate
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Acetylcholine (nicotinic)
CHRNA10
D00612 Trimetaphan camsilate (JAN/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01695 Ganglion-blocking antiadrenergic
DG00251 Trimetaphan
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 41
1 C1y C 19.2886 -16.3960
2 C1y C 20.0479 -15.2220
3 C1y C 17.9334 -16.0339
4 N1y N 20.1647 -17.4826
5 N1y N 21.4673 -15.5899
6 C1x C 19.1660 -14.1355
7 S2x S 17.9333 -14.6262 #+
8 C1x C 16.6191 -16.5304
9 C5x C 21.4674 -16.9861
10 C1b C 20.1473 -18.8785
11 C1b C 22.6122 -14.8949
12 C1x C 16.5081 -14.2581
13 C1x C 15.7371 -15.4381
14 O5x O 22.6415 -17.7453
15 C8y C 21.3505 -19.5912
16 C8y C 23.8213 -15.5958
17 C8x C 21.3331 -20.9814
18 C8x C 22.5654 -18.8960
19 C8x C 23.8213 -16.9918
20 C8x C 25.0305 -14.9006
21 C8x C 22.5363 -21.6941
22 C8x C 23.7688 -19.6086
23 C8x C 25.0305 -17.6928
24 C8x C 26.2396 -15.5958
25 C8x C 23.7571 -21.0048
26 C8x C 26.2396 -16.9918
27 C1z C 32.5073 -18.2243
28 C1z C 31.9115 -16.1157
29 C5x C 33.6463 -18.7910
30 C1x C 31.2864 -18.8318
31 C1b C 31.8707 -19.5211
32 C1y C 32.8520 -17.0853
33 C1a C 32.4197 -14.7488
34 C1a C 30.8543 -15.3212
35 C1x C 34.1137 -17.8097
36 O5x O 34.0961 -20.1285
37 C1x C 31.8590 -17.7920
38 S4a S 30.4921 -19.5270
39 O1d O 29.8671 -20.7653
40 O1d O 29.7385 -18.3761
41 O1d O 31.5260 -20.6601 #-
BOND 46
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 3 8 1
8 4 9 1
9 4 10 1
10 5 11 1
11 7 12 1
12 8 13 1
13 9 14 2
14 10 15 1
15 11 16 1
16 15 17 2
17 15 18 1
18 16 19 2
19 16 20 1
20 17 21 1
21 18 22 2
22 19 23 1
23 20 24 2
24 21 25 2
25 23 26 2
26 5 9 1
27 6 7 1
28 12 13 1
29 22 25 1
30 24 26 1
31 27 28 1
32 27 29 1
33 27 30 1
34 27 31 1
35 28 32 1
36 28 33 1
37 28 34 1
38 29 35 1
39 29 36 2
40 30 37 1
41 31 38 1
42 38 39 2
43 38 40 2
44 38 41 1
45 32 35 1
46 32 37 1
|
|---|
