 | | DRUG: Buspirone hydrochloride | |
| Entry |
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| Name |
Buspirone hydrochloride (USP);
Buspar (TN) |
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| Product |
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| Generic |
BUSPIRONE HCL (Advagen Pharma), BUSPIRONE HCL (Amneal Pharmaceuticals NY LLC), BUSPIRONE HCL (Bryant Ranch Prepack), BUSPIRONE HCL (Direct Rx), BUSPIRONE HCL (Direct_Rx), BUSPIRONE HCL (Direct_Rx), BUSPIRONE HCL (Proficient Rx LP), BUSPIRONE HCL (Proficient Rx LP), BUSPIRONE HCL (Quality Care Products), BUSPIRONE HCL (REMEDYREPACK), BUSPIRONE HCL (REMEDYREPACK), BUSPIRONE HYDROCHLORIDE (A-S Medication Solutions), BUSPIRONE HYDROCHLORIDE (A-S Medication Solutions), BUSPIRONE HYDROCHLORIDE (A-S Medication Solutions), BUSPIRONE HYDROCHLORIDE (A-S Medication Solutions), BUSPIRONE HYDROCHLORIDE (A-S Medication Solutions), BUSPIRONE HYDROCHLORIDE (A-S Medication Solutions), BUSPIRONE HYDROCHLORIDE (A-S Medication Solutions), BUSPIRONE HYDROCHLORIDE (A-S Medication Solutions), BUSPIRONE HYDROCHLORIDE (A-S Medication Solutions), BUSPIRONE HYDROCHLORIDE (A-S Medication Solutions), BUSPIRONE HYDROCHLORIDE (A-S Medication Solutions), BUSPIRONE HYDROCHLORIDE (A-S Medication Solutions), BUSPIRONE HYDROCHLORIDE (A-S Medication Solutions), BUSPIRONE HYDROCHLORIDE (Accord Healthcare), BUSPIRONE HYDROCHLORIDE (Advanced Rx Pharmacy of Tennessee), BUSPIRONE HYDROCHLORIDE (Advanced Rx Pharmacy of Tennessee), BUSPIRONE HYDROCHLORIDE (American Health Packaging), BUSPIRONE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUSPIRONE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUSPIRONE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUSPIRONE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUSPIRONE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUSPIRONE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUSPIRONE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUSPIRONE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUSPIRONE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUSPIRONE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUSPIRONE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUSPIRONE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUSPIRONE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUSPIRONE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUSPIRONE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUSPIRONE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUSPIRONE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUSPIRONE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUSPIRONE HYDROCHLORIDE (Aurobindo Pharma Limited), BUSPIRONE HYDROCHLORIDE (AvPAK), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Bryant Ranch Prepack), BUSPIRONE HYDROCHLORIDE (Cardinal Health 107), BUSPIRONE HYDROCHLORIDE (Cardinal Health 107), BUSPIRONE HYDROCHLORIDE (Cardinal Health 107), BUSPIRONE HYDROCHLORIDE (DIRECT RX), BUSPIRONE HYDROCHLORIDE (Denton Pharma), BUSPIRONE HYDROCHLORIDE (Direct Rx), BUSPIRONE HYDROCHLORIDE (Direct_Rx), BUSPIRONE HYDROCHLORIDE (EPIC PHARMA), BUSPIRONE HYDROCHLORIDE (Epic Pharma), BUSPIRONE HYDROCHLORIDE (Golden State Medical Supply), BUSPIRONE HYDROCHLORIDE (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), BUSPIRONE HYDROCHLORIDE (Major Pharmaceuticals), BUSPIRONE HYDROCHLORIDE (Major Pharmaceuticals), BUSPIRONE HYDROCHLORIDE (Mylan Institutional), BUSPIRONE HYDROCHLORIDE (Mylan Pharmaceuticals), BUSPIRONE HYDROCHLORIDE (NCS HealthCare of KY), BUSPIRONE HYDROCHLORIDE (NCS HealthCare of KY), BUSPIRONE HYDROCHLORIDE (Nivagen Pharmaceuticals), BUSPIRONE HYDROCHLORIDE (Northwind Pharmaceuticals), BUSPIRONE HYDROCHLORIDE (Northwind Pharmaceuticals), BUSPIRONE HYDROCHLORIDE (Northwind Pharmaceuticals), BUSPIRONE HYDROCHLORIDE (NuCare Pharmaceuticals), BUSPIRONE HYDROCHLORIDE (NuCare Pharmaceuticals), BUSPIRONE HYDROCHLORIDE (NuCare Pharmaceuticals), BUSPIRONE HYDROCHLORIDE (Oxford Pharmaceuticals), BUSPIRONE HYDROCHLORIDE (PD-Rx Pharmaceuticals), BUSPIRONE HYDROCHLORIDE (PD-Rx Pharmaceuticals), BUSPIRONE HYDROCHLORIDE (PD-Rx Pharmaceuticals), BUSPIRONE HYDROCHLORIDE (PD-Rx Pharmaceuticals), BUSPIRONE HYDROCHLORIDE (Preferred Pharmaceuticals), BUSPIRONE HYDROCHLORIDE (Preferred Pharmaceuticals), BUSPIRONE HYDROCHLORIDE (Preferred Pharmaceuticals), BUSPIRONE HYDROCHLORIDE (Proficient Rx LP), BUSPIRONE HYDROCHLORIDE (Proficient Rx LP), BUSPIRONE HYDROCHLORIDE (Proficient Rx LP), BUSPIRONE HYDROCHLORIDE (Proficient Rx LP), BUSPIRONE HYDROCHLORIDE (Proficient Rx LP), BUSPIRONE HYDROCHLORIDE (Proficient Rx LP), BUSPIRONE HYDROCHLORIDE (Proficient Rx LP), BUSPIRONE HYDROCHLORIDE (Quality Care Products), BUSPIRONE HYDROCHLORIDE (Quality Care Products), BUSPIRONE HYDROCHLORIDE (Quality Care Products), BUSPIRONE HYDROCHLORIDE (REMEDYREPACK), BUSPIRONE HYDROCHLORIDE (REMEDYREPACK), BUSPIRONE HYDROCHLORIDE (REMEDYREPACK), BUSPIRONE HYDROCHLORIDE (REMEDYREPACK), BUSPIRONE HYDROCHLORIDE (REMEDYREPACK), BUSPIRONE HYDROCHLORIDE (REMEDYREPACK), BUSPIRONE HYDROCHLORIDE (REMEDYREPACK), BUSPIRONE HYDROCHLORIDE (REMEDYREPACK), BUSPIRONE HYDROCHLORIDE (REMEDYREPACK), BUSPIRONE HYDROCHLORIDE (REMEDYREPACK), BUSPIRONE HYDROCHLORIDE (REMEDYREPACK), BUSPIRONE HYDROCHLORIDE (REMEDYREPACK), BUSPIRONE HYDROCHLORIDE (REMEDYREPACK), BUSPIRONE HYDROCHLORIDE (REMEDYREPACK), BUSPIRONE HYDROCHLORIDE (REMEDYREPACK), BUSPIRONE HYDROCHLORIDE (REMEDYREPACK), BUSPIRONE HYDROCHLORIDE (REMEDYREPACK), BUSPIRONE HYDROCHLORIDE (REMEDYREPACK), BUSPIRONE HYDROCHLORIDE (REMEDYREPACK), BUSPIRONE HYDROCHLORIDE (REMEDYREPACK), BUSPIRONE HYDROCHLORIDE (REMEDYREPACK), BUSPIRONE HYDROCHLORIDE (REMEDYREPACK), BUSPIRONE HYDROCHLORIDE (REMEDYREPACK), BUSPIRONE HYDROCHLORIDE (REMEDYREPACK), BUSPIRONE HYDROCHLORIDE (RPK Pharmaceuticals), BUSPIRONE HYDROCHLORIDE (RPK Pharmaceuticals), BUSPIRONE HYDROCHLORIDE (RPK Pharmaceuticals), BUSPIRONE HYDROCHLORIDE (Strides Pharma Science Limited), BUSPIRONE HYDROCHLORIDE (Strides Pharma), BUSPIRONE HYDROCHLORIDE (Teva Pharmaceuticals USA), BUSPIRONE HYDROCHLORIDE (Unichem Pharmaceuticals (USA)), BUSPIRONE HYDROCHLORIDE (Yiling Pharmaceutical), BUSPIRONE HYDROCHLORIDE (Zydus Lifesciences Limited), BUSPIRONE HYDROCHLORIDE (Zydus Pharmaceuticals USA) |
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| Formula |
C21H31N5O2. HCl
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| Exact mass |
421.2245
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| Mol weight |
421.9641
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| Structure |
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| Simcomp |
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| Class |
Neuropsychiatric agent
DG01483 5-HT1A-receptor agonist
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| Remark |
| Product (DG00913): | D00702<US> |
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| Efficacy |
Antianxiety, Minor tranquilizer, Serotonin 5-HT1A receptor agonist |
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| Disease |
Generalized anxiety disorder [DS: H01662] |
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| Comment |
Buspirone derivative
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Interaction |
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| Structure map |
| map07211 | Serotonin receptor agonists/antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05B ANXIOLYTICS
N05BE Azaspirodecanedione derivatives
N05BE01 Buspirone
D00702 Buspirone hydrochloride (USP) <US>
USP drug classification [BR:br08302]
Anxiolytics
Anxiolytics, Other
Buspirone
D00702 Buspirone hydrochloride (USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01483 5-HT1A-receptor agonist
DG00913 Buspirone
D00702 Buspirone hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D00702 Buspirone hydrochloride (USP) <US>
Serotonin
HTR1A
D00702 Buspirone hydrochloride (USP) <US>
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01483 5-HT1A-receptor agonist
DG00913 Buspirone
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| Other DBs |
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| KCF data |
ATOM 29
1 C1z C 30.6703 -12.8797
2 C1x C 29.4326 -12.1783
3 C1x C 30.6740 -14.2783
4 C5x C 28.2471 -12.9204
5 C5x C 29.4419 -15.0222
6 N1y N 28.2509 -14.3190
7 O5x O 27.0095 -12.2190
8 O5x O 29.4440 -16.3742
9 C1b C 27.0637 -15.0147
10 C1b C 25.8261 -14.3132
11 C1b C 24.6389 -15.0088
12 C1b C 23.4014 -14.3074
13 N1y N 22.2159 -15.0496
14 C1x C 20.9783 -14.3482
15 C1x C 22.2197 -16.4482
16 C1x C 19.7911 -15.0437
17 C1x C 20.9859 -17.1454
18 N1y N 19.7949 -16.4424
19 C8y C 18.5612 -17.1396
20 N5x N 17.3702 -16.4366
21 N5x N 18.5183 -18.5383
22 C8x C 16.0664 -17.1338
23 C8x C 17.3311 -19.2338
24 C8x C 16.0935 -18.5308
25 C1x C 32.0020 -13.3124
26 C1x C 32.8245 -12.1795
27 C1x C 32.0012 -11.0471
28 C1x C 30.6698 -11.4802
29 X Cl 32.5491 -16.1055
BOND 31
1 1 2 1
2 1 3 1
3 2 4 1
4 3 5 1
5 4 6 1
6 4 7 2
7 5 8 2
8 6 9 1
9 9 10 1
10 10 11 1
11 11 12 1
12 12 13 1
13 13 14 1
14 13 15 1
15 14 16 1
16 15 17 1
17 16 18 1
18 18 19 1
19 19 20 1
20 19 21 2
21 20 22 2
22 21 23 1
23 22 24 1
24 5 6 1
25 17 18 1
26 23 24 2
27 1 25 1
28 25 26 1
29 26 27 1
30 27 28 1
31 1 28 1
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