| Entry |
|
|---|
| Name |
Valproate sodium (USAN);
Sodium valproate (JP18);
Depakene (TN);
Selenica (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C8H15O2. Na
|
|---|
| Exact mass |
166.097
|
|---|
| Mol weight |
166.1933
|
|---|
| Structure |
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|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01575 Calcium channel blocker
DG01573 Calcium channel T type blocker
Neuropsychiatric agent
DG03199 Antiepileptic agent
DG02035 Fatty acid antiepileptic
|
|---|
| Remark |
| Product (DG00849): | D00399<US> D00304<US> D00710<JP/US> |
|
|---|
| Efficacy |
Anticonvulsant, Antimanic, Antimigraine, Antiepileptic |
|---|
| Comment |
Fatty acid derivative
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N03 ANTIEPILEPTICS
N03A ANTIEPILEPTICS
N03AG Fatty acid derivatives
N03AG01 Valproic acid
D00710 Valproate sodium (USAN) <JP/US>
USP drug classification [BR:br08302]
Anticonvulsants
Anticonvulsants, Other
Valproic Acid
D00710 Valproate sodium (USAN)
Antimigraine Agents
Antimigraine Agents, Other
Valproic Acid
D00710 Valproate sodium (USAN)
Bipolar Agents
Mood Stabilizers
Valproic Acid
D00710 Valproate sodium (USAN)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
113 Antiepileptics
1139 Others
D00710 Valproate sodium (USAN); Sodium valproate (JP18)
117 Psychotropics
1179 Others
D00710 Valproate sodium (USAN); Sodium valproate (JP18)
Drug groups [BR:br08330]
Cardiovascular agent
DG01575 Calcium channel blocker
DG01573 Calcium channel T type blocker
DG00849 Valproic acid
D00710 Valproate sodium
Neuropsychiatric agent
DG03199 Antiepileptic agent
DG02035 Fatty acid antiepileptic
DG00849 Valproic acid
D00710 Valproate sodium
Drug classes [BR:br08332]
Neuropsychiatric agent
DG03199 Antiepileptic agent
D00710 Valproate sodium
Target-based classification of drugs [BR:br08310]
Ion channels
Voltage-gated ion channels
Calcium channels
CACNA1-T
D00710 Valproate sodium (USAN) <JP/US>
Enzymes
Oxidoreductases (EC1)
Dehydrogenases
SSADH
D00710 Valproate sodium (USAN) <JP/US>
Transferases (EC2)
Aminotransferase
ABAT
D00710 Valproate sodium (USAN) <JP/US>
Lyases (EC4)
Carboxy-lyases
GAD
D00710 Valproate sodium (USAN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00710 Sodium valproate
D00710 Sodium valproate tablets
D00710 Sodium valproate extended-release tablets A
D00710 Sodium valproate extended-release tablets B
D00710 Sodium valproate syrup
Pharmacogenomic biomarkers [br08341.html]
Polymorphisms and mutations affecting drug response
D00710
Drug groups [BR:br08330]
Cardiovascular agent
DG01575 Calcium channel blocker
DG01573 Calcium channel T type blocker
DG00849 Valproic acid
Neuropsychiatric agent
DG03199 Antiepileptic agent
DG02035 Fatty acid antiepileptic
DG00849 Valproic acid
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 11
1 C1c C 24.8619 -18.6957
2 C1b C 24.8619 -17.3175
3 C1b C 23.6530 -19.4139
4 C6a C 26.0650 -19.4139
5 C1b C 23.6472 -16.6109
6 C1b C 22.4441 -18.6957
7 O6a O 27.2738 -18.6957
8 O6a O 26.0650 -20.8098 #-
9 C1a C 22.4384 -17.3175
10 C1a C 21.2412 -19.4139
11 Z Na 28.5001 -20.7280 #+
BOND 9
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 3 6 1
6 4 7 2
7 4 8 1
8 5 9 1
9 6 10 1
|
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