| Entry |
|
|---|
| Name |
Thiamylal sodium (JP18);
Surital (TN) |
|---|
| Formula |
C12H17N2O2S. Na
|
|---|
| Exact mass |
276.0908
|
|---|
| Mol weight |
276.3303
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
| Therapeutic category: | 1115 |
| Product (DG01377): | D00713<JP> |
|
|---|
| Efficacy |
Anesthetic (intravenous) |
|---|
| Comment |
Barbiturates
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07230 | GABA-A receptor agonists/antagonists |
|
|---|
| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
111 General anesthetics
1115 Barbiturates and thiobarbiturates
D00713 Thiamylal sodium (JP18)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01837 Barbiturate sedative-hypnotics
DG01377 Thiamylal
D00713 Thiamylal sodium
DG01567 GABA-A receptor agonist
DG01377 Thiamylal
D00713 Thiamylal sodium
DG02030 Anesthetics
DG02027 General anesthetics
DG02025 Barbiturate anesthetics
DG01377 Thiamylal
D00713 Thiamylal sodium
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
GABA (ionotropic)
GABR
D00713 Thiamylal sodium (JP18) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00713 Thiamylal sodium
D00713 Thiamylal sodium for injection
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01837 Barbiturate sedative-hypnotics
DG01377 Thiamylal
DG01567 GABA-A receptor agonist
DG01377 Thiamylal
DG02030 Anesthetics
DG02027 General anesthetics
DG02025 Barbiturate anesthetics
DG01377 Thiamylal
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 18
1 C1z C 26.1276 -18.6319
2 C5x C 26.1276 -20.0395
3 C5x C 24.9186 -17.9370
4 C1c C 27.5235 -18.6319
5 C1b C 26.1218 -17.2361
6 N1x N 24.9186 -20.7461
7 O5x O 27.3308 -20.7461
8 N2x N 23.6980 -18.6319
9 O5x O 24.9012 -16.5295
10 C1b C 28.2127 -17.4172
11 C1a C 28.4987 -19.6306
12 C2b C 27.3308 -16.5353
13 C2y C 23.6980 -20.0395
14 C1b C 29.6084 -17.4172
15 C2a C 27.3308 -15.1395
16 S1a S 22.4775 -20.7344 #-
17 C1a C 30.3034 -16.2082
18 Z Na 20.0940 -20.8783 #+
BOND 17
1 1 2 1
2 1 3 1
3 1 4 1
4 1 5 1
5 2 6 1
6 2 7 2
7 3 8 1
8 3 9 2
9 4 10 1
10 4 11 1
11 5 12 1
12 6 13 1
13 10 14 1
14 12 15 2
15 13 16 1
16 14 17 1
17 8 13 2
|
|---|
