| Entry |
|
|---|
| Name |
Methscopolamine bromide (USP);
Hyoscine methobromide (INN);
Pamine (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C18H24NO4. Br
|
|---|
| Exact mass |
397.0889
|
|---|
| Mol weight |
398.2915
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antispasmodic, Muscarinic acetylcholine receptor antagonist |
|---|
| Disease |
|
|---|
| Comment |
Toropane derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07220 | Cholinergic and anticholinergic drugs |
|
|---|
| Brite |
USP drug classification [BR:br08302]
Gastrointestinal Agents
Antispasmodics, Gastrointestinal
Methscopolamine
D00715 Methscopolamine bromide (USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
D00715 Methscopolamine bromide
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D00715 Methscopolamine bromide (USP) <US>
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 24
1 X Br 39.7175 -18.0800 #-
2 C1y C 27.7900 -17.2900
3 C1y C 27.1600 -18.3400
4 C1y C 28.7000 -16.9400
5 O2x O 26.2500 -17.2900
6 C1y C 28.4900 -17.8500
7 N2y N 27.7200 -15.8900 #+
8 C1x C 30.1700 -16.9400
9 C1x C 30.1000 -17.8500
10 C1a C 28.0700 -14.6300
11 C1a C 26.4600 -15.1900
12 C1y C 31.4300 -18.4100
13 O7a O 32.4100 -19.1800
14 C7a C 33.8100 -19.1800
15 O6a O 34.4400 -20.3700
16 C1c C 34.4400 -18.0600
17 C8y C 35.7700 -18.0600
18 C1b C 33.8100 -16.8700
19 O1a O 34.4400 -15.6800
20 C8x C 36.4700 -19.2500
21 C8x C 37.8000 -19.2500
22 C8x C 38.5000 -18.0600
23 C8x C 37.8000 -16.8700
24 C8x C 36.4700 -16.8700
BOND 26
1 2 3 1
2 2 4 1
3 2 5 1
4 3 6 1
5 4 7 1
6 4 8 1
7 6 9 1
8 7 10 1
9 7 11 1
10 8 12 1
11 12 13 1 #Down
12 3 5 1
13 6 7 1
14 9 12 1
15 13 14 1
16 14 15 2
17 14 16 1
18 16 17 1 #Down
19 16 18 1
20 18 19 1
21 17 20 2
22 20 21 1
23 21 22 2
24 22 23 1
25 23 24 2
26 17 24 1
|
|---|
