| Entry |
|
|---|
| Name |
Mepenzolate bromide (JP18/INN);
Cantil (TN) |
|---|
| Formula |
C21H26NO3. Br
|
|---|
| Exact mass |
419.1096
|
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| Mol weight |
420.34
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
|
|---|
| Remark |
| Therapeutic category: | 1231 |
| Product (DG00040): | D00720<JP> |
|
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| Efficacy |
Antispasmodic, Anti-ulcerative, Muscarinic acetylcholine receptor antagonist |
|---|
| Comment |
Quaternary ammonium compound
|
|---|
| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
|
|---|
| Structure map |
| map07220 | Cholinergic and anticholinergic drugs |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
A03A DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
A03AB Synthetic anticholinergics, quaternary ammonium compounds
A03AB12 Mepenzolate
D00720 Mepenzolate bromide (JP18/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
12 Agents affecting peripheral nervous system
123 Autonomic nervous system agents
1231 Quaternary ammoniums
D00720 Mepenzolate bromide (JP18/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00040 Mepenzolate
D00720 Mepenzolate bromide
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D00720 Mepenzolate bromide (JP18/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00720 Mepenzolate bromide
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00040 Mepenzolate
|
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| Other DBs |
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| KCF data |
ATOM 26
1 X Br 20.3708 -17.3488 #-
2 C1x C 22.4560 -15.3909
3 C1x C 23.6669 -14.6918
4 C1y C 24.8779 -15.3909
5 O7a O 26.0887 -14.6918
6 C7a C 27.2996 -15.3909
7 C1d C 28.5106 -14.6918
8 C8y C 29.7214 -15.3909
9 C8x C 30.9323 -14.6918
10 C8x C 29.7214 -16.7891
11 C8x C 30.9323 -17.4882
12 C8x C 32.1433 -16.7891
13 C8x C 32.1433 -15.3909
14 C8y C 28.5106 -13.2938
15 C8x C 29.7422 -12.5824
16 C8x C 29.7420 -11.1842
17 C8x C 28.5309 -10.4853
18 C8x C 27.2993 -11.1967
19 C8x C 27.2995 -12.5949
20 O6a O 27.2996 -16.7890
21 C1x C 24.8779 -16.7889
22 C1x C 22.4560 -16.7891
23 N2y N 23.6669 -17.4882 #+
24 C1a C 24.3660 -18.6991
25 C1a C 22.9678 -18.6991
26 O1a O 29.7214 -13.9927
BOND 27
1 2 3 1
2 3 4 1
3 4 5 1
4 5 6 1
5 6 7 1
6 7 8 1
7 8 9 1
8 8 10 2
9 10 11 1
10 11 12 2
11 12 13 1
12 9 13 2
13 7 14 1
14 14 15 2
15 15 16 1
16 16 17 2
17 17 18 1
18 18 19 2
19 14 19 1
20 6 20 2
21 4 21 1
22 2 22 1
23 22 23 1
24 23 21 1
25 23 24 1
26 23 25 1
27 7 26 1
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