 | | DRUG: Mycophenolate mofetil | |
| Entry |
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| Name |
Mycophenolate mofetil (JAN/USP);
Cellcept (TN) |
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| Product |
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| Generic |
MYCOPHENOLATE MOFETIL (A-S Medication Solutions), MYCOPHENOLATE MOFETIL (ARMAS PHARMACEUTICALS), MYCOPHENOLATE MOFETIL (Accord Healthcare), MYCOPHENOLATE MOFETIL (Advagen Pharma Limited), MYCOPHENOLATE MOFETIL (Akorn), MYCOPHENOLATE MOFETIL (Akorn), MYCOPHENOLATE MOFETIL (American Health Packaging), MYCOPHENOLATE MOFETIL (American Health Packaging), MYCOPHENOLATE MOFETIL (Amneal Pharmaceuticals LLC), MYCOPHENOLATE MOFETIL (Amneal Pharmaceuticals NY LLC), MYCOPHENOLATE MOFETIL (Amneal Pharmaceuticals NY LLC), MYCOPHENOLATE MOFETIL (Amneal Pharmaceuticals NY LLC), MYCOPHENOLATE MOFETIL (Aphena Pharma Solutions - Tennessee), MYCOPHENOLATE MOFETIL (Ascend Laboratories), MYCOPHENOLATE MOFETIL (Ascend Laboratories), MYCOPHENOLATE MOFETIL (Aurobindo Pharma Limited), MYCOPHENOLATE MOFETIL (Aurobindo Pharma Limited), MYCOPHENOLATE MOFETIL (AvPAK), MYCOPHENOLATE MOFETIL (Bryant Ranch Prepack), MYCOPHENOLATE MOFETIL (CONCORD BIOTECH LIMITED), MYCOPHENOLATE MOFETIL (Cardinal Health 107), MYCOPHENOLATE MOFETIL (Cardinal Health 107), MYCOPHENOLATE MOFETIL (Golden State Medical Supply), MYCOPHENOLATE MOFETIL (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), MYCOPHENOLATE MOFETIL (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), MYCOPHENOLATE MOFETIL (Hikma Pharmaceuticals USA), MYCOPHENOLATE MOFETIL (Lannett Company), MYCOPHENOLATE MOFETIL (Lupin Pharmaceuticals), MYCOPHENOLATE MOFETIL (Major Pharmaceuticals), MYCOPHENOLATE MOFETIL (Major Pharmaceuticals), MYCOPHENOLATE MOFETIL (Meitheal Pharmaceuticals), MYCOPHENOLATE MOFETIL (Meitheal Pharmaceuticals), MYCOPHENOLATE MOFETIL (Mylan Institutional LLC), MYCOPHENOLATE MOFETIL (Mylan Institutional), MYCOPHENOLATE MOFETIL (Mylan Pharmaceuticals), MYCOPHENOLATE MOFETIL (NorthStar RxLLC), MYCOPHENOLATE MOFETIL (Par Pharmaceutical), MYCOPHENOLATE MOFETIL (Proficient Rx LP), MYCOPHENOLATE MOFETIL (REMEDYREPACK), MYCOPHENOLATE MOFETIL (REMEDYREPACK), MYCOPHENOLATE MOFETIL (REMEDYREPACK), MYCOPHENOLATE MOFETIL (REMEDYREPACK), MYCOPHENOLATE MOFETIL (STELIS BIOPHARMA LIMITED), MYCOPHENOLATE MOFETIL (Sandoz), MYCOPHENOLATE MOFETIL (Steriscience Pte. Limited), MYCOPHENOLATE MOFETIL (Strides Pharma Science Limited), MYCOPHENOLATE MOFETIL (Teva Pharmaceuticals USA), MYCOPHENOLATE MOFETIL (Teva Pharmaceuticals USA), MYCOPHENOLATE MOFETIL (Teva Pharmaceuticals), MYCOPHENOLATE MOFETIL (VistaPharm), MYCOPHENOLATE MOFETIL (Zydus Lifesciences Limited), MYCOPHENOLATE MOFETIL (Zydus Pharmaceuticals USA), MYCOPHENOLATE MOFETIL (airis PHARMA Private Limited) |
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| Formula |
C23H31NO7
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| Exact mass |
433.2101
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| Mol weight |
433.4947
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| Structure |
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| Simcomp |
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| Remark |
| Therapeutic category: | 3999 |
| Product (DG00739): | D00752<JP/US> D05094<US> D05095<US> |
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| Efficacy |
Immunosuppressant, Inosine monophosphate dehydrogenase inhibitor |
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| Disease |
Prophylaxis of organ rejection [DS: H00083] |
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| Comment |
Active form of prodrug: Mycophenolic acid [DR: D05096]
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| Target |
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| Pathway |
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| Interaction |
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L04 IMMUNOSUPPRESSANTS
L04A IMMUNOSUPPRESSANTS
L04AA Selective immunosuppressants
L04AA06 Mycophenolic acid
D00752 Mycophenolate mofetil (JAN/USP) <JP/US>
USP drug classification [BR:br08302]
Immunological Agents
Immunosuppressants
Antimetabolites, Antiproliferative
Mycophenolic Acid
D00752 Mycophenolate mofetil (JAN/USP)
Therapeutic category of drugs in Japan [BR:br08301]
3 Agents affecting metabolism
39 Other agents affecting metabolism
399 Miscellaneous
3999 Others
D00752 Mycophenolate mofetil (JAN/USP)
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Dehydrogenases
IMPDH
D00752 Mycophenolate mofetil (JAN/USP) <JP/US>
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
D00752
Pharmacogenomic biomarkers [br08341.html]
Polymorphisms and mutations affecting drug response
D00752
Prodrugs [br08324.html]
D00752
Prodrugs [br08324.html]
DG00739
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| Other DBs |
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| KCF data |
ATOM 31
1 C8y C 32.4696 -17.7102
2 C8y C 32.4638 -16.2982
3 C8y C 31.2561 -18.4045
4 C1x C 33.8058 -18.1420
5 C8y C 31.2561 -15.5981
6 C7x C 33.7999 -15.8664
7 C8y C 30.0424 -17.7102
8 C1a C 31.2561 -19.8107
9 O7x O 34.6284 -17.0042
10 C8y C 30.0424 -16.2982
11 O1a O 31.2561 -14.1978
12 O6a O 34.2376 -14.5304
13 O2a O 28.8289 -18.4045
14 C1b C 28.8289 -15.5981
15 C1a C 28.8289 -19.8107
16 C2b C 27.6154 -16.2925
17 C2c C 26.4017 -15.5923
18 C1b C 25.1939 -16.2866
19 C1a C 26.4076 -14.1920
20 C1b C 23.9804 -15.5864
21 C7a C 22.7668 -16.2749
22 O7a O 21.5532 -15.5807
23 O6a O 22.7610 -17.6810
24 C1b C 20.3455 -16.2691
25 C1b C 19.1377 -15.5747
26 N1y N 17.9242 -16.2632
27 C1x C 16.7164 -15.5631
28 C1x C 17.9183 -17.6578
29 C1x C 15.5087 -16.2575
30 C1x C 16.7048 -18.3579
31 O2x O 15.5728 -17.6519
BOND 33
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 3 8 1
8 4 9 1
9 5 10 2
10 5 11 1
11 6 12 2
12 7 13 1
13 10 14 1
14 13 15 1
15 14 16 1
16 16 17 2
17 17 18 1
18 17 19 1
19 18 20 1
20 20 21 1
21 21 22 1
22 21 23 2
23 22 24 1
24 24 25 1
25 25 26 1
26 26 27 1
27 26 28 1
28 27 29 1
29 28 30 1
30 29 31 1
31 6 9 1
32 7 10 1
33 30 31 1
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