| Entry |
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| Name |
Pipecuronium bromide (JAN/USAN/INN);
Arduan (TN) |
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| Formula |
C35H62N4O4. 2Br
|
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| Exact mass |
760.3138
|
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| Mol weight |
762.6992
|
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| Structure |
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| Simcomp |
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| Class |
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01696 Peripherally-acting muscle relaxant
DG03117 Nondepolarizing neuromuscular blocking agent
DG01742 Quaternary ammonium compound type muscle relaxant
|
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| Remark |
|
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| Efficacy |
Neuromuscular blocking agent |
|---|
| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Interaction |
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| Structure map |
| map07221 | Nicotinic cholinergic receptor antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M03 MUSCLE RELAXANTS
M03A MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS
M03AC Other quaternary ammonium compounds
M03AC06 Pipecuronium bromide
D00764 Pipecuronium bromide (JAN/USAN/INN)
Drug groups [BR:br08330]
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01696 Peripherally-acting muscle relaxant
DG03117 Nondepolarizing neuromuscular blocking agent
D00764 Pipecuronium bromide
DG01742 Quaternary ammonium compound type muscle relaxant
D00764 Pipecuronium bromide
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Acetylcholine (nicotinic)
CHRN (neuronal type)
D00764 Pipecuronium bromide (JAN/USAN/INN)
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| Other DBs |
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| KCF data |
ATOM 45
1 C1y C 26.3513 -19.6618
2 C1y C 25.1118 -20.3392
3 C1z C 26.2988 -18.3126
4 C1x C 28.6265 -19.6906
5 C1y C 23.9479 -19.6444
6 C1x C 25.1118 -21.6941
7 C1y C 27.4799 -17.6525
8 C1x C 25.1347 -17.6236
9 C1a C 26.3277 -17.0214
10 C1y C 28.6438 -18.3416
11 C1z C 22.6971 -20.3219
12 C1x C 23.9594 -18.2953
13 C1x C 23.9363 -22.3658
14 O7a O 27.5610 -16.0022
15 N1y N 29.8251 -17.6757
16 C1y C 22.6909 -21.6885
17 C1x C 21.5912 -19.6386
18 C1a C 22.6150 -19.0133
19 C7a C 26.3913 -15.3016
20 C1x C 30.9889 -18.3705
21 C1x C 29.8365 -16.3266
22 C1x C 21.5912 -22.3600
23 C1y C 20.4216 -20.3219
24 C1a C 25.2101 -15.9733
25 O6a O 26.4087 -13.9467
26 C1x C 32.1759 -17.7104
27 C1x C 31.0178 -15.6549
28 C1y C 20.4216 -21.6885
29 N1y N 19.1013 -19.4359
30 N2y N 32.1932 -16.3555 #+
31 O7a O 19.2403 -22.3600
32 C1x C 19.1072 -18.0867
33 C1x C 17.9258 -20.1249
34 C7a C 19.2403 -23.7151
35 C1x C 17.9258 -17.4093
36 C1x C 16.7504 -19.4417
37 C1a C 18.0592 -24.3983
38 O6a O 20.4216 -24.3983
39 N2y N 16.7563 -18.0867 #+
40 C1a C 15.5458 -17.3855
41 C1a C 15.5523 -18.7818
42 C1a C 33.6164 -15.6757
43 C1a C 33.6058 -17.0506
44 X Br 16.6600 -15.6100 #-
45 X Br 32.2700 -19.4600 #-
BOND 48
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 3 8 1
8 3 9 1 #Up
9 4 10 1
10 5 11 1
11 5 12 1
12 6 13 1
13 7 14 1 #Up
14 10 15 1 #Up
15 11 16 1
16 11 17 1
17 11 18 1 #Up
18 14 19 1
19 15 20 1
20 15 21 1
21 16 22 1
22 17 23 1
23 19 24 1
24 19 25 2
25 20 26 1
26 21 27 1
27 22 28 1
28 23 29 1 #Up
29 26 30 1
30 28 31 1 #Down
31 29 32 1
32 29 33 1
33 31 34 1
34 32 35 1
35 33 36 1
36 34 37 1
37 34 38 2
38 35 39 1
39 7 10 1
40 8 12 1
41 13 16 1
42 23 28 1
43 27 30 1
44 36 39 1
45 39 40 1
46 39 41 1
47 30 42 1
48 30 43 1
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