| Entry |
|
|---|
| Name |
Biperiden (JAN/USP/INN);
Akineton (TN) |
|---|
| Formula |
C21H29NO
|
|---|
| Exact mass |
311.2249
|
|---|
| Mol weight |
311.4611
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG01967 Antiparkinson agent
|
|---|
| Remark |
| Product (DG00852): | D02246<JP> D02247<JP> |
|
|---|
| Efficacy |
Antiparkinsonian, Muscarinic acetylcholine receptor antagonist |
|---|
| Comment |
Centrally active anticholinergic drugs
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07220 | Cholinergic and anticholinergic drugs |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N04 ANTI-PARKINSON DRUGS
N04A ANTICHOLINERGIC AGENTS
N04AA Tertiary amines
N04AA02 Biperiden
D00779 Biperiden (JAN/USP/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG00852 Biperiden
D00779 Biperiden
DG01967 Antiparkinson agent
DG00852 Biperiden
D00779 Biperiden
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D00779 Biperiden (JAN/USP/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG00852 Biperiden
DG01967 Antiparkinson agent
DG00852 Biperiden
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 23
1 C1y C 26.3034 -7.3312
2 C1d C 26.3034 -8.7346
3 C1y C 27.5665 -6.6295
4 C1x C 25.1105 -6.6295
5 C8y C 27.5665 -9.4363
6 C1b C 25.1105 -9.4363
7 C1x C 26.5841 -5.6471
8 C2x C 27.5665 -5.2260
9 C1y C 25.1105 -5.2260
10 C8x C 27.5665 -10.8397
11 C8x C 28.7594 -8.7346
12 C1b C 23.9176 -8.7346
13 C2x C 26.3736 -4.5243
14 C8x C 28.6892 -11.5414
15 C8x C 29.9523 -9.5065
16 N1y N 22.6545 -9.4363
17 C8x C 29.9523 -10.8397
18 C1x C 22.6545 -10.8397
19 C1x C 21.4616 -8.7346
20 C1x C 21.4616 -11.4713
21 C1x C 20.2687 -9.4363
22 C1x C 20.2687 -10.7696
23 O1a O 27.5188 -8.0329
BOND 26
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 3 8 1
8 4 9 1
9 5 10 1
10 5 11 2
11 6 12 1
12 8 13 2
13 10 14 2
14 11 15 1
15 12 16 1
16 14 17 1
17 16 18 1
18 16 19 1
19 18 20 1
20 19 21 1
21 20 22 1
22 7 9 1
23 9 13 1
24 15 17 2
25 21 22 1
26 2 23 1
|
|---|
