| Entry |
|
|---|
| Name |
Chlorprothixene (JAN/USAN/INN);
Taractan (TN) |
|---|
| Formula |
C18H18ClNS
|
|---|
| Exact mass |
315.0848
|
|---|
| Mol weight |
315.8602
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antipsychotic, Dopamine receptor antagonist |
|---|
| Comment |
Thioxanthene derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AF Thioxanthene derivatives
N05AF03 Chlorprothixene
D00790 Chlorprothixene (JAN/USAN/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG00894 Chlorprothixene
D00790 Chlorprothixene
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD1
D00790 Chlorprothixene (JAN/USAN/INN)
DRD2
D00790 Chlorprothixene (JAN/USAN/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG00894 Chlorprothixene
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 21
1 C8x C 22.8268 -17.0417
2 C8x C 22.8268 -18.4443
3 C8x C 24.0414 -19.1456
4 C8y C 25.2562 -18.4443
5 C8y C 25.2562 -17.0417
6 C8x C 24.0414 -16.3404
7 S2x S 26.4709 -19.1456
8 C8y C 27.6856 -18.4443
9 C8y C 27.6856 -17.0417
10 C8y C 26.4709 -16.3404
11 C8x C 28.9005 -19.1456
12 C8x C 30.1151 -18.4443
13 C8y C 30.1151 -17.0417
14 C8x C 28.9005 -16.3404
15 C2b C 26.4709 -14.9377
16 C1b C 27.6877 -14.2352
17 C1b C 28.8865 -14.9275
18 N1c N 30.0756 -14.2410
19 C1a C 31.2693 -14.9305
20 C1a C 30.0758 -12.8340
21 X Cl 31.3339 -16.3381
BOND 23
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 8 11 2
13 11 12 1
14 12 13 2
15 13 14 1
16 9 14 2
17 10 15 2
18 15 16 1
19 16 17 1
20 17 18 1
21 18 19 1
22 18 20 1
23 13 21 1
|
|---|
