Entry |
|
Name |
Metrifonate (USP/INN); Trichlorfon (USAN) |
Formula |
C4H8Cl3O4P
|
Exact mass |
255.9226
|
Mol weight |
257.4367
|
Structure |
|
Simcomp |
|
Class |
Neuropsychiatric agent
DG01595 Cholinesterase inhibitor
DG01593 Acetylcholinesterase inhibitor
|
Remark |
|
Efficacy |
Anthelmintic (veterinary), Acetylcholinesterase inhibitor |
Comment |
Organophosphorous compound
|
Target |
acetylcholinesterase (AChE) [KO: K01049] butyrylcholinesterase (BChE) [KO: K01050] |
Pathway |
|
Interaction |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
P ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
P02 ANTHELMINTICS
P02B ANTITREMATODALS
P02BB Organophosphorous compounds
P02BB01 Metrifonate
D00805 Metrifonate (USP/INN)
Classification of Japanese OTC drugs [BR:br08313]
Agents for sanitation
82 Pesticides
D00805 Metrifonate (USP/INN)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Not used for human
Insecticides
D00805 Metrifonate (USP/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01595 Cholinesterase inhibitor
DG01593 Acetylcholinesterase inhibitor
D00805 Metrifonate
Antimicrobials [BR:br08307]
Antiparasitics
Antitrematodal agents
Organophosphorous compounds
D00805 Metrifonate (USP/INN)
|
Other DBs |
|
KCF data |
ATOM 12
1 C1c C 23.6267 -16.3786
2 P1b P 22.2173 -16.3786
3 C1d C 24.3225 -17.5892
4 O1a O 24.3225 -15.1681
5 O2b O 20.8138 -16.3786
6 O2b O 22.2173 -17.7880
7 O3b O 22.2173 -14.9751
8 X Cl 23.6267 -18.7998
9 X Cl 25.7203 -17.5892
10 X Cl 25.3109 -18.5774
11 C1a C 20.1237 -15.1681
12 C1a C 21.0068 -18.4838
BOND 11
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 2 7 2
7 3 8 1
8 3 9 1
9 3 10 1
10 5 11 1
11 6 12 1
|