| Entry |
|
|---|
| Name |
Butorphanol tartrate (JAN/USP);
Stadol (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C21H29NO2. C4H6O6
|
|---|
| Exact mass |
477.2363
|
|---|
| Mol weight |
477.5473
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01564 Opioid receptor agonist
Analgesic
DG01984 Opioid analgesics
|
|---|
| Remark |
| Product (DG00821): | D00837<US> |
|
|---|
| Efficacy |
Analgesic, Antitussive, Opioid receptor agonist/antagonist |
|---|
| Comment |
Opioid alkaloid, morphinan
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07224 | Opioid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N02 ANALGESICS
N02A OPIOIDS
N02AF Morphinan derivatives
N02AF01 Butorphanol
D00837 Butorphanol tartrate (JAN/USP) <US>
USP drug classification [BR:br08302]
Analgesics
Opioid Analgesics, Short-acting
Butorphanol
D00837 Butorphanol tartrate (JAN/USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG00821 Butorphanol
D00837 Butorphanol tartrate
Analgesic
DG01984 Opioid analgesics
DG00821 Butorphanol
D00837 Butorphanol tartrate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D00837 Butorphanol tartrate (JAN/USP) <US>
OPRK1
D00837 Butorphanol tartrate (JAN/USP) <US>
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG00821 Butorphanol
Analgesic
DG01984 Opioid analgesics
DG00821 Butorphanol
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 34
1 C1z C 14.4241 -15.0906
2 C1z C 15.5897 -15.7724
3 C8y C 14.4241 -13.7327
4 C1x C 15.7120 -14.2164
5 C1x C 13.2411 -15.7549
6 C1y C 16.7784 -15.0381
7 C1x C 15.5897 -17.1243
8 O1a O 16.7667 -16.4600
9 C8y C 15.5954 -13.0567
10 C8x C 13.2354 -13.0567
11 C1x C 17.9613 -14.2107
12 C1x C 13.2294 -17.1127
13 N1y N 17.9613 -15.6966
14 C1x C 16.7726 -13.7444
15 C1x C 14.4067 -17.7887
16 C8x C 15.5954 -11.6990
17 C8y C 13.2354 -11.6990
18 C1b C 19.3133 -15.6966
19 C8x C 14.4298 -11.0171
20 O1a O 12.0639 -11.0171
21 C1y C 19.9952 -16.8737
22 C1x C 19.6456 -18.1849
23 C1x C 21.3180 -17.2176
24 C1x C 20.9626 -18.5289
25 C1c C 23.4100 -14.8283
26 C1c C 24.6163 -14.1290
27 C6a C 22.1979 -14.1407
28 O1a O 23.4042 -16.2270
29 C6a C 25.8226 -14.8226
30 O1a O 24.6046 -12.7304
31 O6a O 20.9859 -14.8343
32 O6a O 22.1922 -12.7363
33 O6a O 27.0348 -14.1233
34 O6a O 25.8168 -16.2210
BOND 37
1 1 2 1
2 1 3 1
3 1 4 1 #Up
4 1 5 1
5 2 6 1
6 2 7 1
7 2 8 1 #Up
8 3 9 2
9 3 10 1
10 4 11 1
11 5 12 1
12 6 13 1 #Up
13 6 14 1
14 7 15 1
15 9 16 1
16 10 17 2
17 13 18 1
18 16 19 2
19 17 20 1
20 18 21 1
21 21 22 1
22 21 23 1
23 22 24 1
24 9 14 1
25 13 11 1 #Up
26 12 15 1
27 17 19 1
28 23 24 1
29 25 26 1
30 25 27 1
31 25 28 1 #Up
32 26 29 1
33 26 30 1 #Up
34 27 31 1
35 27 32 2
36 29 33 1
37 29 34 2
|
|---|
