| Entry |
|
|---|
| Name |
Paromomycin sulfate (JAN/USP);
Humatin (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C23H45N5O14. xH2SO4
|
|---|
| Structure |
|
|---|
| Simcomp |
|
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| Class |
Antibacterial
DG01447 Aminoglycoside antibiotic
|
|---|
| Remark |
| Therapeutic category: | 6419 |
| Product (DG00084): | D00868<JP/US> |
|
|---|
| Efficacy |
Antibiotic, Amebicide, Protein biosynthesis inhibitor |
|---|
| Disease |
Intestinal amebiasis [DS: H00360] |
|---|
| Target |
30S ribosomal subunit |
|---|
| Pathway |
|
|---|
| Interaction |
|
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
A07A INTESTINAL ANTIINFECTIVES
A07AA Antibiotics
A07AA06 Paromomycin
D00868 Paromomycin sulfate (JAN/USP) <JP/US>
USP drug classification [BR:br08302]
Antibacterials
Aminoglycosides
Paromomycin
D00868 Paromomycin sulfate (JAN/USP)
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
64 Parasitics (systemic)
641 Antiprotozoans
6419 Others
D00868 Paromomycin sulfate (JAN/USP)
Drug groups [BR:br08330]
Antibacterial
DG01447 Aminoglycoside antibiotic
DG00084 Paromomycin
D00868 Paromomycin sulfate
Drug classes [BR:br08332]
Antibacterial
DG01447 Aminoglycoside antibiotic
D00868 Paromomycin sulfate
Antimicrobials [BR:br08307]
Antibacterials
Protein biosynthesis inhibitor
Aminoglycoside
D00868 Paromomycin sulfate (JAN/USP) <JP/US>
New drug approvals in Japan [br08318.html]
Drugs with new active ingredients
D00868
Drug groups [BR:br08330]
Antibacterial
DG01447 Aminoglycoside antibiotic
DG00084 Paromomycin
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Protein biosynthesis inhibitor
Aminoglycoside
DG00084 Paromomycin
|
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| Other DBs |
|
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| KCF data |
ATOM 47
1 C1y C 15.3963 -21.6422
2 C1y C 15.3963 -23.0324
3 C1y C 16.5971 -23.7310
4 C1y C 17.7980 -23.0324
5 C1y C 17.7980 -21.6422
6 O2x O 16.5971 -20.9505
7 O2a O 19.0033 -20.9514
8 C1y C 21.2124 -19.8245
9 C1y C 21.6430 -18.5027
10 O2x O 20.5140 -17.6796
11 C1y C 19.3848 -18.5027
12 C1y C 19.8223 -19.8245
13 O2a O 23.1747 -18.0701
14 O1a O 23.5419 -20.8494
15 C1y C 24.7414 -20.1499
16 C1y C 25.9503 -20.8328
17 C1x C 27.1498 -20.1333
18 C1y C 27.1403 -18.7438
19 C1y C 25.9312 -18.0538
20 C1y C 24.7318 -18.7604
21 N1a N 25.9599 -22.2229
22 N1a N 28.3334 -18.0369
23 O2a O 25.9217 -16.6637
24 C1y C 27.1218 -15.9636
25 O2x O 28.3163 -16.6488
26 C1y C 29.5865 -15.9489
27 C1y C 29.5763 -14.5586
28 C1y C 28.2972 -13.8683
29 C1y C 27.1041 -14.5752
30 C1b C 30.7260 -16.6322
31 O1a O 30.7357 -18.0224
32 N1a N 25.8923 -13.8885
33 O1a O 28.2875 -12.4781
34 O1a O 30.7070 -13.8516
35 C1b C 18.0617 -18.0701
36 O1a O 22.0243 -20.9515
37 O1a O 17.0349 -19.0040
38 C1b C 14.1917 -20.9498
39 O1a O 14.1917 -23.7317
40 N1a N 19.0033 -23.7302
41 O1a O 16.5988 -25.1213
42 N1a N 12.9863 -21.6410
43 O1d O 32.8616 -22.2234
44 S4a S 32.8546 -23.6067
45 O1d O 34.2379 -23.6067
46 O1d O 31.4714 -23.6067
47 O1d O 32.8476 -24.9900
BOND 49
1 19 23 1 #Down
2 20 13 1 #Up
3 10 11 1
4 24 23 1 #Down
5 11 12 1
6 12 8 1
7 5 6 1
8 9 13 1 #Up
9 6 1 1
10 24 25 1
11 25 26 1
12 26 27 1
13 27 28 1
14 28 29 1
15 29 24 1
16 26 30 1 #Up
17 15 14 1 #Down
18 30 31 1
19 5 7 1 #Down
20 29 32 1 #Down
21 28 33 1 #Up
22 1 2 1
23 27 34 1 #Down
24 2 3 1
25 11 35 1 #Up
26 12 7 1 #Down
27 3 4 1
28 8 36 1 #Down
29 15 16 1
30 35 37 1
31 16 17 1
32 1 38 1 #Down
33 17 18 1
34 2 39 1 #Down
35 18 19 1
36 4 40 1 #Down
37 19 20 1
38 3 41 1 #Up
39 20 15 1
40 38 42 1
41 4 5 1
42 16 21 1 #Up
43 8 9 1
44 18 22 1 #Up
45 9 10 1
46 43 44 2
47 44 45 1
48 44 46 1
49 44 47 2
BRACKET 1 30.1000 -25.9000 30.1000 -21.2800
1 35.4900 -21.2800 35.4900 -25.9000
1 x
ORIGINAL 1 43 44 45 46 47
REPEAT 1
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