| Entry |
|
|---|
| Name |
Spectinomycin hydrochloride (USP);
Spectinomycin hydrochloride hydrate (JP18);
Trobicin (TN) |
|---|
| Formula |
C14H24N2O7. 2HCl. 5H2O
|
|---|
| Exact mass |
494.1645
|
|---|
| Mol weight |
495.3478
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antibacterial
DG01447 Aminoglycoside antibiotic
|
|---|
| Remark |
| Therapeutic category: | 6129 |
| Product (DG00634): | D00869<JP> |
|
|---|
| Efficacy |
Antibacterial, Protein biosynthesis inhibitor |
|---|
| Target |
30S ribosomal subunit |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01X OTHER ANTIBACTERIALS
J01XX Other antibacterials
J01XX04 Spectinomycin
D00869 Spectinomycin hydrochloride (USP) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
61 Antibiotics
612 Acting mainly on gram-negative bacteria
6129 Others
D00869 Spectinomycin hydrochloride (USP); Spectinomycin hydrochloride hydrate (JP18)
Drug groups [BR:br08330]
Antibacterial
DG01447 Aminoglycoside antibiotic
DG00634 Spectinomycin
D00869 Spectinomycin hydrochloride
Drug classes [BR:br08332]
Antibacterial
DG01447 Aminoglycoside antibiotic
D00869 Spectinomycin hydrochloride
Antimicrobials [BR:br08307]
Antibacterials
Protein biosynthesis inhibitor
Aminoglycoside
D00869 Spectinomycin hydrochloride (USP) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00869 Spectinomycin hydrochloride hydrate
D00869 Spectinomycin hydrochloride for injection
Drug groups [BR:br08330]
Antibacterial
DG01447 Aminoglycoside antibiotic
DG00634 Spectinomycin
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Protein biosynthesis inhibitor
Aminoglycoside
DG00634 Spectinomycin
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 30
1 C1y C 8.8211 -14.0729
2 C1y C 8.8211 -12.6739
3 C1y C 7.6065 -14.7787
4 O2x O 10.0421 -14.7724
5 O2x O 10.0358 -11.9616
6 C1y C 7.6065 -11.9807
7 C1y C 6.4109 -14.0729
8 N1b N 7.6065 -16.1651
9 C1z C 11.3394 -14.1491
10 C1y C 11.3267 -12.6675
11 C1y C 6.4109 -12.6739
12 O1a O 7.6065 -10.7406
13 O1a O 5.2091 -14.7597
14 C1a C 6.4047 -16.8519
15 C5x C 12.5732 -14.7787
16 O1a O 11.3331 -15.7328
17 O2x O 12.6177 -11.9363
18 N1b N 5.2156 -11.9807
19 C1x C 13.8069 -14.1364
20 O5x O 12.5859 -16.0951
21 C1y C 13.7877 -12.6357
22 C1a C 4.0135 -12.6739
23 C1a C 14.9770 -11.9363
24 X Cl 19.3200 -12.1800
25 O0 O 19.8100 -15.1900
26 X Cl 19.3200 -12.1800
27 O0 O 19.8100 -15.1900
28 O0 O 19.8100 -15.1900
29 O0 O 19.8100 -15.1900
30 O0 O 19.8100 -15.1900
BOND 25
1 1 2 1
2 1 3 1
3 1 4 1 #Down
4 2 5 1 #Up
5 2 6 1
6 3 7 1
7 3 8 1 #Up
8 4 9 1
9 5 10 1
10 6 11 1
11 6 12 1 #Down
12 7 13 1 #Up
13 8 14 1
14 9 15 1
15 9 16 1 #Up
16 10 17 1
17 11 18 1 #Up
18 15 19 1
19 15 20 2
20 17 21 1
21 18 22 1
22 21 23 1 #Down
23 7 11 1
24 9 10 1
25 19 21 1
BRACKET 1 17.5700 -13.1600 17.5700 -11.2700
1 20.5100 -11.2700 20.5100 -13.1600
1 2
ORIGINAL 1 25
REPEAT 1 27
2 17.3600 -15.9600 17.3600 -14.3500
2 20.8600 -14.3500 20.8600 -15.9600
2 5
ORIGINAL 2 26
REPEAT 2 28 29 30 31
|
|---|
