| Entry |
|
|---|
| Name |
Naftifine hydrochloride (USP);
Naftin (TN) |
|---|
| Product |
|
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| Generic |
|
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| Formula |
C21H21N. HCl
|
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| Exact mass |
323.1441
|
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| Mol weight |
323.8591
|
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| Structure |
|
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| Simcomp |
|
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| Remark |
| Product (DG00377): | D00883<US> |
|
|---|
| Efficacy |
Antifungal, Ergosterol biosynthesis inhibitor |
|---|
| Comment |
Allylamine derivative
|
|---|
| Target |
squalene epoxidase [KO: K00511] |
|---|
| Pathway |
|
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D01 ANTIFUNGALS FOR DERMATOLOGICAL USE
D01A ANTIFUNGALS FOR TOPICAL USE
D01AE Other antifungals for topical use
D01AE22 Naftifine
D00883 Naftifine hydrochloride (USP) <US>
USP drug classification [BR:br08302]
Dermatological Agents
Topical Anti-infectives
Antifungals, dermatological
Naftifine
D00883 Naftifine hydrochloride (USP)
Antimicrobials [BR:br08307]
Antifungals
Ergosterol biosynthesis inhibitor
Other ergosterol biosynthesis inhibitor
D00883 Naftifine hydrochloride (USP) <US>
|
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| Other DBs |
|
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| KCF data |
ATOM 23
1 C8x C 23.6600 -25.4100
2 C8x C 23.6600 -26.8100
3 C8x C 24.8724 -27.5100
4 C8y C 26.0849 -26.8100
5 C8y C 26.0849 -25.4100
6 C8x C 24.8724 -24.7100
7 C8x C 27.2973 -27.5100
8 C8x C 28.5097 -26.8100
9 C8x C 28.5097 -25.4100
10 C8y C 27.2973 -24.7100
11 C1b C 27.2973 -23.3100
12 N1c N 28.5118 -22.6088
13 C1b C 29.7083 -23.2998
14 C1a C 28.5118 -21.2102
15 C2b C 30.8951 -22.6146
16 C2b C 32.0866 -23.3028
17 C8y C 33.2760 -22.6161
18 C8x C 34.4662 -23.3035
19 C8x C 35.6787 -22.6037
20 C8x C 35.6789 -21.2037
21 C8x C 34.4887 -20.5163
22 C8x C 33.2762 -21.2161
23 X Cl 34.5800 -26.5300
BOND 24
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 2
9 8 9 1
10 9 10 2
11 5 10 1
12 10 11 1
13 11 12 1
14 12 13 1
15 12 14 1
16 13 15 1
17 15 16 2
18 16 17 1
19 17 18 2
20 18 19 1
21 19 20 2
22 20 21 1
23 21 22 2
24 17 22 1
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