| Entry |
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| Name |
Natamycin (USP/INN);
Pimaricin (JP18);
Natacyn (TN) |
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| Product |
|
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| Formula |
C33H47NO13
|
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| Exact mass |
665.3047
|
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| Mol weight |
665.7252
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| Structure |
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| Simcomp |
|
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| Sequence |
0 Mak 1 Mad 2 Mad 3 Mad 4 Mad 5 Mak 6 Mak 7 Mtk 8 Man
9 Mak 10 Mad 11 Mad 12 Man |
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| Type |
PK |
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| Source |
Streptomyces natalensis [TAX: 68242]
|
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| Remark |
| Therapeutic category: | 1317 |
|
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| Efficacy |
Antibacterial, Antifungal |
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| Comment |
Polyene
|
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| Target |
Ergosterol |
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A01 STOMATOLOGICAL PREPARATIONS
A01A STOMATOLOGICAL PREPARATIONS
A01AB Antiinfectives and antiseptics for local oral treatment
A01AB10 Natamycin
D00884 Natamycin (USP/INN) <JP/US>
A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
A07A INTESTINAL ANTIINFECTIVES
A07AA Antibiotics
A07AA03 Natamycin
D00884 Natamycin (USP/INN) <JP/US>
D DERMATOLOGICALS
D01 ANTIFUNGALS FOR DERMATOLOGICAL USE
D01A ANTIFUNGALS FOR TOPICAL USE
D01AA Antibiotics
D01AA02 Natamycin
D00884 Natamycin (USP/INN) <JP/US>
G GENITO URINARY SYSTEM AND SEX HORMONES
G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
G01AA Antibiotics
G01AA02 Natamycin
D00884 Natamycin (USP/INN) <JP/US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AA Antibiotics
S01AA10 Natamycin
D00884 Natamycin (USP/INN) <JP/US>
USP drug classification [BR:br08302]
Ophthalmic Agents
Ophthalmic Anti-Infectives
Antifungal, Ophthalmic
Natamycin
D00884 Natamycin (USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
13 Agents affecting sensory organs
131 Ophthalmic agents
1317 Ophthalmic antibiotics
D00884 Natamycin (USP/INN); Pimaricin (JP18)
Antimicrobials [BR:br08307]
Antifungals
Cell membrane function inhibitor
Polyene macrolide
D00884 Natamycin (USP/INN) <JP/US>
Antimicrobials abbreviations [BR:br08327]
Antifungals
Cell membrane function inhibitor
Polyene macrolide
D00884 Natamycin (USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00884 Pimaricin
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| Other DBs |
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| KCF data |
ATOM 47
1 C1y C 13.7782 -18.2793
2 O2x O 12.5596 -17.5821
3 C1y C 11.3432 -18.2826
4 C1y C 11.3451 -19.6873
5 C1y C 12.5634 -20.3916
6 C1y C 13.7800 -19.6841
7 C1y C 12.5738 -11.9903
8 C1y C 12.5738 -13.3918
9 C1y C 13.7913 -14.0890
10 O2x O 14.9948 -13.3918
11 C1z C 14.9948 -11.9903
12 C1x C 13.7913 -11.2859
13 C1b C 16.2008 -11.2859
14 C1c C 17.4122 -11.9832
15 C1b C 18.6233 -11.2790
16 C1y C 19.8348 -11.9763
17 C1y C 21.0462 -11.2719
18 C2b C 22.2574 -11.9692
19 C2b C 23.4617 -11.2648
20 O6a O 25.8845 -11.2579
21 C1b C 13.7932 -15.4905
22 C1c C 15.0018 -16.1932
23 C2b C 16.2078 -15.4834
24 C2b C 17.4191 -16.1876
25 C2b C 18.6304 -15.4834
26 C2b C 19.8419 -16.1876
27 C2b C 21.0531 -15.4834
28 C2b C 22.2645 -16.1876
29 C2b C 23.4688 -15.4834
30 C2b C 24.6801 -16.1876
31 C1b C 25.8913 -15.4834
32 C1c C 25.8845 -14.0819
33 O7a O 24.6663 -13.3908
34 C7a C 24.6590 -11.9832
35 O2x O 19.8277 -10.5748
36 O1a O 17.4051 -13.3847
37 O1a O 14.9824 -10.5888
38 O2a O 14.9894 -17.5892
39 C1a C 27.0957 -13.3776
40 O1a O 11.3554 -11.2859
41 C6a C 11.3554 -14.0819
42 O1a O 10.1230 -20.3780
43 N1a N 12.5652 -21.7930
44 O1a O 14.9886 -20.3867
45 C1a C 10.1276 -17.5870
46 O6a O 10.1448 -13.3778
47 O6a O 11.3475 -15.4834
BOND 50
1 12 7 1
2 24 25 1
3 6 1 1
4 25 26 2
5 11 13 1
6 26 27 1
7 27 28 2
8 13 14 1
9 28 29 1
10 1 2 1
11 29 30 2
12 14 15 1
13 30 31 1
14 2 3 1
15 31 32 1
16 15 16 1
17 32 33 1
18 3 4 1
19 33 34 1
20 16 17 1
21 16 35 1
22 17 35 1
23 4 5 1
24 14 36 1 #Down
25 17 18 1
26 11 37 1 #Down
27 5 6 1
28 18 19 2
29 22 38 1 #Down
30 19 34 1
31 32 39 1 #Down
32 7 8 1
33 7 40 1 #Up
34 34 20 2
35 8 41 1 #Down
36 1 38 1 #Down
37 8 9 1
38 4 42 1 #Down
39 9 21 1
40 5 43 1 #Up
41 9 10 1
42 6 44 1 #Up
43 21 22 1
44 3 45 1 #Up
45 10 11 1
46 41 46 2
47 22 23 1
48 41 47 1
49 11 12 1
50 23 24 2
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