| Entry |
|
|---|
| Name |
Sulconazole nitrate (JAN/USP);
Exelderm (TN) |
|---|
| Product |
|
|---|
| Formula |
C18H15Cl3N2S. HNO3
|
|---|
| Exact mass |
458.9978
|
|---|
| Mol weight |
460.7619
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antifungal
DG01883 Imidazole antifungal
|
|---|
| Remark |
| Therapeutic category: | 2655 |
| Product (DG00366): | D00886<JP/US> |
|
|---|
| Efficacy |
Antifungal, Ergosterol biosynthesis inhibitor |
|---|
| Disease |
|
|---|
| Comment |
Imidazole derivative
|
|---|
| Target |
sterol 14alpha-demethylase [KO: K05917] |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D01 ANTIFUNGALS FOR DERMATOLOGICAL USE
D01A ANTIFUNGALS FOR TOPICAL USE
D01AC Imidazole and triazole derivatives
D01AC09 Sulconazole
D00886 Sulconazole nitrate (JAN/USP) <JP/US>
USP drug classification [BR:br08302]
Dermatological Agents
Topical Anti-infectives
Antifungals, dermatological
Sulconazole
D00886 Sulconazole nitrate (JAN/USP)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
26 Epidermides
265 Antiparasitic dermatosis agents
2655 Imidazoles
D00886 Sulconazole nitrate (JAN/USP)
Classification of Japanese OTC drugs [BR:br08313]
Agents for integumentary system
58 Ringworm drugs
D00886 Sulconazole nitrate (JAN/USP)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Sulconazole
D00886 Sulconazole nitrate (JAN/USP)
Drug groups [BR:br08330]
Antifungal
DG01883 Imidazole antifungal
DG00366 Sulconazole
D00886 Sulconazole nitrate
Drug classes [BR:br08332]
Antifungal
DG01883 Imidazole antifungal
D00886 Sulconazole nitrate
Antimicrobials [BR:br08307]
Antifungals
Ergosterol biosynthesis inhibitor
Imidazole
D00886 Sulconazole nitrate (JAN/USP) <JP/US>
Rx-to-OTC switch list in Japan [br08314.html]
D00886
Drug groups [BR:br08330]
Antifungal
DG01883 Imidazole antifungal
DG00366 Sulconazole
|
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| Other DBs |
|
|---|
| KCF data |
ATOM 28
1 N2b N 39.2735 -20.6975 #+
2 O3a O 39.2676 -19.3000
3 O3a O 40.4959 -21.3962 #-
4 O1b O 38.0517 -21.4097
5 C8y C 26.0400 -14.4900
6 C8x C 26.0400 -15.8900
7 C8x C 27.2524 -16.5900
8 C8y C 28.4649 -15.8900
9 C8x C 28.4649 -14.4900
10 C8x C 27.2524 -13.7900
11 X Cl 24.8276 -13.7900
12 C1b C 29.6960 -16.6010
13 S2a S 30.9012 -15.9053
14 C1c C 32.0835 -16.5881
15 C1b C 33.2775 -15.8988
16 C8y C 32.0835 -17.9898
17 N4y N 34.4654 -16.5848
18 C8x C 34.8840 -17.9125
19 C8y C 30.8535 -18.7001
20 C8x C 30.8536 -20.1001
21 C8y C 32.0661 -20.8000
22 C8x C 33.2961 -20.0897
23 C8x C 33.2960 -18.6897
24 N5x N 36.2839 -17.9244
25 C8x C 36.7278 -16.5966
26 C8x C 35.6023 -15.7642
27 X Cl 29.6491 -18.0048
28 X Cl 32.0662 -22.1900
BOND 29
1 1 2 2
2 1 3 1
3 1 4 1
4 5 6 2
5 6 7 1
6 7 8 2
7 8 9 1
8 9 10 2
9 5 10 1
10 5 11 1
11 8 12 1
12 12 13 1
13 13 14 1
14 14 15 1
15 14 16 1
16 15 17 1
17 17 18 1
18 16 19 2
19 19 20 1
20 20 21 2
21 21 22 1
22 22 23 2
23 16 23 1
24 18 24 2
25 24 25 1
26 25 26 2
27 17 26 1
28 19 27 1
29 21 28 1
|
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