| Entry |
|
|---|
| Name |
Cefpodoxime proxetil (JP18/USP);
Vantin (TN) |
|---|
| Product |
|
|---|
| Generic |
CEFPODOXIME PROXETIL (Amici Pharmaceuticals), CEFPODOXIME PROXETIL (Amici Pharmaceuticals), CEFPODOXIME PROXETIL (Ascend Laboratories), CEFPODOXIME PROXETIL (Ascend Laboratories), CEFPODOXIME PROXETIL (Aurobindo Pharma Limited), CEFPODOXIME PROXETIL (Aurobindo Pharma Limited), CEFPODOXIME PROXETIL (Cronus Pharma LLC), CEFPODOXIME PROXETIL (Golden State Medical Supply), CEFPODOXIME PROXETIL (NorthStar Rx LLC), CEFPODOXIME PROXETIL (NorthStar Rx LLC), CEFPODOXIME PROXETIL (NuCare Pharmaceuticals), CEFPODOXIME PROXETIL (NuCare Pharmaceuticals), CEFPODOXIME PROXETIL (PD-Rx Pharmaceuticals), CEFPODOXIME PROXETIL (Rising Pharma Holdings), CEFPODOXIME PROXETIL (Sandoz) |
|---|
| Formula |
C21H27N5O9S2
|
|---|
| Exact mass |
557.125
|
|---|
| Mol weight |
557.5972
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
| Therapeutic category: | 6132 |
| Product (DG00582): | D00920<JP/US> |
|
|---|
| Efficacy |
Antibacterial, Cell wall biosynthesis inhibitor |
|---|
| Comment |
Active form of prodrug: Cefpodoxime [DR: D07650]
|
|---|
| Target |
penicillin binding protein |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01D OTHER BETA-LACTAM ANTIBACTERIALS
J01DD Third-generation cephalosporins
J01DD13 Cefpodoxime
D00920 Cefpodoxime proxetil (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
Antibacterials
Beta-lactam, Cephalosporins
Cefpodoxime
D00920 Cefpodoxime proxetil (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
61 Antibiotics
613 Acting mainly on gram-positive and gram-negative bacteria
6132 Cephem antibioitics
D00920 Cefpodoxime proxetil (JP18/USP)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00582 Cefpodoxime
D00920 Cefpodoxime proxetil
DG01776 Third-generation cephalosporin
DG00582 Cefpodoxime
D00920 Cefpodoxime proxetil
DG01804 Oxyimino beta-lactam
DG00582 Cefpodoxime
D00920 Cefpodoxime proxetil
Drug classes [BR:br08332]
Antibacterial
DG01488 Cephem
D00920 Cefpodoxime proxetil
Antimicrobials [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Third-generation cephalosporin
D00920 Cefpodoxime proxetil (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00920 Cefpodoxime proxetil
D00920 Cefpodoxime proxetil tablets
D00920 Cefpodoxime proxetil for syrup
Prodrugs [br08324.html]
D00920
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00582 Cefpodoxime
DG01776 Third-generation cephalosporin
DG00582 Cefpodoxime
DG01804 Oxyimino beta-lactam
DG00582 Cefpodoxime
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Third-generation cephalosporin
DG00582 Cefpodoxime
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 37
1 C1y C 31.5842 -17.3805
2 N1y N 31.5842 -18.7567
3 C2y C 32.7540 -19.4449
4 C2y C 33.9239 -18.7567
5 C1x C 33.9239 -17.3805
6 S2x S 32.7540 -16.6923
7 C1y C 30.2079 -17.3805
8 C5x C 30.2079 -18.7567
9 N1b N 28.9691 -16.6923
10 C5a C 27.7993 -17.3805
11 O5a O 27.7993 -18.7567
12 O5x O 28.9691 -19.4449
13 C2c C 26.6294 -16.6923
14 C1b C 35.1627 -19.4449
15 C8y C 25.3906 -17.3805
16 C8x C 24.3584 -16.5546
17 S2x S 23.1886 -17.3116
18 C8y C 23.6015 -18.6879
19 N5x N 24.9777 -18.6879
20 N2b N 26.6294 -15.3158
21 C7a C 32.7540 -21.7845
22 O7a O 33.9239 -22.4727
23 O6a O 31.5154 -22.4727
24 N1a N 22.7757 -19.7889
25 O2a O 36.3407 -18.7387
26 C1a C 37.5407 -19.4054
27 C1c C 35.1193 -21.7954
28 O7a O 36.2775 -22.4768
29 C1a C 35.0621 -20.4067
30 C7a C 37.4637 -21.8047
31 O7a O 38.6645 -22.5115
32 C1c C 39.8522 -21.8393
33 O6a O 37.4747 -20.4063
34 C1a C 41.0316 -22.5338
35 C1a C 39.8639 -20.4752
36 O2a O 27.8164 -14.6368
37 C1a C 27.8164 -13.2368
BOND 39
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 1
7 1 7 1
8 7 8 1
9 2 8 1
10 7 9 1 #Up
11 9 10 1
12 10 11 2
13 8 12 2
14 10 13 1
15 4 14 1
16 13 15 1
17 15 16 2
18 16 17 1
19 17 18 1
20 18 19 2
21 15 19 1
22 13 20 2
23 3 21 1
24 21 22 1
25 21 23 2
26 18 24 1
27 14 25 1
28 25 26 1
29 22 27 1
30 27 28 1
31 27 29 1
32 28 30 1
33 30 31 1
34 31 32 1
35 30 33 2
36 32 34 1
37 32 35 1
38 20 36 1
39 36 37 1
|
|---|
