 | | DRUG: Ceftriaxone sodium | |
| Entry |
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| Name |
Ceftriaxone sodium (USP);
Ceftriaxone sodium hydrate (JP18);
Rocephin (TN) |
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| Product |
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| Generic |
CEFTRIAXONE (Baxter Healthcare Corporation), CEFTRIAXONE (Civica), CEFTRIAXONE (Fresenius Kabi USA), CEFTRIAXONE (Hikma Pharmaceuticals USA), CEFTRIAXONE (Hikma Pharmaceuticals USA), CEFTRIAXONE (Proficient Rx LP), CEFTRIAXONE (Sagent Pharmaceuticals), CEFTRIAXONE (Sagent Pharmaceuticals), CEFTRIAXONE (Samson Medical Technologies), CEFTRIAXONE (WG Critical Care), CEFTRIAXONE (WG Critical Care), CEFTRIAXONE (WG Critical Care), CEFTRIAXONE (Xellia Pharmaceuticals USA LLC), CEFTRIAXONE (Xellia Pharmaceuticals USA LLC), CEFTRIAXONE SODIUM (A-S Medication Solutions), CEFTRIAXONE SODIUM (A-S Medication Solutions), CEFTRIAXONE SODIUM (A-S Medication Solutions), CEFTRIAXONE SODIUM (A-S Medication Solutions), CEFTRIAXONE SODIUM (Apotex Corp.), CEFTRIAXONE SODIUM (Apotex Corp.), CEFTRIAXONE SODIUM (Asclemed USA), CEFTRIAXONE SODIUM (Hospira), CEFTRIAXONE SODIUM (Hospira), CEFTRIAXONE SODIUM (Hospira), CEFTRIAXONE SODIUM (Hospira), CEFTRIAXONE SODIUM (Hospira), CEFTRIAXONE SODIUM (Hospira), CEFTRIAXONE SODIUM (Proficient Rx LP), CEFTRIAXONE SODIUM (Proficient Rx LP), CEFTRIAXONE SODIUM (Proficient Rx LP), CEFTRIAXONE SODIUM (Qilu Pharmaceutical), CEFTRIAXONE SODIUM (REMEDYREPACK), CEFTRIAXONE SODIUM (REMEDYREPACK), CEFTRIAXONE SODIUM (REMEDYREPACK), CEFTRIAXONE SODIUM (Sandoz), CEFTRIAXONE SODIUM (Sandoz) |
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| Formula |
(C18H16N8O7S3. 2Na)2. 7H2O
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| Exact mass |
1322.0938
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| Mol weight |
1323.1941
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| Structure |
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| Simcomp |
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| Class |
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| Remark |
| Therapeutic category: | 6132 |
| Product (DG00573): | D00924<JP/US> |
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| Efficacy |
Antibacterial, Cell wall biosynthesis inhibitor |
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| Disease |
Uncomplicated urinary tract infections [DS: H01176] |
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| Target |
penicillin binding protein |
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| Pathway |
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| Interaction |
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| Structure map |
| map07012 | Cephalosporins - parenteral agents |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01D OTHER BETA-LACTAM ANTIBACTERIALS
J01DD Third-generation cephalosporins
J01DD04 Ceftriaxone
D00924 Ceftriaxone sodium (USP) <JP/US>
USP drug classification [BR:br08302]
Antibacterials
Beta-lactam, Cephalosporins
Ceftriaxone
D00924 Ceftriaxone sodium (USP)
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
61 Antibiotics
613 Acting mainly on gram-positive and gram-negative bacteria
6132 Cephem antibioitics
D00924 Ceftriaxone sodium (USP); Ceftriaxone sodium hydrate (JP18)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00573 Ceftriaxone
D00924 Ceftriaxone sodium
DG01776 Third-generation cephalosporin
DG00573 Ceftriaxone
D00924 Ceftriaxone sodium
DG01804 Oxyimino beta-lactam
DG00573 Ceftriaxone
D00924 Ceftriaxone sodium
Drug classes [BR:br08332]
Antibacterial
DG01488 Cephem
D00924 Ceftriaxone sodium
Antimicrobials [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Third-generation cephalosporin
D00924 Ceftriaxone sodium (USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00924 Ceftriaxone sodium hydrate
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00573 Ceftriaxone
DG01776 Third-generation cephalosporin
DG00573 Ceftriaxone
DG01804 Oxyimino beta-lactam
DG00573 Ceftriaxone
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Third-generation cephalosporin
DG00573 Ceftriaxone
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| Other DBs |
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| KCF data |
ATOM 83
1 C1y C 23.0416 -18.7698
2 N1y N 23.0416 -20.1004
3 C2y C 24.3021 -20.8007
4 C2y C 25.4927 -20.1004
5 C1x C 25.4927 -18.7698
6 S2x S 24.3021 -18.0694
7 C1y C 21.6409 -18.7698
8 C5x C 21.6409 -20.1004
9 N1b N 20.4503 -18.0694
10 C5a C 19.2598 -18.7698
11 O5a O 19.2598 -20.1004
12 O5x O 20.4503 -20.8007
13 C2c C 18.0692 -18.0694
14 C1b C 26.6833 -20.8707
15 C8y C 16.8086 -18.7698
16 C8x C 15.6881 -17.9294
17 S2x S 14.5675 -18.7698
18 C8y C 14.9878 -20.1703
19 N5x N 16.3885 -20.1703
20 N2b N 18.0692 -16.5988
21 C6a C 24.3021 -22.2014
22 O6a O 25.4927 -22.9717 #-
23 O6a O 23.0416 -22.9017
24 S2a S 27.8738 -20.1703
25 C8y C 29.0644 -20.8707
26 N1a N 14.1474 -21.2909
27 N5x N 29.0644 -22.2714
28 C8y C 30.2550 -22.9717
29 C8y C 31.5156 -22.2714
30 N4x N 31.5156 -20.8707 #-
31 N4y N 30.2550 -20.1703
32 O5x O 30.2550 -24.3724
33 O5x O 32.7062 -22.9717
34 C1a C 30.2550 -18.7698
35 O2a O 19.2771 -15.8881
36 C1a C 19.2656 -14.4979
37 Z Na 26.9634 -22.9017 #+
38 Z Na 32.8461 -20.8707 #+
39 O0 O 36.9782 -20.6606
40 C1y C 23.0416 -18.7698
41 N1y N 23.0416 -20.1004
42 C2y C 24.3021 -20.8007
43 C2y C 25.4927 -20.1004
44 C1x C 25.4927 -18.7698
45 S2x S 24.3021 -18.0694
46 C1b C 26.6833 -20.8707
47 S2a S 27.8738 -20.1703
48 C8y C 29.0644 -20.8707
49 N5x N 29.0644 -22.2714
50 C8y C 30.2550 -22.9717
51 C8y C 31.5156 -22.2714
52 N4x N 31.5156 -20.8707 #-
53 N4y N 30.2550 -20.1703
54 C1a C 30.2550 -18.7698
55 O5x O 32.7062 -22.9717
56 O5x O 30.2550 -24.3724
57 C6a C 24.3021 -22.2014
58 O6a O 25.4927 -22.9717 #-
59 O6a O 23.0416 -22.9017
60 C5x C 21.6409 -20.1004
61 C1y C 21.6409 -18.7698
62 N1b N 20.4503 -18.0694
63 C5a C 19.2598 -18.7698
64 O5a O 19.2598 -20.1004
65 C2c C 18.0692 -18.0694
66 C8y C 16.8086 -18.7698
67 C8x C 15.6881 -17.9294
68 S2x S 14.5675 -18.7698
69 C8y C 14.9878 -20.1703
70 N5x N 16.3885 -20.1703
71 N1a N 14.1474 -21.2909
72 N2b N 18.0692 -16.5988
73 O2a O 19.2771 -15.8881
74 C1a C 19.2656 -14.4979
75 O5x O 20.4503 -20.8007
76 Z Na 26.9634 -22.9017 #+
77 Z Na 32.8461 -20.8707 #+
78 O0 O 36.9782 -20.6606
79 O0 O 36.9782 -20.6606
80 O0 O 36.9782 -20.6606
81 O0 O 36.9782 -20.6606
82 O0 O 36.9782 -20.6606
83 O0 O 36.9782 -20.6606
BOND 78
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 1
7 1 7 1
8 7 8 1
9 2 8 1
10 7 9 1 #Up
11 9 10 1
12 10 11 2
13 8 12 2
14 10 13 1
15 4 14 1
16 13 15 1
17 15 16 2
18 16 17 1
19 17 18 1
20 18 19 2
21 15 19 1
22 13 20 2
23 3 21 1
24 21 22 1
25 21 23 2
26 14 24 1
27 24 25 1
28 18 26 1
29 25 27 2
30 27 28 1
31 28 29 1
32 29 30 1
33 30 31 1
34 25 31 1
35 28 32 2
36 29 33 2
37 31 34 1
38 20 35 1
39 35 36 1
40 40 41 1
41 41 42 1
42 42 43 2
43 43 44 1
44 44 45 1
45 40 45 1
46 40 61 1
47 61 60 1
48 41 60 1
49 61 62 1 #Up
50 62 63 1
51 63 64 2
52 60 75 2
53 63 65 1
54 43 46 1
55 65 66 1
56 66 67 2
57 67 68 1
58 68 69 1
59 69 70 2
60 66 70 1
61 65 72 2
62 42 57 1
63 57 58 1
64 57 59 2
65 46 47 1
66 47 48 1
67 69 71 1
68 48 49 2
69 49 50 1
70 50 51 1
71 51 52 1
72 52 53 1
73 48 53 1
74 50 56 2
75 51 55 2
76 53 54 1
77 72 73 1
78 73 74 1
BRACKET 1 12.5300 -24.6400 12.5300 -15.2600
1 33.9500 -15.2600 33.9500 -24.6400
1 2
ORIGINAL 1 1 2 3 4 5 6 14 25 26 28 29 30 31 32 35 34
1 33 22 23 24 8 7 9 10 11 13 15 17 18 19 20 27
1 21 36 37 12 16 38 39
REPEAT 1 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56
1 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72
1 73 74 75 76 77 78 79
2 35.0000 -21.2100 35.0000 -19.8100
2 37.3800 -19.8100 37.3800 -21.2100
2 7
ORIGINAL 2 40
REPEAT 2 80 81 82 83 84 85
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