| Entry |
|
|---|
| Name |
Levonorgestrel (JAN/USP/INN);
Mirena (TN);
Norplant (TN);
Skyla (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C21H28O2
|
|---|
| Exact mass |
312.2089
|
|---|
| Mol weight |
312.4458
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Hormonal agent
DG02004 Progesterone
DG01666 Progesterone receptor agonist
|
|---|
| Remark |
| Product (mixture): | D04482<JP/US> D09187<JP/US> |
|
|---|
| Efficacy |
Contraceptive, Progesterone receptor agonist |
|---|
| Comment |
Progestin
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04914 | Progesterone-mediated oocyte maturation |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
G03A HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE
G03AC Progestogens
G03AC03 Levonorgestrel
D00950 Levonorgestrel (JAN/USP/INN) <JP/US>
G03AD Emergency contraceptives
G03AD01 Levonorgestrel
D00950 Levonorgestrel (JAN/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Contraceptives
Oral Progestins
Levonorgestrel
D00950 Levonorgestrel (JAN/USP/INN)
Contraceptives, Other
Levonorgestrel
D00950 Levonorgestrel (JAN/USP/INN)
Hormonal Agents, Stimulant/Replacement/Modifying (Sex Hormones/Modifiers)
Progestins
Levonorgestrel
D00950 Levonorgestrel (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
25 Urogenital and anal organ agents
252 Genital organ agents
2529 Others
D00950 Levonorgestrel (JAN/USP/INN)
254 Contraceptives
2549 Others
D00950 Levonorgestrel (JAN/USP/INN)
Drug groups [BR:br08330]
Hormonal agent
DG02004 Progesterone
D00950 Levonorgestrel
DG01666 Progesterone receptor agonist
D00950 Levonorgestrel
Drug classes [BR:br08332]
Endocrine and hormonal agent
DG02004 Progesterone
D00950 Levonorgestrel
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C3 (PGR)
D00950 Levonorgestrel (JAN/USP/INN) <JP/US>
Rx-to-OTC switch list in the USA [br08315.html]
D00950
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 23
1 C1x C 5.3900 -17.3600
2 C5x C 5.3900 -18.7600
3 C2x C 6.6024 -19.4600
4 C2y C 7.8149 -18.7600
5 C1y C 7.8149 -17.3600
6 C1x C 6.6024 -16.6600
7 C1x C 9.0273 -19.4600
8 C1x C 10.2397 -18.7600
9 C1y C 10.2397 -17.3600
10 C1y C 9.0273 -16.6600
11 C1y C 11.4522 -16.6600
12 C1z C 11.4522 -15.2600
13 C1x C 10.2397 -14.5600
14 C1x C 9.0273 -15.2600
15 C1x C 13.8770 -16.6600
16 C1x C 13.8770 -15.2600
17 C1z C 12.6646 -14.5600
18 O5x O 4.1776 -19.4600
19 C1b C 11.4522 -13.8600
20 O1a O 12.6646 -13.1600
21 C3b C 13.8770 -13.8600
22 C3a C 15.0895 -13.1600
23 C1a C 10.2608 -13.1719
BOND 26
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 9 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 10 14 1
17 11 15 1
18 15 16 1
19 16 17 1
20 12 17 1
21 2 18 2
22 12 19 1 #Up
23 17 20 1 #Up
24 17 21 1 #Down
25 21 22 3
26 19 23 1
|
|---|
