 | | DRUG: Medroxyprogesterone acetate | |
| Entry |
|
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| Name |
Medroxyprogesterone acetate (JP18/USP);
Depo-provera (TN);
Depo-subq provera 104 (TN);
Provera (TN) |
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| Product |
|
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| Generic |
MEDROXYPROGESTERONE (PharmPak), MEDROXYPROGESTERONE ACETATE (A-S Medication Solutions), MEDROXYPROGESTERONE ACETATE (A-S Medication Solutions), MEDROXYPROGESTERONE ACETATE (A-S Medication Solutions), MEDROXYPROGESTERONE ACETATE (A-S Medication Solutions), MEDROXYPROGESTERONE ACETATE (A-S Medication Solutions), MEDROXYPROGESTERONE ACETATE (A-S Medication Solutions), MEDROXYPROGESTERONE ACETATE (A-S Medication Solutions), MEDROXYPROGESTERONE ACETATE (A-S Medication Solutions), MEDROXYPROGESTERONE ACETATE (American Health Packaging), MEDROXYPROGESTERONE ACETATE (Amneal Pharmaceuticals LLC), MEDROXYPROGESTERONE ACETATE (Amphastar Pharmaceuticals), MEDROXYPROGESTERONE ACETATE (Amphastar Pharmaceuticals), MEDROXYPROGESTERONE ACETATE (Bryant Ranch Prepack), MEDROXYPROGESTERONE ACETATE (Bryant Ranch Prepack), MEDROXYPROGESTERONE ACETATE (Bryant Ranch Prepack), MEDROXYPROGESTERONE ACETATE (Bryant Ranch Prepack), MEDROXYPROGESTERONE ACETATE (Bryant Ranch Prepack), MEDROXYPROGESTERONE ACETATE (Cipla USA), MEDROXYPROGESTERONE ACETATE (Eugia US LLC), MEDROXYPROGESTERONE ACETATE (Eugia US LLC), MEDROXYPROGESTERONE ACETATE (Greenstone LLC), MEDROXYPROGESTERONE ACETATE (Greenstone LLC), MEDROXYPROGESTERONE ACETATE (Mylan Institutional LLC), MEDROXYPROGESTERONE ACETATE (Northwind Pharmaceuticals), MEDROXYPROGESTERONE ACETATE (PD-Rx Pharmaceuticals), MEDROXYPROGESTERONE ACETATE (PD-Rx Pharmaceuticals), MEDROXYPROGESTERONE ACETATE (Prasco Laboratories), MEDROXYPROGESTERONE ACETATE (Preferred Pharmaceuticals), MEDROXYPROGESTERONE ACETATE (Preferred Pharmaceuticals), MEDROXYPROGESTERONE ACETATE (Proficient Rx LP), MEDROXYPROGESTERONE ACETATE (Proficient Rx LP), MEDROXYPROGESTERONE ACETATE (REMEDYREPACK), MEDROXYPROGESTERONE ACETATE (REMEDYREPACK), MEDROXYPROGESTERONE ACETATE (REMEDYREPACK), MEDROXYPROGESTERONE ACETATE (REMEDYREPACK), MEDROXYPROGESTERONE ACETATE (RPK Pharmaceuticals), MEDROXYPROGESTERONE ACETATE (Sun Pharmaceutical Industries), MEDROXYPROGESTERONE ACETATE (Sun Pharmaceutical Industries), MEDROXYPROGESTERONE ACETATE (Teva Pharmaceuticals USA), MEDROXYPROGESTERONE ACETATE INJECTABLE SUSPENSION (Hikma Pharmaceuticals USA) |
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| Formula |
C24H34O4
|
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| Exact mass |
386.2457
|
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| Mol weight |
386.5244
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Hormonal agent
DG02004 Progesterone
DG01666 Progesterone receptor agonist
|
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| Remark |
| Therapeutic category: | 2478 |
| Product (DG00458): | D00951<JP/US> |
|
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| Efficacy |
Antineoplastic, Contraceptive, Progesterone receptor agonist |
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| Disease |
|
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| Comment |
Progestin
|
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| Target |
|
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| Pathway |
| hsa04914 | Progesterone-mediated oocyte maturation |
|
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| Network |
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| Interaction |
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| Structure map |
| map07226 | Progesterone, androgen and estrogen receptor agonists/antagonists |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
G03A HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE
G03AC Progestogens
G03AC06 Medroxyprogesterone
D00951 Medroxyprogesterone acetate (JP18/USP) <JP/US>
G03D PROGESTOGENS
G03DA Pregnen (4) derivatives
G03DA02 Medroxyprogesterone
D00951 Medroxyprogesterone acetate (JP18/USP) <JP/US>
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L02 ENDOCRINE THERAPY
L02A HORMONES AND RELATED AGENTS
L02AB Progestogens
L02AB02 Medroxyprogesterone
D00951 Medroxyprogesterone acetate (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
Contraceptives
Contraceptives, Other
Medroxyprogesterone
D00951 Medroxyprogesterone acetate (JP18/USP)
Hormonal Agents, Stimulant/Replacement/Modifying (Sex Hormones/Modifiers)
Progestins
Medroxyprogesterone
D00951 Medroxyprogesterone acetate (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
24 Hormones
247 Estrogen and progesterone preparations
2478 Synthetic progestins
D00951 Medroxyprogesterone acetate (JP18/USP)
Drug groups [BR:br08330]
Hormonal agent
DG02004 Progesterone
DG00458 Medroxyprogesterone
D00951 Medroxyprogesterone acetate
DG01666 Progesterone receptor agonist
DG00458 Medroxyprogesterone
D00951 Medroxyprogesterone acetate
Drug classes [BR:br08332]
Endocrine and hormonal agent
DG02004 Progesterone
D00951 Medroxyprogesterone acetate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C3 (PGR)
D00951 Medroxyprogesterone acetate (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00951 Medroxyprogesterone acetate
Drug groups [BR:br08330]
Hormonal agent
DG02004 Progesterone
DG00458 Medroxyprogesterone
DG01666 Progesterone receptor agonist
DG00458 Medroxyprogesterone
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| Other DBs |
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| KCF data |
ATOM 28
1 C1z C 28.1133 -17.0474
2 C1z C 26.9252 -17.7172
3 C1x C 29.2900 -17.7348
4 O7a O 29.2900 -16.3485
5 C5a C 28.1718 -15.6728
6 C1y C 26.9192 -19.0861
7 C1x C 25.7544 -17.0299
8 C1a C 26.9778 -16.3485
9 C1x C 29.2843 -19.0978
10 C7a C 30.4782 -17.0299
11 C1a C 26.9019 -14.9796
12 O5a O 29.3543 -14.9738
13 C1y C 25.7311 -19.7675
14 C1x C 24.5603 -17.6998
15 C1a C 31.6606 -16.3426
16 O6a O 30.4724 -18.4045
17 C1y C 24.5487 -19.0685
18 C1x C 25.7311 -21.1364
19 C1z C 23.3603 -19.7559
20 C1y C 24.5370 -21.8238
21 C2y C 23.3546 -21.1248
22 C1x C 22.1781 -19.0628
23 C1a C 23.3488 -18.3812
24 C1a C 24.5953 -23.1868
25 C2x C 22.1781 -21.8178
26 C1x C 20.9840 -19.7559
27 C5x C 20.9840 -21.1248
28 O5x O 19.7957 -21.8062
BOND 31
1 1 2 1
2 1 3 1
3 1 4 1 #Down
4 1 5 1 #Up
5 2 6 1
6 2 7 1
7 2 8 1 #Up
8 3 9 1
9 4 10 1
10 5 11 1
11 5 12 2
12 6 13 1
13 7 14 1
14 10 15 1
15 10 16 2
16 13 17 1
17 13 18 1
18 17 19 1
19 18 20 1
20 19 21 1
21 19 22 1
22 19 23 1 #Up
23 20 24 1 #Down
24 21 25 2
25 22 26 1
26 25 27 1
27 27 28 2
28 6 9 1
29 14 17 1
30 20 21 1
31 26 27 1
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