| Entry |
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| Name |
Fenoprofen calcium (JAN/USP);
Nalfon (TN) |
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| Product |
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| Generic |
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| Formula |
(C15H13O3)2. Ca. 2H2O
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| Exact mass |
558.1567
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| Mol weight |
558.6324
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| Structure |
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| Simcomp |
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| Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01908 Anti-inflammatory drug, propionic acid derivatives
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| Remark |
| Product (DG00754): | D00968<US> |
|
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| Efficacy |
Analgesic, Anti-inflammatory, COX inhibitor |
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| Disease |
Rheumatoid arthritis [DS: H00630] |
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| Comment |
Propionic acid derivative
|
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| Target |
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| Pathway |
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| Interaction |
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
M01AE Propionic acid derivatives
M01AE04 Fenoprofen
D00968 Fenoprofen calcium (JAN/USP) <US>
USP drug classification [BR:br08302]
Analgesics
Nonsteroidal Anti-inflammatory Drugs
Fenoprofen
D00968 Fenoprofen calcium (JAN/USP)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01908 Anti-inflammatory drug, propionic acid derivatives
DG00754 Fenoprofen
D00968 Fenoprofen calcium
Drug classes [BR:br08332]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
D00968 Fenoprofen calcium
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D00968 Fenoprofen calcium (JAN/USP) <US>
PTGS2 (COX2)
D00968 Fenoprofen calcium (JAN/USP) <US>
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01908 Anti-inflammatory drug, propionic acid derivatives
DG00754 Fenoprofen
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| Other DBs |
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| KCF data |
ATOM 39
1 Z Ca 36.1429 -23.6003 #2+
2 O0 O 37.1238 -25.7019
3 C8x C 21.9763 -24.2873
4 C8x C 21.9763 -25.6871
5 C8x C 23.1885 -26.3870
6 C8x C 24.4008 -25.6871
7 C8y C 24.4008 -24.2873
8 C8x C 23.1885 -23.5874
9 O2a O 25.6381 -23.5874
10 C8y C 26.8504 -24.2873
11 C8x C 28.0626 -23.5874
12 C8x C 26.8504 -25.6871
13 C8x C 28.0626 -26.3870
14 C8x C 29.2748 -25.6871
15 C8y C 29.2748 -24.2873
16 C1c C 30.4673 -23.5874
17 C6a C 31.6795 -24.2873
18 O6a O 32.8917 -23.5874 #-
19 C1a C 30.4623 -22.1878
20 O6a O 31.6795 -25.6869
21 O0 O 37.1697 -27.4398
22 C8x C 21.9763 -24.2873
23 C8x C 21.9763 -25.6871
24 C8x C 23.1885 -26.3870
25 C8x C 24.4008 -25.6871
26 C8y C 24.4008 -24.2873
27 C8x C 23.1885 -23.5874
28 O2a O 25.6381 -23.5874
29 C8y C 26.8504 -24.2873
30 C8x C 28.0626 -23.5874
31 C8y C 29.2748 -24.2873
32 C8x C 29.2748 -25.6871
33 C8x C 28.0626 -26.3870
34 C8x C 26.8504 -25.6871
35 C1c C 30.4673 -23.5874
36 C6a C 31.6795 -24.2873
37 O6a O 32.8917 -23.5874 #-
38 O6a O 31.6795 -25.6869
39 C1a C 30.4623 -22.1878
BOND 38
1 3 4 2
2 4 5 1
3 5 6 2
4 6 7 1
5 7 8 2
6 3 8 1
7 7 9 1
8 9 10 1
9 10 11 1
10 10 12 2
11 12 13 1
12 13 14 2
13 14 15 1
14 11 15 2
15 15 16 1
16 16 17 1
17 17 18 1
18 16 19 1
19 17 20 2
20 22 23 2
21 23 24 1
22 24 25 2
23 25 26 1
24 26 27 2
25 22 27 1
26 26 28 1
27 28 29 1
28 29 30 1
29 29 34 2
30 34 33 1
31 33 32 2
32 32 31 1
33 30 31 2
34 31 35 1
35 35 36 1
36 36 37 1
37 35 39 1
38 36 38 2
BRACKET 1 21.0000 -28.0700 21.0000 -20.7200
1 33.8800 -20.7200 33.8800 -28.0700
1 2
ORIGINAL 1 3 4 5 6 7 8 9 10 11 15 14 13 12 16 17 18
1 20 19
REPEAT 1 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37
1 38 39
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