| Entry |
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| Name |
Betamethasone sodium phosphate (JP18/USP);
Celestone (TN) |
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| Formula |
C22H28FO8P. 2Na
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| Exact mass |
516.1301
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| Mol weight |
516.4046
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| Structure |
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| Simcomp |
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| Class |
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| Remark |
| Product (DG00095): | D00244<JP> D00972<JP> D01357<JP/US> D01637<JP/US> D02032<JP> |
| Product (mixture): | D04246<JP> D04446<JP/US> |
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| Efficacy |
Anti-inflammatory, Antirheumatic, Glucocorticoid receptor agonist |
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Interaction |
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| Structure map |
| map07225 | Glucocorticoid and mineralocorticoid receptor agonists/antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
A07E INTESTINAL ANTIINFLAMMATORY AGENTS
A07EA Corticosteroids acting locally
A07EA04 Betamethasone
D00972 Betamethasone sodium phosphate (JP18/USP) <JP>
C CARDIOVASCULAR SYSTEM
C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
C05AA Corticosteroids
C05AA05 Betamethasone
D00972 Betamethasone sodium phosphate (JP18/USP) <JP>
D DERMATOLOGICALS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AC Corticosteroids, potent (group III)
D07AC01 Betamethasone
D00972 Betamethasone sodium phosphate (JP18/USP) <JP>
D07X CORTICOSTEROIDS, OTHER COMBINATIONS
D07XC Corticosteroids, potent, other combinations
D07XC01 Betamethasone
D00972 Betamethasone sodium phosphate (JP18/USP) <JP>
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H02 CORTICOSTEROIDS FOR SYSTEMIC USE
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
H02AB Glucocorticoids
H02AB01 Betamethasone
D00972 Betamethasone sodium phosphate (JP18/USP) <JP>
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AD Corticosteroids
R01AD06 Betamethasone
D00972 Betamethasone sodium phosphate (JP18/USP) <JP>
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
R03BA Glucocorticoids
R03BA04 Betamethasone
D00972 Betamethasone sodium phosphate (JP18/USP) <JP>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01B ANTIINFLAMMATORY AGENTS
S01BA Corticosteroids, plain
S01BA06 Betamethasone
D00972 Betamethasone sodium phosphate (JP18/USP) <JP>
S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
S01CB Corticosteroids/antiinfectives/mydriatics in combination
S01CB04 Betamethasone
D00972 Betamethasone sodium phosphate (JP18/USP) <JP>
S02 OTOLOGICALS
S02B CORTICOSTEROIDS
S02BA Corticosteroids
S02BA07 Betamethasone
D00972 Betamethasone sodium phosphate (JP18/USP) <JP>
S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
S03B CORTICOSTEROIDS
S03BA Corticosteroids
S03BA03 Betamethasone
D00972 Betamethasone sodium phosphate (JP18/USP) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
13 Agents affecting sensory organs
131 Ophthalmic agents
1315 Ophthalmic cortisones
D00972 Betamethasone sodium phosphate (JP18/USP)
132 Otic and nasal agents
1329 Others
D00972 Betamethasone sodium phosphate (JP18/USP)
2 Agents affecting individual organs
24 Hormones
245 Adrenal hormone preparations
2454 Fluorinated adrenocorticotropic hormones
D00972 Betamethasone sodium phosphate (JP18/USP)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00095 Betamethasone
D00972 Betamethasone sodium phosphate
Drug classes [BR:br08332]
Anti-inflammatory
DG01955 Corticosteroid
D00972 Betamethasone sodium phosphate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D00972 Betamethasone sodium phosphate (JP18/USP) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00972 Betamethasone sodium phosphate
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00095 Betamethasone
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| Other DBs |
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| KCF data |
ATOM 34
1 C1y C 20.5509 -18.6771
2 C1y C 19.3622 -19.3588
3 C1z C 20.5626 -17.2961
4 C1x C 22.9399 -18.7004
5 C1z C 18.1794 -18.6655
6 C1x C 19.3622 -20.7281
7 C1z C 21.7686 -16.6144
8 C1x C 19.3855 -16.6144
9 C1a C 20.5567 -15.9269
10 C1y C 22.9514 -17.3253
11 C1z C 16.9908 -19.3471
12 C1y C 18.1910 -17.2961
13 X F 18.1677 -20.0289
14 C1x C 18.1677 -21.4098
15 C5a C 21.7745 -15.2451
16 O1a O 23.0913 -16.2589
17 C1a C 24.2741 -17.2381
18 C2y C 16.9849 -20.7222
19 C2x C 15.8021 -18.6596
20 C1a C 16.9791 -17.9662
21 O1a O 17.0025 -16.6028
22 C1b C 22.9573 -14.5575
23 O5a O 20.5743 -14.5575
24 C2x C 15.8021 -21.4040
25 C2x C 14.6135 -19.3471
26 O2b O 24.1401 -15.2334
27 C5x C 14.6135 -20.7222
28 P1b P 25.2763 -14.4585
29 O5x O 13.4190 -21.3981
30 O1c O 26.4534 -15.1461
31 O1c O 26.4068 -13.6836 #-
32 O1c O 24.5014 -13.3223 #-
33 Z Na 28.9880 -14.9538 #+
34 Z Na 28.9181 -18.1935 #+
BOND 35
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 3 8 1
8 3 9 1 #Up
9 4 10 1
10 5 11 1
11 5 12 1
12 5 13 1 #Down
13 6 14 1
14 7 15 1 #Up
15 7 16 1 #Down
16 10 17 1 #Up
17 11 18 1
18 11 19 1
19 11 20 1 #Up
20 12 21 1 #Up
21 15 22 1
22 15 23 2
23 18 24 2
24 19 25 2
25 22 26 1
26 24 27 1
27 26 28 1
28 27 29 2
29 28 30 2
30 28 31 1
31 28 32 1
32 7 10 1
33 8 12 1
34 14 18 1
35 25 27 1
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