| Entry |
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| Name |
Hydrocortisone cypionate |
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| Formula |
C29H42O6
|
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| Exact mass |
486.2981
|
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| Mol weight |
486.6402
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| Structure |
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| Simcomp |
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| Class |
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
|
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| Remark |
|
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| Efficacy |
Anti-inflammatory, Glucocorticoid receptor agonist |
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Metabolism |
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| Interaction |
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| Structure map |
| map07225 | Glucocorticoid and mineralocorticoid receptor agonists/antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A01 STOMATOLOGICAL PREPARATIONS
A01A STOMATOLOGICAL PREPARATIONS
A01AC Corticosteroids for local oral treatment
A01AC03 Hydrocortisone
D00976 Hydrocortisone cypionate
A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
A07E INTESTINAL ANTIINFLAMMATORY AGENTS
A07EA Corticosteroids acting locally
A07EA02 Hydrocortisone
D00976 Hydrocortisone cypionate
C CARDIOVASCULAR SYSTEM
C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
C05AA Corticosteroids
C05AA01 Hydrocortisone
D00976 Hydrocortisone cypionate
D DERMATOLOGICALS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AA Corticosteroids, weak (group I)
D07AA02 Hydrocortisone
D00976 Hydrocortisone cypionate
D07X CORTICOSTEROIDS, OTHER COMBINATIONS
D07XA Corticosteroids, weak, other combinations
D07XA01 Hydrocortisone
D00976 Hydrocortisone cypionate
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H02 CORTICOSTEROIDS FOR SYSTEMIC USE
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
H02AB Glucocorticoids
H02AB09 Hydrocortisone
D00976 Hydrocortisone cypionate
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01B ANTIINFLAMMATORY AGENTS
S01BA Corticosteroids, plain
S01BA02 Hydrocortisone
D00976 Hydrocortisone cypionate
S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
S01CB Corticosteroids/antiinfectives/mydriatics in combination
S01CB03 Hydrocortisone
D00976 Hydrocortisone cypionate
S02 OTOLOGICALS
S02B CORTICOSTEROIDS
S02BA Corticosteroids
S02BA01 Hydrocortisone
D00976 Hydrocortisone cypionate
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00012 Hydrocortisone
D00976 Hydrocortisone cypionate
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG00012 Hydrocortisone
D00976 Hydrocortisone cypionate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D00976 Hydrocortisone cypionate
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00976
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00012 Hydrocortisone
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG00012 Hydrocortisone
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| Other DBs |
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| KCF data |
ATOM 35
1 C1z C 25.0600 -9.1000
2 C1y C 25.0600 -10.5000
3 C1z C 26.2500 -8.4000
4 C1x C 23.9400 -8.4700
5 C1a C 24.9900 -7.8400
6 C1y C 23.9400 -11.2000
7 C1x C 27.4400 -10.5000
8 C1x C 27.4400 -9.1000
9 C5a C 26.2500 -7.0700
10 O1a O 27.5800 -8.1200
11 C1y C 22.7500 -9.1700
12 C1y C 22.7500 -10.5000
13 C1x C 23.9400 -12.5300
14 C1b C 27.5100 -6.3700
15 O5a O 24.9900 -6.3700
16 O1a O 21.4900 -8.4700
17 C1z C 21.5600 -11.2000
18 C1x C 22.7500 -13.2300
19 O7a O 28.7000 -7.1400
20 C2y C 21.5600 -12.5300
21 C1x C 20.3700 -10.5000
22 C1a C 21.4900 -9.8700
23 C7a C 29.8900 -6.4400
24 C2x C 20.3700 -13.2300
25 C1x C 19.1800 -11.2000
26 C1b C 31.1500 -7.1400
27 O6a O 29.8900 -5.0400
28 C5x C 19.1800 -12.6000
29 C1b C 32.3400 -6.4400
30 O5x O 17.9900 -13.3000
31 C1y C 33.5300 -7.1400
32 C1x C 33.9500 -8.4700
33 C1x C 34.6500 -6.3000
34 C1x C 35.3500 -8.4700
35 C1x C 35.8400 -7.1400
BOND 39
1 1 2 1
2 1 3 1
3 1 4 1
4 1 5 1 #Up
5 2 6 1
6 2 7 1
7 3 8 1
8 3 9 1 #Up
9 3 10 1 #Down
10 4 11 1
11 6 12 1
12 6 13 1
13 9 14 1
14 9 15 2
15 11 16 1 #Up
16 12 17 1
17 13 18 1
18 14 19 1
19 17 20 1
20 17 21 1
21 17 22 1 #Up
22 19 23 1
23 20 24 2
24 21 25 1
25 23 26 1
26 23 27 2
27 24 28 1
28 26 29 1
29 28 30 2
30 29 31 1
31 31 32 1
32 31 33 1
33 32 34 1
34 33 35 1
35 7 8 1
36 11 12 1
37 18 20 1
38 25 28 1
39 34 35 1
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