| Entry |
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| Name |
Prednisolone tebutate (JAN/USP);
Hydeltra-TBA (TN) |
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| Formula |
C27H38O6
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| Exact mass |
458.2668
|
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| Mol weight |
458.587
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| Structure |
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| Simcomp |
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| Class |
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| Remark |
| Product (DG00093): | D00472<JP/US> D00980<JP/US> D00981<JP/US> D01239<JP> D03301<JP> |
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| Efficacy |
Anti-inflammatory, Glucocorticoid receptor agonist |
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Interaction |
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| Structure map |
| map07225 | Glucocorticoid and mineralocorticoid receptor agonists/antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A01 STOMATOLOGICAL PREPARATIONS
A01A STOMATOLOGICAL PREPARATIONS
A01AC Corticosteroids for local oral treatment
A01AC04 Prednisolone
D00982 Prednisolone tebutate (JAN/USP)
A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
A07E INTESTINAL ANTIINFLAMMATORY AGENTS
A07EA Corticosteroids acting locally
A07EA01 Prednisolone
D00982 Prednisolone tebutate (JAN/USP)
C CARDIOVASCULAR SYSTEM
C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
C05AA Corticosteroids
C05AA04 Prednisolone
D00982 Prednisolone tebutate (JAN/USP)
D DERMATOLOGICALS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AA Corticosteroids, weak (group I)
D07AA03 Prednisolone
D00982 Prednisolone tebutate (JAN/USP)
D07X CORTICOSTEROIDS, OTHER COMBINATIONS
D07XA Corticosteroids, weak, other combinations
D07XA02 Prednisolone
D00982 Prednisolone tebutate (JAN/USP)
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H02 CORTICOSTEROIDS FOR SYSTEMIC USE
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
H02AB Glucocorticoids
H02AB06 Prednisolone
D00982 Prednisolone tebutate (JAN/USP)
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AD Corticosteroids
R01AD02 Prednisolone
D00982 Prednisolone tebutate (JAN/USP)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01B ANTIINFLAMMATORY AGENTS
S01BA Corticosteroids, plain
S01BA04 Prednisolone
D00982 Prednisolone tebutate (JAN/USP)
S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
S01CB Corticosteroids/antiinfectives/mydriatics in combination
S01CB02 Prednisolone
D00982 Prednisolone tebutate (JAN/USP)
S02 OTOLOGICALS
S02B CORTICOSTEROIDS
S02BA Corticosteroids
S02BA03 Prednisolone
D00982 Prednisolone tebutate (JAN/USP)
S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
S03B CORTICOSTEROIDS
S03BA Corticosteroids
S03BA02 Prednisolone
D00982 Prednisolone tebutate (JAN/USP)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00093 Prednisolone
D00982 Prednisolone tebutate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D00982 Prednisolone tebutate (JAN/USP)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00093 Prednisolone
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| Other DBs |
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| KCF data |
ATOM 33
1 C2x C 5.5829 -11.2284
2 C5x C 5.5829 -12.5914
3 C2x C 6.7633 -13.2729
4 C2y C 7.9437 -12.5914
5 C1z C 7.9437 -11.2284
6 C2x C 6.7633 -10.5468
7 C1x C 9.1241 -13.2729
8 C1x C 10.3045 -12.5914
9 C1y C 10.3045 -11.2284
10 C1y C 9.1241 -10.5468
11 C1y C 11.4850 -10.5468
12 C1z C 11.4850 -9.1838
13 C1x C 10.3045 -8.5023
14 C1y C 9.1241 -9.1838
15 C1x C 13.8457 -10.5468
16 C1x C 13.8457 -9.1838
17 C1z C 12.6654 -8.5023
18 O5x O 4.4025 -13.2729
19 C1a C 7.9437 -9.8653
20 O1a O 7.9457 -8.5035
21 C1a C 11.4850 -7.8208
22 C5a C 12.6654 -6.7948
23 O1a O 13.8457 -7.8208
24 C1b C 13.8497 -6.1111
25 O5a O 11.4889 -6.1155
26 O7a O 15.0156 -6.7843
27 C7a C 16.2511 -6.0706
28 C1b C 17.4636 -6.7703
29 O6a O 16.2506 -4.6900
30 C1d C 18.6422 -6.0895
31 C1a C 19.8382 -6.7799
32 C1a C 18.6419 -4.6902
33 C1a C 18.6422 -7.4895
BOND 36
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 2
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 9 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 10 14 1
17 11 15 1
18 15 16 1
19 16 17 1
20 12 17 1
21 2 18 2
22 5 19 1 #Up
23 14 20 1 #Up
24 12 21 1 #Up
25 17 22 1 #Up
26 17 23 1 #Down
27 22 24 1
28 22 25 2
29 24 26 1
30 26 27 1
31 27 28 1
32 27 29 2
33 28 30 1
34 30 31 1
35 30 32 1
36 30 33 1
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