 | | DRUG: Triamcinolone acetonide | |
| Entry |
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| Name |
Triamcinolone acetonide (JP18/USP);
Azmacort (TN);
Kenalog (TN);
Nasacort (TN) |
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| Product |
KENALOG (Sun Pharmaceutical Industries), KENALOG-10 (A-S Medication Solutions), KENALOG-10 (E.R. Squibb & Sons), KENALOG-40 (A-S Medication Solutions), KENALOG-40 (A-S Medication Solutions), KENALOG-40 (Asclemed USA), KENALOG-40 (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (E.R. Squibb & Sons), TRIESENCE (Alcon Laboratories), XIPERE (Bausch & Lomb Incorporated), XIPERE (Clearside Biomedical), ZILRETTA (Pacira Pharmaceuticals) |
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| Generic |
KOURZEQ (MidAmerica Pharmaceuticals), ORALONE (Taro Pharmaceuticals U.S.A.), SCARZEN (Village Pharma LLC), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (Advanced Rx Pharmacy of Tennessee), TRIAMCINOLONE ACETONIDE (Amneal Pharmaceuticals LLC), TRIAMCINOLONE ACETONIDE (Amneal Pharmaceuticals LLC), TRIAMCINOLONE ACETONIDE (Amneal Pharmaceuticals LLC), TRIAMCINOLONE ACETONIDE (Ascend Laboratories), TRIAMCINOLONE ACETONIDE (Asclemed USA), TRIAMCINOLONE ACETONIDE (AuroMedics Pharma LLC), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Burel Pharmaceuticals), TRIAMCINOLONE ACETONIDE (CMP Pharma), TRIAMCINOLONE ACETONIDE (Cintex Services), TRIAMCINOLONE ACETONIDE (Cosette Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Cosette Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Cosette Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Cosette Pharmaceuticals), TRIAMCINOLONE ACETONIDE (DIRECTRX), TRIAMCINOLONE ACETONIDE (Direct Rx), TRIAMCINOLONE ACETONIDE (Direct_Rx), TRIAMCINOLONE ACETONIDE (E. Fougera & Co. a division of Fougera Pharmaceuticals), TRIAMCINOLONE ACETONIDE (E. Fougera & Co. a division of Fougera Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Encube Ethicals Private Limited), TRIAMCINOLONE ACETONIDE (Encube Ethicals Private Limited), TRIAMCINOLONE ACETONIDE (Encube Ethicals Private Limited), TRIAMCINOLONE ACETONIDE (Glenmark Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Glenmark Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Lake Erie Medical DBA Quality Care Products LLC), TRIAMCINOLONE ACETONIDE (Long Grove Pharmaceuticals), TRIAMCINOLONE ACETONIDE (MICRO LABS LIMITED), TRIAMCINOLONE ACETONIDE (Macleods Pharmaceuticals Limited), TRIAMCINOLONE ACETONIDE (Macleods Pharmaceuticals Limited), TRIAMCINOLONE ACETONIDE (Mayne Pharma), TRIAMCINOLONE ACETONIDE (Mylan Institutional LLC), TRIAMCINOLONE ACETONIDE (NorthStar Rx LLC), TRIAMCINOLONE ACETONIDE (NorthStar RxLLC), TRIAMCINOLONE ACETONIDE (NorthStar RxLLC), TRIAMCINOLONE ACETONIDE (NuCare Pharmaceuticals), TRIAMCINOLONE ACETONIDE (NuCare Pharmaceuticals), TRIAMCINOLONE ACETONIDE (NuCare Pharmaceuticals), TRIAMCINOLONE ACETONIDE (NuCare Pharmaceuticals), TRIAMCINOLONE ACETONIDE (NuCare Pharmaceuticals), TRIAMCINOLONE ACETONIDE (NuCare Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Padagis Israel Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Padagis Israel Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Padagis Israel Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Padagis Israel Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Preferred Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Preferred Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Preferred Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Preferred Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Preferred Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Preferred Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Preferred Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Preferred Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (QUAGEN PHARMACEUTICALS LLC), TRIAMCINOLONE ACETONIDE (QUAGEN PHARMACEUTICALS LLC), TRIAMCINOLONE ACETONIDE (REMEDYREPACK), TRIAMCINOLONE ACETONIDE (REMEDYREPACK), TRIAMCINOLONE ACETONIDE (REMEDYREPACK), TRIAMCINOLONE ACETONIDE (REMEDYREPACK), TRIAMCINOLONE ACETONIDE (REMEDYREPACK), TRIAMCINOLONE ACETONIDE (REMEDYREPACK), TRIAMCINOLONE ACETONIDE (RPK Pharmaceuticals), TRIAMCINOLONE ACETONIDE (RPK Pharmaceuticals), TRIAMCINOLONE ACETONIDE (RPK Pharmaceuticals), TRIAMCINOLONE ACETONIDE (RPK Pharmaceuticals), TRIAMCINOLONE ACETONIDE (RPK Pharmaceuticals), TRIAMCINOLONE ACETONIDE (RPK Pharmaceuticals), TRIAMCINOLONE ACETONIDE (RPK Pharmaceuticals), TRIAMCINOLONE ACETONIDE (RPK Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Rising Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Saptalis Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Strides Pharma Science Limited), TRIAMCINOLONE ACETONIDE (Taro Pharmaceuticals U.S.A.), TRIAMCINOLONE ACETONIDE (Taro Pharmaceuticals U.S.A.), TRIAMCINOLONE ACETONIDE (Taro Pharmaceuticals U.S.A.), TRIAMCINOLONE ACETONIDE (Teva Parenteral Medicines), TRIAMCINOLONE ACETONIDE (TruPharma), TRIAMCINOLONE ACETONIDE (medsource pharmaceuticals), TRIDERM (Crown Laboratories) |
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| Formula |
C24H31FO6
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| Exact mass |
434.2105
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| Mol weight |
434.4977
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| Structure |
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| Simcomp |
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| Class |
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
Dermatological agent
DG03243 Atopic dermatitis agent
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| Remark |
| Product (DG00010): | D00385<JP> D00983<JP/US> |
| Product (mixture): | D10299<US> |
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| Efficacy |
Antiasthmatic, Anti-inflammatory, Antirheumatic, Glucocorticoid receptor agonist |
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| Disease |
Asthma [DS: H00079] Atopic dermatitis [DS: H01358] Contact dermatitis [DS: H01357] Perennial or seasonal allergic rhinitis [DS: H01360] Bullous dermatitis herpetiformis [DS: H01362] Mycosis fungoides [DS: H01463] Pemphigus [DS: H01648] Erythema multiforme [DS: H01695] Stevens-Johnson syndrome [DS: H01694] Primary adrenocortical insufficiency [DS: H01598] Congenital adrenal hyperplasia [DS: H00216] Ulcerative colitis [DS: H01466] Acquired (autoimmune) hemolytic anemia [DS: H01585] Diamond-Blackfan anemia [DS: H00237] Pure red cell aplasia [DS: H01586] Thrombocytopenia [DS: H00978] Multiple sclerosis [DS: H01490] Temporal arteritis [DS: H01698] Nephrotic syndrome [DS: H01657] Pulmonary tuberculosis [DS: H00342] Ankylosing spondylitis [DS: H01674] Psoriatic arthritis [DS: H01507] Rheumatoid arthritis [DS: H00630] Juvenile rheumatoid arthritis [DS: H01672] Dermatomyositis and polymyositis [DS: H01604] Systemic lupus erythematosus [DS: H00080] |
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Interaction |
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| Structure map |
| map07225 | Glucocorticoid and mineralocorticoid receptor agonists/antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A01 STOMATOLOGICAL PREPARATIONS
A01A STOMATOLOGICAL PREPARATIONS
A01AC Corticosteroids for local oral treatment
A01AC01 Triamcinolone
D00983 Triamcinolone acetonide (JP18/USP) <JP/US>
C CARDIOVASCULAR SYSTEM
C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
C05AA Corticosteroids
C05AA12 Triamcinolone
D00983 Triamcinolone acetonide (JP18/USP) <JP/US>
D DERMATOLOGICALS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AB Corticosteroids, moderately potent (group II)
D07AB09 Triamcinolone
D00983 Triamcinolone acetonide (JP18/USP) <JP/US>
D07X CORTICOSTEROIDS, OTHER COMBINATIONS
D07XB Corticosteroids, moderately potent, other combinations
D07XB02 Triamcinolone
D00983 Triamcinolone acetonide (JP18/USP) <JP/US>
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H02 CORTICOSTEROIDS FOR SYSTEMIC USE
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
H02AB Glucocorticoids
H02AB08 Triamcinolone
D00983 Triamcinolone acetonide (JP18/USP) <JP/US>
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AD Corticosteroids
R01AD11 Triamcinolone
D00983 Triamcinolone acetonide (JP18/USP) <JP/US>
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
R03BA Glucocorticoids
R03BA06 Triamcinolone
D00983 Triamcinolone acetonide (JP18/USP) <JP/US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01B ANTIINFLAMMATORY AGENTS
S01BA Corticosteroids, plain
S01BA05 Triamcinolone
D00983 Triamcinolone acetonide (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
Dental and Oral Agents
Triamcinolone
D00983 Triamcinolone acetonide (JP18/USP)
Dermatological Agents
Dermatitis and Pruitus Agents
Glucocorticoids, Medium Potency
Triamcinolone
D00983 Triamcinolone acetonide (JP18/USP)
Glucocorticoids, High Potency
Triamcinolone
D00983 Triamcinolone acetonide (JP18/USP)
Hormonal Agents, Stimulant/Replacement/Modifying (Adrenal)
Triamcinolone
D00983 Triamcinolone acetonide (JP18/USP)
Inflammatory Bowel Disease Agents
Glucocorticoids
Triamcinolone
D00983 Triamcinolone acetonide (JP18/USP)
Ophthalmic Agents
Ophthalmic Anti-inflammatories
Glucocorticoids, Ophthalmic
Triamcinolone
D00983 Triamcinolone acetonide (JP18/USP)
Respiratory Tract/Pulmonary Agents
Anti-inflammatories, Inhaled Corticosteroids
Triamcinolone
D00983 Triamcinolone acetonide (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
13 Agents affecting sensory organs
131 Ophthalmic agents
1319 Others
D00983 Triamcinolone acetonide (JP18/USP)
2 Agents affecting individual organs
23 Digestive organ agents
239 Miscellaneous
2399 Others
D00983 Triamcinolone acetonide (JP18/USP)
24 Hormones
245 Adrenal hormone preparations
2454 Fluorinated adrenocorticotropic hormones
D00983 Triamcinolone acetonide (JP18/USP)
26 Epidermides
264 Analgesics, anti-itchings, astringents, anti-inflammatory agents
2646 Adrenocorticotropic hormones
D00983 Triamcinolone acetonide (JP18/USP)
Classification of Japanese OTC drugs [BR:br08313]
Agents for dental and stomatological use
74 Stomatitis remedies
D00983 Triamcinolone acetonide (JP18/USP)
Risk category of Japanese OTC drugs [BR:br08312]
Designated second-class OTC drugs
Inorganic and organic chemicals
Triamcinolone acetonide
D00983 Triamcinolone acetonide (JP18/USP)
Second-class OTC drugs
Inorganic and organic chemicals
Triamcinolone acetonide
D00983 Triamcinolone acetonide (JP18/USP)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00010 Triamcinolone
D00983 Triamcinolone acetonide
Dermatological agent
DG03243 Atopic dermatitis agent
D00983 Triamcinolone acetonide
Drug classes [BR:br08332]
Anti-inflammatory
DG01955 Corticosteroid
D00983 Triamcinolone acetonide
Dermatological agent
DG03243 Atopic dermatitis agent
D00983 Triamcinolone acetonide
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D00983 Triamcinolone acetonide (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00983 Triamcinolone acetonide
Topical steroids potency [br08317.html]
Classification in the USA
D00983
Classification in Japan
D00983
Rx-to-OTC switch list in the USA [br08315.html]
D00983
Rx-to-OTC switch list in Japan [br08314.html]
D00983
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00010 Triamcinolone
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| Other DBs |
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| KCF data |
ATOM 31
1 C2x C 18.6900 -28.5600
2 C5x C 18.6900 -29.8900
3 C2x C 19.8800 -30.5900
4 C2y C 21.0700 -29.8900
5 C1z C 21.0700 -28.5600
6 C2x C 19.8800 -27.8600
7 C1x C 22.2600 -30.5900
8 C1x C 23.4500 -29.8900
9 C1y C 23.4500 -28.5600
10 C1z C 22.2600 -27.8600
11 C1y C 24.5700 -27.8600
12 C1z C 24.5700 -26.5300
13 C1x C 23.4500 -25.8300
14 C1y C 22.2600 -26.5300
15 C1x C 26.9500 -27.8600
16 C1y C 26.9500 -26.5300
17 C1z C 25.7600 -25.8300
18 O5x O 17.5700 -30.5900
19 C1a C 21.0700 -27.1600
20 X F 22.2600 -29.1900
21 O1a O 21.0700 -25.8300
22 C1a C 24.5700 -25.1300
23 C5a C 25.7600 -24.2200
24 O2x O 27.1600 -24.9200
25 O5a O 26.9500 -23.5200
26 C1b C 24.5700 -23.5200
27 O1a O 23.4500 -24.2200
28 O2x O 28.3500 -26.5300
29 C1z C 28.5600 -24.9200
30 C1a C 29.9600 -24.9200
31 C1a C 28.5600 -23.5200
BOND 35
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 2
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 9 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 10 14 1
17 11 15 1
18 15 16 1
19 16 17 1
20 12 17 1
21 2 18 2
22 5 19 1 #Up
23 10 20 1 #Down
24 14 21 1 #Up
25 12 22 1 #Up
26 17 23 1 #Up
27 17 24 1 #Down
28 23 25 2
29 23 26 1
30 26 27 1
31 16 28 1 #Down
32 24 29 1
33 29 28 1
34 29 30 1
35 29 31 1
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