| Entry |
|
|---|
| Name |
Chloramphenicol palmitate (JP18/USP);
Chloromycetin palmitate (TN) |
|---|
| Formula |
C27H42Cl2N2O6
|
|---|
| Exact mass |
560.242
|
|---|
| Mol weight |
561.5382
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antibacterial
DG01576 Amphenicol type antibacterial
|
|---|
| Remark |
| Product (DG00399): | D00104<JP> D02185<JP/US> |
|
|---|
| Efficacy |
Antibacterial, Antirickettsial, Protein biosynthesis inhibitor |
|---|
| Comment |
Amphenicol derivative
Active form of prodrug: Chloramphenicol [DR: D00104]
|
|---|
| Target |
50S ribosomal subunit |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
D06A ANTIBIOTICS FOR TOPICAL USE
D06AX Other antibiotics for topical use
D06AX02 Chloramphenicol
D01072 Chloramphenicol palmitate (JP18/USP)
D10 ANTI-ACNE PREPARATIONS
D10A ANTI-ACNE PREPARATIONS FOR TOPICAL USE
D10AF Antiinfectives for treatment of acne
D10AF03 Chloramphenicol
D01072 Chloramphenicol palmitate (JP18/USP)
G GENITO URINARY SYSTEM AND SEX HORMONES
G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
G01AA Antibiotics
G01AA05 Chloramphenicol
D01072 Chloramphenicol palmitate (JP18/USP)
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01B AMPHENICOLS
J01BA Amphenicols
J01BA01 Chloramphenicol
D01072 Chloramphenicol palmitate (JP18/USP)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AA Antibiotics
S01AA01 Chloramphenicol
D01072 Chloramphenicol palmitate (JP18/USP)
S02 OTOLOGICALS
S02A ANTIINFECTIVES
S02AA Antiinfectives
S02AA01 Chloramphenicol
D01072 Chloramphenicol palmitate (JP18/USP)
S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
S03A ANTIINFECTIVES
S03AA Antiinfectives
S03AA08 Chloramphenicol
D01072 Chloramphenicol palmitate (JP18/USP)
Drug groups [BR:br08330]
Antibacterial
DG01576 Amphenicol type antibacterial
DG00399 Chloramphenicol
D01072 Chloramphenicol palmitate
Antimicrobials [BR:br08307]
Antibacterials
Protein biosynthesis inhibitor
Amphenicol
D01072 Chloramphenicol palmitate (JP18/USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01072 Chloramphenicol palmitate
Prodrugs [br08324.html]
D01072
Drug groups [BR:br08330]
Antibacterial
DG01576 Amphenicol type antibacterial
DG00399 Chloramphenicol
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Protein biosynthesis inhibitor
Amphenicol
DG00399 Chloramphenicol
Prodrugs [br08324.html]
DG00399
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 37
1 C8y C 12.6215 -14.5428
2 C1c C 12.6208 -15.9456
3 C8x C 11.4147 -13.8255
4 C8x C 13.8536 -13.8269
5 C1c C 13.8347 -16.6514
6 O1a O 11.4004 -16.6444
7 C8x C 11.4154 -12.4107
8 C8x C 13.8543 -12.4121
9 N1b N 15.0422 -15.9529
10 C1b C 13.8209 -18.0544
11 C8y C 12.6230 -11.7193
12 C5a C 16.2559 -16.6587
13 O7a O 12.6075 -18.7528
14 N2b N 12.6239 -10.3093 #+
15 C1c C 17.4694 -15.9671
16 O5a O 16.2552 -18.0617
17 O3a O 11.4171 -9.6106
18 O3a O 13.8327 -9.6003 #-
19 X Cl 18.6831 -16.6658
20 X Cl 17.4760 -14.5572
21 C7a C 12.6011 -20.1540
22 O6a O 11.3808 -20.8454
23 C1b C 13.8080 -20.8565
24 C1b C 15.0285 -20.1651
25 C1b C 16.2354 -20.8746
26 C1b C 17.4470 -20.1759
27 C1b C 18.6497 -20.8800
28 C1b C 19.8671 -20.1842
29 C1b C 21.0699 -20.8885
30 C1b C 22.2733 -20.1926
31 C1b C 23.4760 -20.8898
32 C1b C 24.6725 -20.1940
33 C1b C 25.8822 -20.8912
34 C1b C 27.0787 -20.1953
35 C1b C 28.2883 -20.8925
36 C1b C 29.4848 -20.1967
37 C1a C 30.6810 -20.8929
BOND 37
1 15 19 1
2 15 20 1
3 8 11 1
4 13 21 1
5 1 2 1
6 21 22 2
7 1 3 2
8 21 23 1
9 1 4 1
10 23 24 1
11 2 5 1
12 24 25 1
13 2 6 1 #Down
14 25 26 1
15 3 7 1
16 26 27 1
17 4 8 2
18 27 28 1
19 5 9 1
20 28 29 1
21 5 10 1
22 29 30 1
23 7 11 2
24 30 31 1
25 9 12 1
26 31 32 1
27 10 13 1
28 32 33 1
29 11 14 1
30 33 34 1
31 12 15 1
32 34 35 1
33 12 16 2
34 35 36 1
35 14 17 2
36 36 37 1
37 14 18 1
|
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