 | | DRUG: Tranexamic acid | |
| Entry |
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| Name |
Tranexamic acid (JP18/USP/INN);
Cyklokapron (TN);
Rikavarin (TN);
Transamin (TN) |
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| Product |
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| Generic |
TRANEXAMIC ACID (A-S Medication Solutions), TRANEXAMIC ACID (ANI Pharmaceuticals), TRANEXAMIC ACID (Actavis Pharma), TRANEXAMIC ACID (Almaject), TRANEXAMIC ACID (American Health Packaging), TRANEXAMIC ACID (American Regent), TRANEXAMIC ACID (Amneal Pharmaceuticals LLC), TRANEXAMIC ACID (Amring Pharmaceuticals), TRANEXAMIC ACID (Apotex Corp.), TRANEXAMIC ACID (Armas Pharmaceuticals), TRANEXAMIC ACID (Armas Pharmaceuticals), TRANEXAMIC ACID (Athenex Pharmaceutical Division), TRANEXAMIC ACID (Athenex Pharmaceutical Division), TRANEXAMIC ACID (Aurobindo Pharma Limited), TRANEXAMIC ACID (AvPAK), TRANEXAMIC ACID (Baxter Healthcare Corporation), TRANEXAMIC ACID (Bryant Ranch Prepack), TRANEXAMIC ACID (Bryant Ranch Prepack), TRANEXAMIC ACID (Bryant Ranch Prepack), TRANEXAMIC ACID (Bryant Ranch Prepack), TRANEXAMIC ACID (Caplin Steriles Limited), TRANEXAMIC ACID (Eugia US LLC), TRANEXAMIC ACID (Fresenius Kabi USA), TRANEXAMIC ACID (Gland Pharma Limited), TRANEXAMIC ACID (HF Acquisition Co LLC), TRANEXAMIC ACID (Heritage Pharmaceuticals Labs Inc. d/b/a Avet Pharmaceuticals Labs), TRANEXAMIC ACID (Heritage Pharmaceuticals Labs Inc. d/b/a Avet Pharmaceuticals Labs), TRANEXAMIC ACID (Methapharm), TRANEXAMIC ACID (Micro Labs Limited), TRANEXAMIC ACID (Mylan Institutional LLC), TRANEXAMIC ACID (Provepharm), TRANEXAMIC ACID (Sagent Pharmaceuticals), TRANEXAMIC ACID (XGen Pharmaceuticals DJB), TRANEXAMIC ACID (Zydus Lifesciences Limited), TRANEXAMIC ACID (Zydus Pharmaceuticals (USA)), TRANEXAMIC ACID IN SODIUM CHLORIDE (Amneal Pharmaceuticals Private Limited) |
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| Formula |
C8H15NO2
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| Exact mass |
157.1103
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| Mol weight |
157.2102
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| Structure |
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| Simcomp |
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| Class |
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| Remark |
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| Efficacy |
Antifibrinolytic, Anti-inflammatory, Plasmin inhibitor |
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| Disease |
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| Target |
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| Pathway |
| hsa04610 | Complement and coagulation cascades |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
B BLOOD AND BLOOD FORMING ORGANS
B02 ANTIHEMORRHAGICS
B02A ANTIFIBRINOLYTICS
B02AA Amino acids
B02AA02 Tranexamic acid
D01136 Tranexamic acid (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Blood Products and Modifiers
Hemostasis Agents
Tranexamic Acid
D01136 Tranexamic acid (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
3 Agents affecting metabolism
33 Blood and body fluid agents
332 Hemostatics
3327 Antiplasmins
D01136 Tranexamic acid (JP18/USP/INN)
4 Agents affecting cellular function
44 Allergic agents
449 Miscellaneous
4490 Miscellaneous
D01136 Tranexamic acid (JP18/USP/INN)
Classification of Japanese OTC drugs [BR:br08313]
Nourishing tonics and health supplements
38 Vitamin C based drugs
D01136 Tranexamic acid (JP18/USP/INN)
Agents for dental and stomatological use
73 Stomatologic and laryngologic remedies (incl. toche without claims for cough and phlegm)
D01136 Tranexamic acid (JP18/USP/INN)
Risk category of Japanese OTC drugs [BR:br08312]
First-class OTC drugs
Inorganic and organic chemicals
Tranexamic acid
D01136 Tranexamic acid (JP18/USP/INN)
Third-class OTC drugs
Inorganic and organic chemicals
Tranexamic acid
D01136 Tranexamic acid (JP18/USP/INN)
Drug groups [BR:br08330]
Blood modifier agent
DG02016 Hemostatics
DG02012 Antifibrinolytic
DG01540 Plasmin inhibitor
D01136 Tranexamic acid
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Serine peptidases
PLG
D01136 Tranexamic acid (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01136 Tranexamic acid
D01136 Tranexamic acid tablets
D01136 Tranexamic acid capsules
D01136 Tranexamic acid injection
Rx-to-OTC switch list in Japan [br08314.html]
D01136
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| Other DBs |
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| KCF data |
ATOM 11
1 C1x C 23.7617 -17.2548
2 C1x C 23.7617 -18.6550
3 C1y C 24.9772 -19.3552
4 C1x C 26.1856 -18.6550
5 C1x C 26.1856 -17.2548
6 C1y C 24.9772 -16.5547
7 C6a C 24.9789 -15.1545
8 O6a O 26.1924 -14.4560
9 O6a O 23.7673 -14.4529
10 C1b C 24.9789 -20.7554
11 N1a N 26.1924 -21.4540
BOND 11
1 5 6 1
2 6 1 1
3 6 7 1
4 1 2 1
5 7 8 1
6 2 3 1
7 7 9 2
8 3 4 1
9 3 10 1 #Down
10 4 5 1
11 10 11 1
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