| Entry |
|
|---|
| Name |
Cefepime hydrochloride (USP);
Cefepime dihydrochloride hydrate (JP18);
Maxipime (TN) |
|---|
| Product |
|
|---|
| Generic |
CEFEPIME (Apotex Corp.), CEFEPIME (Apotex Corp.), CEFEPIME (Apotex Corp.), CEFEPIME (Fresenius Kabi USA), CEFEPIME (Hospira), CEFEPIME (Qilu Pharmaceutical), CEFEPIME (SAMSON MEDICAL TECHNOLOGIES LLC), CEFEPIME (Sagent Pharmaceuticals), CEFEPIME (Sagent Pharmaceuticals), CEFEPIME (WG Critical Care), CEFEPIME (WG Critical Care), CEFEPIME HYDROCHLORIDE (Xellia Pharmaceuticals USA LLC) |
|---|
| Formula |
C19H25N6O5S2. HCl. Cl. H2O
|
|---|
| Exact mass |
570.0889
|
|---|
| Mol weight |
571.4982
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
| Therapeutic category: | 6132 |
| Product (DG00586): | D01157<JP/US> |
| Product (mixture): | D12818<US> |
|
|---|
| Efficacy |
Antibacterial, Cell wall biosynthesis inhibitor |
|---|
| Disease |
Uncomplicated and complicated urinary tract infections [DS: H01176] |
|---|
| Target |
penicillin binding protein |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01D OTHER BETA-LACTAM ANTIBACTERIALS
J01DE Fourth-generation cephalosporins
J01DE01 Cefepime
D01157 Cefepime hydrochloride (USP) <JP/US>
USP drug classification [BR:br08302]
Antibacterials
Beta-lactam, Cephalosporins
Cefepime
D01157 Cefepime hydrochloride (USP)
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
61 Antibiotics
613 Acting mainly on gram-positive and gram-negative bacteria
6132 Cephem antibioitics
D01157 Cefepime hydrochloride (USP); Cefepime dihydrochloride hydrate (JP18)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00586 Cefepime
D01157 Cefepime hydrochloride
DG01777 Fourth-generation cephalosporin
DG00586 Cefepime
D01157 Cefepime hydrochloride
DG01804 Oxyimino beta-lactam
DG00586 Cefepime
D01157 Cefepime hydrochloride
Drug classes [BR:br08332]
Antibacterial
DG01488 Cephem
D01157 Cefepime hydrochloride
Antimicrobials [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Fourth-generation cephalosporin
D01157 Cefepime hydrochloride (USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01157 Cefepime dihydrochloride hydrate
D01157 Cefepime dihydrochloride for injection
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00586 Cefepime
DG01777 Fourth-generation cephalosporin
DG00586 Cefepime
DG01804 Oxyimino beta-lactam
DG00586 Cefepime
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Fourth-generation cephalosporin
DG00586 Cefepime
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 35
1 X Cl 19.3672 -22.6156
2 X Cl 29.6799 -18.2084 #-
3 O0 O 22.4824 -22.5456
4 C1y C 26.0672 -18.8627
5 N1y N 26.0672 -20.2534
6 C2y C 27.2717 -20.9487
7 C2y C 28.4761 -20.2534
8 C1x C 28.4761 -18.8627
9 S2x S 27.2717 -18.1673
10 C1y C 24.6764 -18.8627
11 C5x C 24.6764 -20.2534
12 N1b N 23.4722 -18.1673
13 C5a C 22.2677 -18.8627
14 O5a O 22.2677 -20.2534
15 O5x O 23.4722 -20.9487
16 C2c C 21.0633 -18.1673
17 C1b C 29.6990 -20.9598
18 C8y C 19.8396 -18.8743
19 N2y N 30.9084 -20.2618 #+
20 C8x C 18.7080 -18.0429
21 S2x S 17.5629 -18.8608
22 C8y C 17.9869 -20.2027
23 N5x N 19.3940 -20.2140
24 N2b N 21.0632 -16.7553
25 C6a C 27.2717 -22.3560
26 O6a O 28.4867 -23.0575
27 O6a O 26.0583 -23.0567
28 C1x C 30.9086 -18.8509
29 C1x C 32.2501 -20.6980
30 C1x C 33.0795 -19.5567
31 C1x C 32.2504 -18.4151
32 C1a C 30.9084 -21.6640
33 N1a N 17.1436 -21.3437
34 O2a O 22.2916 -16.0462
35 C1a C 22.2922 -14.6304
BOND 35
1 4 5 1
2 5 6 1
3 6 7 2
4 7 8 1
5 8 9 1
6 4 9 1
7 4 10 1
8 10 11 1
9 5 11 1
10 10 12 1 #Up
11 12 13 1
12 13 14 2
13 11 15 2
14 13 16 1
15 7 17 1
16 16 18 1
17 17 19 1
18 18 20 2
19 20 21 1
20 21 22 1
21 22 23 2
22 18 23 1
23 16 24 2
24 6 25 1
25 25 26 1
26 25 27 2
27 19 28 1
28 19 29 1
29 29 30 1
30 30 31 1
31 28 31 1
32 19 32 1
33 22 33 1
34 24 34 1
35 34 35 1
|
|---|
