| Entry |
|
|---|
| Name |
Remifentanil hydrochloride (JAN/USAN);
Ultiva (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C20H28N2O5. HCl
|
|---|
| Exact mass |
412.1765
|
|---|
| Mol weight |
412.9077
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
| Therapeutic category: | 8219 |
| Product (DG00795): | D01177<JP/US> |
|
|---|
| Efficacy |
Analgesic, Opioid receptor agonist |
|---|
| Comment |
opioid
Phenylpiperidine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07224 | Opioid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N01 ANESTHETICS
N01A ANESTHETICS, GENERAL
N01AH Opioid anesthetics
N01AH06 Remifentanil
D01177 Remifentanil hydrochloride (JAN/USAN) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
8 Narcotics
82 Non-alkaloidal narcotics
821 Synthetic narcotics
8219 Others
D01177 Remifentanil hydrochloride (JAN/USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG02030 Anesthetics
DG02027 General anesthetics
DG02026 Opioid anesthetics
DG00795 Remifentanil
D01177 Remifentanil hydrochloride
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG00795 Remifentanil
D01177 Remifentanil hydrochloride
Analgesic
DG01984 Opioid analgesics
DG00795 Remifentanil
D01177 Remifentanil hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D01177 Remifentanil hydrochloride (JAN/USAN) <JP/US>
New drug approvals in Japan [br08318.html]
Drugs with new active ingredients
D01177
Drug groups [BR:br08330]
Neuropsychiatric agent
DG02030 Anesthetics
DG02027 General anesthetics
DG02026 Opioid anesthetics
DG00795 Remifentanil
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG00795 Remifentanil
Analgesic
DG01984 Opioid analgesics
DG00795 Remifentanil
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 28
1 X Cl 29.6535 -25.6624
2 C8x C 16.9400 -27.3700
3 C8x C 16.9400 -28.8400
4 C8x C 18.1300 -29.5400
5 C8x C 19.3900 -28.8400
6 C8y C 19.3900 -27.3700
7 C8x C 18.1300 -26.6000
8 N1c N 20.6500 -26.6000
9 C1z C 21.9100 -27.3700
10 C1x C 21.9100 -28.8400
11 C1x C 23.1000 -29.5400
12 N1y N 24.3600 -28.8400
13 C1x C 24.3600 -27.3700
14 C1x C 23.1000 -26.6000
15 C1b C 25.6200 -29.5400
16 C1b C 26.8100 -28.8400
17 C7a C 28.0700 -29.5400
18 C5a C 20.6500 -25.2000
19 O5a O 19.3900 -24.5000
20 C1b C 21.9100 -24.5000
21 C1a C 23.1000 -25.2000
22 C7a C 21.1400 -28.5600
23 O7a O 29.3300 -28.8400
24 C1a C 30.5200 -29.5400
25 O6a O 28.0000 -30.9400
26 O7a O 21.1400 -29.9600
27 C1a C 19.9276 -30.6600
28 O6a O 19.9373 -28.1635
BOND 28
1 2 3 2
2 3 4 1
3 4 5 2
4 5 6 1
5 6 7 2
6 2 7 1
7 6 8 1
8 8 9 1
9 9 10 1
10 10 11 1
11 11 12 1
12 12 13 1
13 13 14 1
14 9 14 1
15 12 15 1
16 15 16 1
17 16 17 1
18 8 18 1
19 18 19 2
20 18 20 1
21 20 21 1
22 9 22 1
23 17 23 1
24 23 24 1
25 17 25 2
26 22 26 1
27 26 27 1
28 22 28 2
|
|---|
