KEGG   DRUG: Prothionamide
Entry
D01195                      Drug                                   
Name
Prothionamide (JP18);
Protionamide (INN);
Trevintix (TN)
  Abbr
PTO
Formula
C9H12N2S
Exact mass
180.0721
Mol weight
180.27
Structure
Simcomp
Class
Antibacterial
 DG01966  Antitubercular
  DG01788  Thiocarbamide derivative
Remark
ATC code: J04AD01
Efficacy
Antibacterial (tuberculostatic)
Comment
Thiocarbamide derivative
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J04 ANTIMYCOBACTERIALS
   J04A DRUGS FOR TREATMENT OF TUBERCULOSIS
    J04AD Thiocarbamide derivatives
     J04AD01 Protionamide
      D01195  Prothionamide (JP18)
Drug groups [BR:br08330]
 Antibacterial
  DG01966  Antitubercular
   DG01788  Thiocarbamide derivative
    D01195  Prothionamide
Antimicrobials [BR:br08307]
 Antibacterials
  Other antibacterials
   Mycolic acid biosynthesis inhibitor
    D01195  Prothionamide (JP18)
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Other antibacterials
   Mycolic acid biosynthesis inhibitor
    D01195  Prothionamide (JP17)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01195  Prothionamide
Other DBs
CAS: 14222-60-7
PubChem: 7848258
ChEBI: 32066
LigandBox: D01195
NIKKAJI: J3.442H
KCF data

ATOM        12
            1   C8y C    27.1925  -18.4288
            2   C8x C    25.9796  -19.1285
            3   C8x C    27.1925  -17.0294
            4   C2c C    28.3994  -19.1285
            5   C8y C    24.7610  -18.4288
            6   C8x C    25.9796  -16.3240
            7   N1a N    29.6062  -18.4288
            8   S0  S    28.3878  -20.5278
            9   N5x N    24.7610  -17.0294
            10  C1b C    23.5483  -19.1285
            11  C1b C    22.3355  -18.4288
            12  C1a C    21.1277  -19.1268
BOND        12
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 2
            5     3   6 1
            6     4   7 1
            7     4   8 2
            8     5   9 1
            9     5  10 1
            10   10  11 1
            11    6   9 2
            12   11  12 1

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