| Entry |
|
|---|
| Name |
Trapidil (JP18/INN);
Rocornal (TN) |
|---|
| Formula |
C10H15N5
|
|---|
| Exact mass |
205.1327
|
|---|
| Mol weight |
205.2596
|
|---|
| Structure |
|
|---|
| Class |
Blood modifier agent
DG01950 Antithrombotic agent
DG01712 Antiplatelet agent
DG01516 Thromboxane A2 synthase inhibitor
|
|---|
| Remark |
| Therapeutic category: | 2171 |
|
|---|
| Efficacy |
Vasodilator, Phosphodiesterase inhibitor |
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C01 CARDIAC THERAPY
C01D VASODILATORS USED IN CARDIAC DISEASES
C01DX Other vasodilators used in cardiac diseases
C01DX11 Trapidil
D01220 Trapidil (JP18/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
217 Vasodilators
2171 Coronary dilators
D01220 Trapidil (JP18/INN)
Drug groups [BR:br08330]
Blood modifier agent
DG01950 Antithrombotic agent
DG01712 Antiplatelet agent
DG01516 Thromboxane A2 synthase inhibitor
D01220 Trapidil
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Phosphodiesterases
PDE
D01220 Trapidil (JP18/INN) <JP>
Isomerases (EC5)
Thromboxane-A synthase
TBXAS1 (CYP5A1)
D01220 Trapidil (JP18/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01220 Trapidil
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 15
1 C8y C 12.3900 -17.5700
2 N4y N 12.3900 -16.1700
3 C8y C 11.1776 -15.4700
4 C8x C 9.9651 -16.1700
5 C8y C 9.9651 -17.5700
6 N5x N 11.1776 -18.2700
7 N5x N 13.7215 -18.0026
8 C8x C 14.5444 -16.8700
9 N5x N 13.7215 -15.7374
10 N1c N 11.1776 -14.0702
11 C1b C 12.4068 -13.3603
12 C1b C 9.9820 -13.3798
13 C1a C 8.7948 -14.0652
14 C1a C 13.6108 -14.0554
15 C1a C 8.7340 -18.2810
BOND 16
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 1 7 2
8 7 8 1
9 8 9 2
10 2 9 1
11 3 10 1
12 10 11 1
13 10 12 1
14 12 13 1
15 11 14 1
16 5 15 1
|
|---|
