| Entry |
|
|---|
| Name |
Sulpiride (JP18/USAN/INN);
Dogmatyl (TN) |
|---|
| Formula |
C15H23N3O4S
|
|---|
| Exact mass |
341.1409
|
|---|
| Mol weight |
341.4258
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG03200 Antipsychotic agent
DG01941 Benzamide antipsychotic
|
|---|
| Remark |
|
|---|
| Efficacy |
Antidepressant, Antipsychotic, Anti-ulcerative, Dopamine receptor antagonist |
|---|
| Comment |
Benzamide derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07213 | Dopamine receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AL Benzamides
N05AL01 Sulpiride
D01226 Sulpiride (JP18/USAN/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
117 Psychotropics
1179 Others
D01226 Sulpiride (JP18/USAN/INN)
2 Agents affecting individual organs
23 Digestive organ agents
232 Peptic ulcer agents
2329 Others
D01226 Sulpiride (JP18/USAN/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
D01226 Sulpiride
DG03200 Antipsychotic agent
DG01941 Benzamide antipsychotic
D01226 Sulpiride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D01226 Sulpiride (JP18/USAN/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01226 Sulpiride
D01226 Sulpiride tablets
D01226 Sulpiride capsules
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 23
1 C8y C 11.2700 -23.1000
2 C8x C 11.2700 -21.7000
3 C8x C 12.4600 -21.0000
4 C8y C 13.7200 -21.7000
5 C8y C 13.7200 -23.1000
6 C8x C 12.4600 -23.8000
7 C5a C 14.9100 -23.8000
8 N1b N 16.1000 -23.1000
9 O5a O 14.9100 -25.2000
10 O2a O 14.9100 -21.0000
11 C1b C 17.2900 -23.8000
12 C1y C 18.4800 -23.1000
13 C1x C 18.9000 -21.7700
14 C1x C 20.3000 -21.7700
15 C1x C 20.7900 -23.1000
16 N1y N 19.6700 -23.9400
17 C1b C 19.6700 -25.3400
18 C1a C 20.8600 -26.0400
19 S4a S 10.0800 -23.8000
20 N1a N 8.8200 -24.5000
21 O3c O 9.3800 -22.6100
22 O3c O 11.0600 -24.7800
23 C1a C 14.9100 -19.6000
BOND 24
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 7 9 2
10 4 10 1
11 8 11 1
12 11 12 1
13 12 13 1
14 13 14 1
15 14 15 1
16 15 16 1
17 12 16 1
18 16 17 1
19 17 18 1
20 1 19 1
21 19 20 1
22 19 21 2
23 19 22 2
24 10 23 1
|
|---|
