KEGG   DRUG: Piroheptine hydrochloride
Entry
D01231                      Drug                                   
Name
Piroheptine hydrochloride (JAN);
Trimol (TN)
Formula
C22H25N. HCl
Exact mass
339.1754
Mol weight
339.9015
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
  DG01745  Anticholinergic antiparkinson agent
 DG01967  Antiparkinson agent
Remark
Therapeutic category: 1169
Chemical structure group: DG01272
Product (DG01272): D01231<JP>
Efficacy
Antiparkinsonian, Muscarinic acetylcholine receptor antagonist
Target
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
Interaction
Structure map
map07057  Antiparkinsonian agents
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   116  Antiparkinsonian agents
    1169  Others
     D01231  Piroheptine hydrochloride (JAN)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG01491  Muscarinic cholinergic receptor antagonist
   DG01745  Anticholinergic antiparkinson agent
    DG01272  Piroheptine
     D01231  Piroheptine hydrochloride
  DG01967  Antiparkinson agent
   DG01272  Piroheptine
    D01231  Piroheptine hydrochloride
Drug classes [BR:br08332]
 Neuropsychiatric agent
  DG01967  Antiparkinson agent
   D01231  Piroheptine hydrochloride
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM
     D01231  Piroheptine hydrochloride (JAN) <JP>
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG01491  Muscarinic cholinergic receptor antagonist
   DG01745  Anticholinergic antiparkinson agent
    DG01272  Piroheptine
  DG01967  Antiparkinson agent
   DG01272  Piroheptine
Other DBs
CAS: 16378-22-6
PubChem: 7848294
ChEBI: 32018
LigandBox: D01231
NIKKAJI: J327.463B
KCF data

ATOM        24
            1   C1x C    16.4252  -11.3873
            2   C8y C    15.5808  -10.2747
            3   C8y C    15.9169   -8.9142
            4   C2y C    17.1814   -8.3345
            5   C1x C    17.8348  -11.4126
            6   C8y C    18.4383   -8.9585
            7   C8y C    18.7256  -10.3310
            8   C8x C    14.9070   -7.9431
            9   C8x C    13.5614   -8.3323
            10  C8x C    13.2253   -9.6928
            11  C8x C    14.2351  -10.6636
            12  C8x C    20.0604  -10.7693
            13  C8x C    21.1075   -9.8323
            14  C8x C    20.8204   -8.4598
            15  C8x C    19.4853   -8.0215
            16  C2y C    17.1331   -6.9558
            17  C1y C    18.2593   -6.0760
            18  N1y N    17.7706   -4.7330
            19  C1x C    16.3423   -4.7828
            20  C1x C    15.9484   -6.1566
            21  C1a C    19.6187   -6.4657
            22  C1b C    18.4279   -3.4969
            23  C1a C    19.8279   -3.4969
            24  X   Cl   24.0826   -9.5529
BOND        26
            1     3   4 1
            2     1   5 1
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     3   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 2
            13    7  12 2
            14   12  13 1
            15   13  14 2
            16   14  15 1
            17    6  15 2
            18    4  16 2
            19   16  17 1
            20   17  18 1
            21   18  19 1
            22   19  20 1
            23   16  20 1
            24   17  21 1
            25   18  22 1
            26   22  23 1

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