| Entry |
|
|---|
| Name |
Bufexamac (JAN/INN);
Anderm (TN) |
|---|
| Formula |
C12H17NO3
|
|---|
| Exact mass |
223.1208
|
|---|
| Mol weight |
223.2683
|
|---|
| Structure |
|
|---|
| Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01906 Anti-inflammatory drug, acetic acid derivatives
|
|---|
| Remark |
|
|---|
| Efficacy |
Anti-inflammatory, COX inhibitor |
|---|
| Comment |
Nonsteroidal anti-inflammatory drug (NSAID)
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
M01AB Acetic acid derivatives and related substances
M01AB17 Bufexamac
D01271 Bufexamac (JAN/INN)
M02 TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02A TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02AA Antiinflammatory preparations, non-steroids for topical use
M02AA09 Bufexamac
D01271 Bufexamac (JAN/INN)
Classification of Japanese OTC drugs [BR:br08313]
Agents for integumentary system
57 Analgesic, antipruritic, astringent, and anti-inflammatory remedies (incl. gel patches)
D01271 Bufexamac (JAN/INN)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Bufexamac
D01271 Bufexamac (JAN/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01906 Anti-inflammatory drug, acetic acid derivatives
D01271 Bufexamac
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D01271 Bufexamac (JAN/INN)
PTGS2 (COX2)
D01271 Bufexamac (JAN/INN)
|
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| Other DBs |
|
|---|
| KCF data |
ATOM 16
1 C8x C 28.3500 -24.0800
2 C8y C 28.3500 -25.4800
3 C8x C 29.6100 -26.1800
4 C8x C 30.8000 -25.4800
5 C8y C 30.8000 -24.0800
6 C8x C 29.6100 -23.3800
7 C1b C 31.9900 -23.3800
8 C5a C 33.1800 -24.0800
9 N1b N 34.4400 -23.3800
10 O5a O 33.1800 -25.4800
11 O1b O 35.6300 -24.0800
12 O2a O 27.1600 -26.1800
13 C1b C 25.9700 -25.4800
14 C1b C 24.7100 -26.1800
15 C1b C 23.5200 -25.4800
16 C1a C 22.3300 -26.1800
BOND 16
1 7 8 1
2 2 3 2
3 8 9 1
4 3 4 1
5 8 10 2
6 4 5 2
7 9 11 1
8 5 6 1
9 2 12 1
10 6 1 2
11 12 13 1
12 13 14 1
13 5 7 1
14 14 15 1
15 1 2 1
16 15 16 1
|
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