| Entry |
|
|---|
| Name |
Flutoprazepam (JP18/INN);
Restas (TN) |
|---|
| Formula |
C19H16ClFN2O
|
|---|
| Exact mass |
342.0935
|
|---|
| Mol weight |
342.7945
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01567 GABA-A receptor agonist
DG01914 Anxiolytics, benzodiazepine derivatives
|
|---|
| Efficacy |
Antianxiety |
|---|
| Comment |
Benzodiazepine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07230 | GABA-A receptor agonists/antagonists |
|
|---|
| Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01567 GABA-A receptor agonist
D01279 Flutoprazepam
DG01914 Anxiolytics, benzodiazepine derivatives
D01279 Flutoprazepam
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
GABA (ionotropic)
GABR
D01279 Flutoprazepam (JP18/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01279 Flutoprazepam
D01279 Flutoprazepam tablets
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 24
1 C2y C 32.0600 -15.9600
2 C8y C 31.2200 -14.8400
3 C8y C 31.5700 -13.5100
4 N1y N 32.8300 -12.9500
5 N2x N 33.4600 -15.9600
6 C5x C 34.0900 -13.5800
7 C1x C 34.3700 -14.9100
8 C8x C 30.5200 -12.5300
9 C8x C 29.1900 -12.9500
10 C8y C 28.8400 -14.2800
11 C8x C 29.8900 -15.2600
12 O5x O 35.1400 -12.6000
13 X Cl 27.5100 -14.7000
14 C8y C 31.4300 -17.2200
15 C8x C 30.0300 -17.2200
16 C8x C 29.3300 -18.4100
17 C8x C 30.0300 -19.6700
18 C8x C 31.4300 -19.6700
19 C8y C 32.1300 -18.4100
20 X F 33.5300 -18.4100
21 C1b C 32.8300 -11.5500
22 C1y C 34.0900 -10.8500
23 C1x C 35.4900 -10.8500
24 C1x C 34.7900 -9.6600
BOND 27
1 3 4 1
2 1 5 2
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 3 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 2 11 2
13 6 12 2
14 10 13 1
15 1 14 1
16 14 15 1
17 15 16 2
18 16 17 1
19 17 18 2
20 18 19 1
21 14 19 2
22 19 20 1
23 4 21 1
24 21 22 1
25 22 23 1
26 23 24 1
27 24 22 1
|
|---|
