KEGG   DRUG: Cyclofenil
Entry
D01281                      Drug                                   
Name
Cyclofenil (JAN/INN);
Sexovid (TN)
Formula
C23H24O4
Exact mass
364.1675
Mol weight
364.4343
Structure
Simcomp
Class
Hormonal agent
 DG01619  Estrogen receptor antagonist/modulator
Remark
Therapeutic category: 2499
ATC code: G03GB01
Product: D01281<JP>
Efficacy
Ovulation inducing agent, Gonadotropin stimulant
Target
LHCGR [HSA:3973] [KO:K04248]
FSHR [HSA:2492] [KO:K04247]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04913  Ovarian steroidogenesis
hsa04917  Prolactin signaling pathway
Interaction
Structure map
map07226  Progesterone, androgen and estrogen receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
   G03G GONADOTROPINS AND OTHER OVULATION STIMULANTS
    G03GB Ovulation stimulants, synthetic
     G03GB01 Cyclofenil
      D01281  Cyclofenil (JAN/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  24  Hormones
   249  Miscellaneous
    2499  Others
     D01281  Cyclofenil (JAN/INN)
Drug groups [BR:br08330]
 Hormonal agent
  DG01619  Estrogen receptor antagonist/modulator
   D01281  Cyclofenil
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Follicle stimulating hormone
    FSHR
     D01281  Cyclofenil (JAN/INN) <JP>
   Lutropin-choriogonadotropic hormone
    LHCGR
     D01281  Cyclofenil (JAN/INN) <JP>
Other DBs
CAS: 2624-43-3
PubChem: 7848344
ChEBI: 31446
LigandBox: D01281
NIKKAJI: J3.393F
KCF data

ATOM        27
            1   C2y C    24.5158  -14.3724
            2   C2c C    24.5087  -15.7727
            3   C8y C    23.2925  -16.4668
            4   C8y C    25.7179  -16.4790
            5   C8x C    22.0843  -15.7608
            6   C8x C    20.8680  -16.4549
            7   C8y C    20.8610  -17.8553
            8   C8x C    22.0701  -18.5616
            9   C8x C    23.2864  -17.8675
            10  C8x C    25.7033  -17.8726
            11  C8x C    26.9125  -18.5789
            12  C8y C    28.1287  -17.8848
            13  C8x C    28.1358  -16.4844
            14  C8x C    26.9266  -15.7782
            15  O7a O    19.6447  -18.5492
            16  O7a O    29.3379  -18.5911
            17  C7a C    18.4354  -17.8429
            18  C1a C    17.2192  -18.5370
            19  O6a O    18.4426  -16.4425
            20  C7a C    30.5541  -17.8970
            21  C1a C    31.7634  -18.6033
            22  O6a O    30.4913  -16.4968
            23  C1x C    25.7320  -13.6783
            24  C1x C    25.7391  -12.2779
            25  C1x C    24.5299  -11.5716
            26  C1x C    23.3135  -12.2657
            27  C1x C    23.3066  -13.6661
BOND        29
            1    12  13 1
            2    13  14 2
            3    14   4 1
            4     5   6 1
            5     7  15 1
            6     6   7 2
            7    12  16 1
            8     7   8 1
            9    15  17 1
            10    8   9 2
            11   17  18 1
            12    9   3 1
            13   17  19 2
            14    2   3 1
            15   16  20 1
            16    1   2 2
            17   20  21 1
            18    2   4 1
            19   20  22 2
            20    3   5 2
            21    4  10 2
            22   10  11 1
            23   11  12 2
            24    1  23 1
            25   23  24 1
            26   24  25 1
            27   25  26 1
            28   26  27 1
            29   27   1 1

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (1)   
   KEGG PATHWAY (1)   
Drug (2)   
   KEGG DGROUP (1)   
   LigandBox (1)   
Chemical substance (3)   
   PubChem (1)   
   ChEBI (1)   
   NIKKAJI (1)   
Gene (4)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (2)   
All databases (14)   

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