| Entry |
|
|---|
| Name |
Medazepam (JP18/INN);
Pamnace (TN) |
|---|
| Formula |
C16H15ClN2
|
|---|
| Exact mass |
270.0924
|
|---|
| Mol weight |
270.7567
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01567 GABA-A receptor agonist
DG01914 Anxiolytics, benzodiazepine derivatives
|
|---|
| Remark |
| Therapeutic category: | 1124 |
| Product (DG00909): | D01292<JP> |
|
|---|
| Efficacy |
Antianxiety |
|---|
| Comment |
Benzodiazepine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07230 | GABA-A receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05B ANXIOLYTICS
N05BA Benzodiazepine derivatives
N05BA03 Medazepam
D01292 Medazepam (JP18/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
112 Hypnotics and sedatives, anxiolytics
1124 Benzodiazepins
D01292 Medazepam (JP18/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01567 GABA-A receptor agonist
DG00909 Medazepam
D01292 Medazepam
DG01914 Anxiolytics, benzodiazepine derivatives
DG00909 Medazepam
D01292 Medazepam
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
GABA (ionotropic)
GABR
D01292 Medazepam (JP18/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01292 Medazepam
Narcotics and psychotropics in Japan [br08308.html]
Psychotropics by Cabinet order Article 3 (78 substances)
D01292
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01567 GABA-A receptor agonist
DG00909 Medazepam
DG01914 Anxiolytics, benzodiazepine derivatives
DG00909 Medazepam
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 19
1 C2y C 19.9434 -14.3594
2 C8y C 19.1013 -13.2498
3 C8y C 19.4365 -11.8930
4 N1y N 20.6975 -11.3149
5 N2x N 21.3492 -14.3846
6 C1x C 21.9511 -11.9372
7 C1x C 22.2376 -13.3059
8 C8x C 18.4294 -10.9246
9 C8x C 17.0874 -11.3127
10 C8y C 16.7522 -12.6695
11 C8x C 17.7593 -13.6376
12 X Cl 15.3874 -13.0639
13 C8y C 19.3089 -15.6091
14 C8x C 17.9073 -15.6091
15 C8x C 17.2073 -16.8216
16 C8x C 17.9073 -18.0340
17 C8x C 19.3089 -18.0340
18 C8x C 20.0089 -16.8216
19 C1a C 20.7192 -9.9400
BOND 21
1 3 4 1
2 1 5 2
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 3 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 2 11 2
13 10 12 1
14 1 13 1
15 13 14 1
16 14 15 2
17 15 16 1
18 16 17 2
19 17 18 1
20 13 18 2
21 4 19 1
|
|---|
