| Entry |
|
|---|
| Name |
Azosemide (JP18/USAN/INN);
Diart (TN) |
|---|
| Formula |
C12H11ClN6O2S2
|
|---|
| Exact mass |
370.0073
|
|---|
| Mol weight |
370.8377
|
|---|
| Structure |
|
|---|
| Class |
|
|---|
| Remark |
| Therapeutic category: | 2139 |
|
|---|
| Efficacy |
Diuretic, Na-K-Cl cotransporter inhibitor |
|---|
| Comment |
loop diuretic
Sulfonamide derivative
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07017 | Sulfonamide derivatives - diuretics |
|
|---|
| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
213 Diuretics
2139 Others
D01323 Azosemide (JP18/USAN/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01690 Sulfonamide diuretic
DG01747 Furosemide type diuretic
D01323 Azosemide
DG01748 Loop diuretic
DG01747 Furosemide type diuretic
D01323 Azosemide
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC12
SLC12A1 (NKCC2)
D01323 Azosemide (JP18/USAN/INN) <JP>
SLC12A2 (NKCC1)
D01323 Azosemide (JP18/USAN/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01323 Azosemide
D01323 Azosemide tablets
|
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| Other DBs |
|
|---|
| KCF data |
ATOM 23
1 C8x C 17.6727 -20.0852
2 C8y C 18.1088 -18.7538
3 S2x S 16.9723 -17.9271
4 C8x C 15.8359 -18.7538
5 C8x C 16.2718 -20.0852
6 N5x N 20.1037 -14.6239
7 N5x N 18.7096 -14.6247
8 N5x N 18.2796 -15.9509
9 N4x N 19.4080 -16.7694
10 C8y C 20.5352 -15.9494
11 C8y C 21.7481 -16.6505
12 C8y C 21.7481 -18.0514
13 C8x C 22.9643 -18.7519
14 C8y C 24.1733 -18.0514
15 C8y C 24.1733 -16.6505
16 C8x C 22.9643 -15.9501
17 N1b N 20.5352 -18.7524
18 C1b C 19.3218 -18.0526
19 S4a S 25.3871 -15.9509
20 X Cl 25.3871 -18.7509
21 O3c O 26.5997 -16.6522
22 N1a N 26.5948 -15.2425
23 O3c O 24.1679 -15.2496
BOND 25
1 1 2 2
2 2 3 1
3 3 4 1
4 4 5 2
5 11 12 2
6 12 13 1
7 13 14 2
8 14 15 1
9 15 16 2
10 16 11 1
11 11 10 1
12 6 7 1
13 12 17 1
14 7 8 2
15 17 18 1
16 18 2 1
17 8 9 1
18 15 19 1
19 9 10 1
20 14 20 1
21 10 6 2
22 19 21 2
23 5 1 1
24 19 22 1
25 19 23 2
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