KEGG   DRUG: Fludiazepam
Entry
D01354                      Drug                                   
Name
Fludiazepam (JP18/INN);
Erispan (TN)
Formula
C16H12ClFN2O
Exact mass
302.0622
Mol weight
302.7307
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01567  GABA-A receptor agonist
 DG01914  Anxiolytics, benzodiazepine derivatives
Remark
Therapeutic category: 1124
ATC code: N05BA17
Efficacy
Antianxiety, Minor tranquilizer
Comment
Benzodiazepine derivative
Target
GABR [HSA:2554 2555 2556 2557 2558 2559 2560 2561 2562 2563 2564 2565 2566 2567 2568 55879] [KO:K05175 K05181 K05184 K05185 K05186 K05189 K05192]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04727  GABAergic synapse
Interaction
Structure map
map07230  GABA-A receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05B ANXIOLYTICS
    N05BA Benzodiazepine derivatives
     N05BA17 Fludiazepam
      D01354  Fludiazepam (JP18/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   112  Hypnotics and sedatives, anxiolytics
    1124  Benzodiazepins
     D01354  Fludiazepam (JP18/INN)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG01567  GABA-A receptor agonist
   D01354  Fludiazepam
  DG01914  Anxiolytics, benzodiazepine derivatives
   D01354  Fludiazepam
Target-based classification of drugs [BR:br08310]
 Ion channels
  Ligand-gated ion channels
   GABA (ionotropic)
    GABR
     D01354  Fludiazepam (JP18/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01354  Fludiazepam
  D01354  Fludiazepam tablets
Narcotics and psychotropics in Japan [br08308.html]
 Psychotropics by Cabinet order Article 3 (78 substances)
  D01354
Other DBs
CAS: 3900-31-0
PubChem: 7848417
ChEBI: 31618
LigandBox: D01354
NIKKAJI: J3.410J
KCF data

ATOM        21
            1   C2y C    13.7834  -11.9094
            2   C8y C    12.9413  -10.7998
            3   C8y C    13.2765   -9.4430
            4   N1y N    14.5375   -8.8649
            5   N2x N    15.1892  -11.9346
            6   C5x C    15.7911   -9.4872
            7   C1x C    16.0776  -10.8559
            8   C8x C    12.2694   -8.4746
            9   C8x C    10.9274   -8.8627
            10  C8y C    10.5922  -10.2195
            11  C8x C    11.5993  -11.1876
            12  O5x O    16.8352   -8.5528
            13  X   Cl    9.2274  -10.6139
            14  C8y C    13.1489  -13.1591
            15  C8x C    11.7473  -13.1591
            16  C8x C    11.0473  -14.3716
            17  C8x C    11.7473  -15.5840
            18  C8x C    13.1489  -15.5840
            19  C8y C    13.8489  -14.3716
            20  X   F    15.2598  -14.3717
            21  C1a C    14.5592   -7.4900
BOND        23
            1     3   4 1
            2     1   5 2
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     3   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 2
            13    6  12 2
            14   10  13 1
            15    1  14 1
            16   14  15 1
            17   15  16 2
            18   16  17 1
            19   17  18 2
            20   18  19 1
            21   14  19 2
            22   19  20 1
            23    4  21 1

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Ontology (6)   
   KEGG BRITE (6)   
Pathway (1)   
   KEGG PATHWAY (1)   
Drug (3)   
   KEGG DGROUP (2)   
   LigandBox (1)   
Chemical substance (4)   
   PubChem (1)   
   ChEBI (1)   
   HMDB (1)   
   NIKKAJI (1)   
Gene (23)   
   KEGG ORTHOLOGY (7)   
   KEGG GENES (16)   
All databases (37)   

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