| Entry |
|
|---|
| Name |
Bezafibrate (JP18/USAN/INN);
Bezatol SR (TN) |
|---|
| Formula |
C19H20ClNO4
|
|---|
| Exact mass |
361.1081
|
|---|
| Mol weight |
361.8194
|
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| Structure |
|
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| Class |
|
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| Remark |
| Therapeutic category: | 2183 |
|
|---|
| Efficacy |
Antihyperlipidemic, Triglyceride synthesis inhibitor, Peroxisome proliferator-activated receptor (PPAR) alpha agonist |
|---|
| Comment |
Clofibrate derivative
|
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| Target |
|
|---|
| Pathway |
| hsa04920 | Adipocytokine signaling pathway |
|
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| Interaction |
|
|---|
| Structure map |
| map07222 | Peroxisome proliferator-activated receptor (PPAR) agonists |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C10 LIPID MODIFYING AGENTS
C10A LIPID MODIFYING AGENTS, PLAIN
C10AB Fibrates
C10AB02 Bezafibrate
D01366 Bezafibrate (JP18/USAN/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
218 Hyperlipidemia agents
2183 Clofibrates
D01366 Bezafibrate (JP18/USAN/INN)
Drug groups [BR:br08330]
Hypolipidemic agent
DG01946 Hypolipidemic agent
DG01733 PPAR alpha agonist
DG01547 Fibrate
D01366 Bezafibrate
Drug classes [BR:br08332]
Cardiovascular agent
DG01946 Hypolipidemic agent
D01366 Bezafibrate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Thyroid hormone like receptors
Peroxisome proliferator-activated receptor (PPAR)
NR1C1 (PPARA)
D01366 Bezafibrate (JP18/USAN/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01366 Bezafibrate
D01366 Bezafibrate sustained release tablets
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| Other DBs |
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| KCF data |
ATOM 25
1 C8x C 20.0827 -19.2413
2 C8y C 20.0827 -20.6407
3 C8x C 21.2722 -21.3404
4 C8x C 22.5316 -20.6407
5 C8y C 22.5316 -19.2413
6 C8x C 21.2722 -18.5416
7 X Cl 18.8932 -21.3404
8 C5a C 23.7211 -18.5416
9 N1b N 24.9106 -19.2413
10 O5a O 23.7211 -17.1422
11 C1b C 26.1701 -18.5416
12 C1b C 27.3596 -19.2413
13 C8y C 28.5490 -18.5416
14 C8x C 29.8085 -19.2413
15 C8x C 30.9980 -18.5416
16 C8y C 30.9980 -17.1422
17 C8x C 29.8085 -16.4425
18 C8x C 28.5490 -17.1422
19 O2a O 32.1875 -16.4425
20 C1d C 33.4469 -17.1422
21 C6a C 34.6364 -16.4425
22 O6a O 35.8259 -17.1422
23 O6a O 34.6364 -15.0431
24 C1a C 32.7472 -18.3541
25 C1a C 34.1466 -18.3541
BOND 26
1 6 1 1
2 12 13 1
3 2 7 1
4 1 2 2
5 5 8 1
6 2 3 1
7 13 14 2
8 14 15 1
9 15 16 2
10 16 17 1
11 17 18 2
12 18 13 1
13 8 9 1
14 16 19 1
15 3 4 2
16 19 20 1
17 8 10 2
18 20 21 1
19 4 5 1
20 21 22 1
21 9 11 1
22 21 23 2
23 5 6 2
24 11 12 1
25 20 24 1
26 20 25 1
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