| Entry |
|
|---|
| Name |
Meperidine hydrochloride (USP);
Pethidine hydrochloride (JP18);
Demerol (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C15H21NO2. HCl
|
|---|
| Exact mass |
283.1339
|
|---|
| Mol weight |
283.7937
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
Analgesic
DG01984 Opioid analgesics
|
|---|
| Remark |
| Therapeutic category: | 8211 |
| Product (DG00816): | D01383<JP/US> |
| Product (mixture): | D03855<JP> |
|
|---|
| Efficacy |
Analgesic (narcotic), Antispasmodic, Opioid receptor agonist |
|---|
| Comment |
Phenylpiperidine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07224 | Opioid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N02 ANALGESICS
N02A OPIOIDS
N02AB Phenylpiperidine derivatives
N02AB02 Pethidine
D01383 Meperidine hydrochloride (USP) <JP/US>
USP drug classification [BR:br08302]
Analgesics
Opioid Analgesics, Short-acting
Meperidine
D01383 Meperidine hydrochloride (USP)
Therapeutic category of drugs in Japan [BR:br08301]
8 Narcotics
82 Non-alkaloidal narcotics
821 Synthetic narcotics
8211 Phenylpiperazines
D01383 Meperidine hydrochloride (USP); Pethidine hydrochloride (JP18)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG00816 Pethidine
D01383 Meperidine hydrochloride
Analgesic
DG01984 Opioid analgesics
DG00816 Pethidine
D01383 Meperidine hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D01383 Meperidine hydrochloride (USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01383 Pethidine hydrochloride
D01383 Pethidine hydrochloride for injection
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG00816 Pethidine
Analgesic
DG01984 Opioid analgesics
DG00816 Pethidine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 19
1 X Cl 28.2452 -17.0804
2 C8x C 21.1400 -14.4900
3 C8y C 21.1400 -15.8900
4 C8x C 22.3524 -16.5900
5 C8x C 23.5649 -15.8900
6 C8x C 23.5649 -14.4900
7 C8x C 22.3524 -13.7900
8 C1z C 19.9276 -16.5900
9 C1x C 18.7321 -15.8996
10 C1x C 17.5196 -16.5995
11 N1y N 17.5194 -17.9995
12 C1x C 18.7149 -18.6899
13 C1x C 19.9274 -17.9900
14 C1a C 16.2966 -18.7054
15 C7a C 20.6276 -17.8024
16 O7a O 22.0498 -17.8028
17 O6a O 19.9429 -18.9883
18 C1b C 22.7397 -18.9983
19 C1a C 24.1497 -18.9988
BOND 19
1 2 3 2
2 3 4 1
3 4 5 2
4 5 6 1
5 6 7 2
6 2 7 1
7 3 8 1
8 8 9 1
9 9 10 1
10 10 11 1
11 11 12 1
12 12 13 1
13 8 13 1
14 11 14 1
15 8 15 1
16 15 16 1
17 15 17 2
18 16 18 1
19 18 19 1
|
|---|
