| Entry |
|
|---|
| Name |
Ibudilast (JP18/INN);
Ketas (TN) |
|---|
| Formula |
C14H18N2O
|
|---|
| Exact mass |
230.1419
|
|---|
| Mol weight |
230.3055
|
|---|
| Structure |
|
|---|
| Class |
Cardiovascular agent
DG01507 Phosphodiesterase III inhibitor
Anti-allergic agent
DG01541 Cysteinyl leukotriene receptor antagonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiallergic, Bronchodilator, Vasodilator, Phosphodiesterase inhibitor, Leukotriene receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07228 | Eicosanoid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R03D OTHER SYSTEMIC DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R03DC Leukotriene receptor antagonists
R03DC04 Ibudilast
D01385 Ibudilast (JP18/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
13 Agents affecting sensory organs
131 Ophthalmic agents
1319 Others
D01385 Ibudilast (JP18/INN)
2 Agents affecting individual organs
21 Cardiovascular agents
219 Miscellaneous
2190 Miscellaneous
D01385 Ibudilast (JP18/INN)
4 Agents affecting cellular function
44 Allergic agents
449 Miscellaneous
4490 Miscellaneous
D01385 Ibudilast (JP18/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01507 Phosphodiesterase III inhibitor
D01385 Ibudilast
Anti-allergic agent
DG01541 Cysteinyl leukotriene receptor antagonist
D01385 Ibudilast
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Cysteinyl leukotriene
CYSLTR1
D01385 Ibudilast (JP18/INN) <JP>
Prostacyclin
PTGIR
D01385 Ibudilast (JP18/INN) <JP>
Enzymes
Hydrolases (EC3)
Phosphodiesterases
PDE3
D01385 Ibudilast (JP18/INN) <JP>
PDE4
D01385 Ibudilast (JP18/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01385 Ibudilast
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| Other DBs |
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| KCF data |
ATOM 17
1 C8y C 30.7566 -13.8910
2 C8x C 27.0075 -12.0480
3 C8x C 27.0075 -13.4486
4 C8x C 28.2235 -14.1489
5 C8x C 28.2235 -11.3477
6 N4y N 29.4322 -12.0480
7 C8y C 29.4263 -13.4520
8 C8y C 31.5895 -12.7592
9 N5x N 30.7693 -11.6199
10 C1c C 32.9902 -12.7663
11 C1a C 33.6842 -13.9831
12 C1a C 33.6968 -11.5570
13 C5a C 30.7566 -15.2910
14 O5a O 29.5382 -15.9946
15 C1c C 31.9358 -15.9713
16 C1a C 33.1409 -15.2749
17 C1a C 31.9362 -17.3599
BOND 18
1 1 8 1
2 8 9 2
3 9 6 1
4 6 5 1
5 8 10 1
6 5 2 2
7 2 3 1
8 3 4 2
9 4 7 1
10 6 7 1
11 10 11 1
12 7 1 2
13 10 12 1
14 1 13 1
15 13 14 2
16 13 15 1
17 15 16 1
18 15 17 1
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