| Entry |
|
|---|
| Name |
Ephedrine hydrochloride (JP18/USP);
Ephedrine hydrochloride (TN) |
|---|
| Product |
|
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| Formula |
C10H15NO. HCl
|
|---|
| Exact mass |
201.092
|
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| Mol weight |
201.6931
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Cardiovascular agent
DG01703 Cardiotonic
DG01702 Phenethylamine cardiotonic
DG01456 Adrenergic receptor agonist
Unclassified
DG03282 Ephedrine-containing preparation
|
|---|
| Remark |
| Product (DG00227): | D01386<JP/US> D04018<US> |
| Product (mixture): | D04338<JP> |
|
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| Efficacy |
Antitussive, Bronchodilator, Adrenergic receptor agonist |
|---|
| Comment |
Phenethylamine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
| hsa04270 | Vascular smooth muscle contraction |
|
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| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C01 CARDIAC THERAPY
C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
C01CA Adrenergic and dopaminergic agents
C01CA26 Ephedrine
D01386 Ephedrine hydrochloride (JP18/USP) <JP/US>
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AA Sympathomimetics, plain
R01AA03 Ephedrine
D01386 Ephedrine hydrochloride (JP18/USP) <JP/US>
R01AB Sympathomimetics, combinations excl. corticosteroids
R01AB05 Ephedrine
D01386 Ephedrine hydrochloride (JP18/USP) <JP/US>
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R03C ADRENERGICS FOR SYSTEMIC USE
R03CA Alpha- and beta-adrenoreceptor agonists
R03CA02 Ephedrine
D01386 Ephedrine hydrochloride (JP18/USP) <JP/US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01F MYDRIATICS AND CYCLOPLEGICS
S01FB Sympathomimetics excl. antiglaucoma preparations
S01FB02 Ephedrine
D01386 Ephedrine hydrochloride (JP18/USP) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
211 Cardiotonics
2118 Alkaloids
D01386 Ephedrine hydrochloride (JP18/USP)
22 Respiratory organ agents
222 Antitussives
2221 Ephedrines and Ephedra herbs
D01386 Ephedrine hydrochloride (JP18/USP)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Ephedrine
D01386 Ephedrine hydrochloride (JP18/USP)
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01702 Phenethylamine cardiotonic
DG00227 Ephedrine
D01386 Ephedrine hydrochloride
DG01456 Adrenergic receptor agonist
DG00227 Ephedrine
D01386 Ephedrine hydrochloride
Unclassified
DG03282 Ephedrine-containing preparation
DG00227 Ephedrine
D01386 Ephedrine hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D01386 Ephedrine hydrochloride (JP18/USP) <JP/US>
ADRA2
D01386 Ephedrine hydrochloride (JP18/USP) <JP/US>
ADRB
D01386 Ephedrine hydrochloride (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01386 Ephedrine hydrochloride
D01386 Ephedrine hydrochloride tablets
D01386 10% Ephedrine hydrochloride powder
D01386 Ephedrine hydrochloride injection
Rx-to-OTC switch list in the USA [br08315.html]
D01386
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01702 Phenethylamine cardiotonic
DG00227 Ephedrine
DG01456 Adrenergic receptor agonist
DG00227 Ephedrine
Unclassified
DG03282 Ephedrine-containing preparation
DG00227 Ephedrine
|
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| Other DBs |
|
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| KCF data |
ATOM 13
1 C8x C 17.0325 -17.0009
2 C8x C 17.0325 -18.4031
3 C8x C 18.2497 -19.1041
4 C8x C 19.4598 -18.4031
5 C8y C 19.4598 -17.0009
6 C8x C 18.2497 -16.2999
7 C1c C 20.6653 -16.2999
8 C1c C 21.8762 -16.9938
9 N1b N 23.0872 -16.2927
10 C1a C 24.2981 -16.9867
11 O1a O 20.6609 -14.8977
12 C1a C 21.8793 -18.3959
13 X Cl 29.1200 -17.5000
BOND 12
1 6 1 1
2 5 7 1
3 1 2 2
4 7 8 1
5 2 3 1
6 8 9 1
7 3 4 2
8 9 10 1
9 4 5 1
10 7 11 1 #Up
11 5 6 2
12 8 12 1 #Up
|
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