| Entry |
|
|---|
| Name |
Amcinonide (JAN/USP/INN);
Cyclocort (TN) |
|---|
| Product |
|
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| Generic |
|
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| Formula |
C28H35FO7
|
|---|
| Exact mass |
502.2367
|
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| Mol weight |
502.5717
|
|---|
| Structure |
|
|---|
| Simcomp |
|
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| Class |
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
Dermatological agent
DG03243 Atopic dermatitis agent
|
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| Remark |
| Therapeutic category: | 2646 |
|
|---|
| Efficacy |
Anti-inflammatory, Glucocorticoid receptor agonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
|
|---|
| Structure map |
| map07225 | Glucocorticoid and mineralocorticoid receptor agonists/antagonists |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AC Corticosteroids, potent (group III)
D07AC11 Amcinonide
D01387 Amcinonide (JAN/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Dermatological Agents
Dermatitis and Pruitus Agents
Glucocorticoids, High Potency
Amcinonide
D01387 Amcinonide (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
26 Epidermides
264 Analgesics, anti-itchings, astringents, anti-inflammatory agents
2646 Adrenocorticotropic hormones
D01387 Amcinonide (JAN/USP/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
D01387 Amcinonide
Dermatological agent
DG03243 Atopic dermatitis agent
D01387 Amcinonide
Drug classes [BR:br08332]
Anti-inflammatory
DG01955 Corticosteroid
D01387 Amcinonide
Dermatological agent
DG03243 Atopic dermatitis agent
D01387 Amcinonide
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D01387 Amcinonide (JAN/USP/INN) <JP/US>
Topical steroids potency [br08317.html]
Classification in the USA
D01387
Classification in Japan
D01387
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| Other DBs |
|
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| KCF data |
ATOM 36
1 C2x C 18.6900 -29.1900
2 C5x C 18.6900 -30.5200
3 C2x C 19.8800 -31.2200
4 C2y C 21.0700 -30.5200
5 C1z C 21.0700 -29.1900
6 C2x C 19.8800 -28.4900
7 C1x C 22.2600 -31.2200
8 C1x C 23.4500 -30.5200
9 C1y C 23.4500 -29.1900
10 C1z C 22.2600 -28.4900
11 C1y C 24.5000 -28.4900
12 C1z C 24.5000 -27.1600
13 C1x C 23.4500 -26.4600
14 C1y C 22.2600 -27.1600
15 C1x C 26.8800 -28.4900
16 C1y C 26.8800 -27.1600
17 C1z C 25.6900 -26.4600
18 O5x O 17.5700 -31.2200
19 C1a C 21.0700 -27.7900
20 X F 22.2600 -29.8200
21 O1a O 21.0700 -26.4600
22 C1a C 24.5000 -25.7600
23 C5a C 25.6900 -24.8500
24 O2x O 27.0900 -25.5500
25 O5a O 26.8800 -24.2200
26 C1b C 24.5000 -24.2200
27 O7a O 23.4500 -24.8500
28 O2x O 28.2800 -27.1600
29 C1z C 28.4900 -25.5500
30 C7a C 22.2600 -24.1500
31 C1a C 21.0700 -24.8500
32 O6a O 22.2600 -22.7500
33 C1x C 28.4900 -24.1500
34 C1x C 29.8200 -25.9700
35 C1x C 30.6600 -24.8500
36 C1x C 29.8200 -23.7300
BOND 41
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 2
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 9 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 10 14 1
17 11 15 1
18 15 16 1
19 16 17 1
20 12 17 1
21 2 18 2
22 5 19 1 #Up
23 10 20 1 #Down
24 14 21 1 #Up
25 12 22 1 #Up
26 17 23 1 #Up
27 17 24 1 #Down
28 23 25 2
29 23 26 1
30 26 27 1
31 16 28 1 #Down
32 24 29 1
33 29 28 1
34 27 30 1
35 30 31 1
36 30 32 2
37 33 29 1
38 29 34 1
39 34 35 1
40 35 36 1
41 33 36 1
|
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