| Entry |
|
|---|
| Name |
Mizoribine (JP18/INN);
Bredinin (TN) |
|---|
| Formula |
C9H13N3O6
|
|---|
| Exact mass |
259.0804
|
|---|
| Mol weight |
259.216
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Source |
Eupenicillium brefeldianum [TAX: 69794]
|
|---|
| Class |
Anti-inflammatory
DG01985 Disease modifying anti-rheumatic drug (DMARD)
|
|---|
| Remark |
| Therapeutic category: | 3999 |
|
|---|
| Efficacy |
Immunosuppressant, Inosine monophosphate synthetase inhibitor |
|---|
| Comment |
Ribofuranyl derivative
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07050 | Antirheumatics - DMARDs and biological agents |
|
|---|
| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
3 Agents affecting metabolism
39 Other agents affecting metabolism
399 Miscellaneous
3999 Others
D01392 Mizoribine (JP18/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01985 Disease modifying anti-rheumatic drug (DMARD)
D01392 Mizoribine
Drug classes [BR:br08332]
Antirheumatic agent
DG01985 Disease modifying anti-rheumatic drug (DMARD)
D01392 Mizoribine
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Dehydrogenases
IMPDH
D01392 Mizoribine (JP18/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01392 Mizoribine
D01392 Mizoribine tablets
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 18
1 C1y C 12.9500 -22.6100
2 C1y C 14.3500 -22.6100
3 C1y C 14.7700 -21.2800
4 O2x O 13.6500 -20.5100
5 C1y C 12.5300 -21.2800
6 N4y N 15.9600 -20.5800
7 C1b C 11.3400 -20.5800
8 O1a O 10.0800 -21.2800
9 O1a O 12.1100 -23.7300
10 O1a O 15.1900 -23.7300
11 C8y C 17.0800 -21.4200
12 C8y C 18.2000 -20.5800
13 N5x N 17.7800 -19.2500
14 C8x C 16.3800 -19.2500
15 O1a O 17.0800 -22.8200
16 C5a C 19.3900 -21.2800
17 N1a N 20.5800 -20.5800
18 O5a O 19.3900 -22.6800
BOND 19
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 1 5 1
6 3 6 1 #Up
7 5 7 1 #Up
8 7 8 1
9 1 9 1 #Down
10 2 10 1 #Down
11 6 11 1
12 11 12 2
13 12 13 1
14 13 14 2
15 6 14 1
16 11 15 1
17 12 16 1
18 16 17 1
19 16 18 2
|
|---|
