| Entry |
|
|---|
| Name |
Norfenefrine hydrochloride (JAN);
Zondel (TN) |
|---|
| Formula |
C8H11NO2. HCl
|
|---|
| Exact mass |
189.0557
|
|---|
| Mol weight |
189.6394
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01703 Cardiotonic
DG01702 Phenethylamine cardiotonic
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01448 alpha1-Adrenergic receptor agonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Cardiotonic |
|---|
| Comment |
Phenethylamine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C01 CARDIAC THERAPY
C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
C01CA Adrenergic and dopaminergic agents
C01CA05 Norfenefrine
D01405 Norfenefrine hydrochloride (JAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01702 Phenethylamine cardiotonic
DG00214 Norfenefrine
D01405 Norfenefrine hydrochloride
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01448 alpha1-Adrenergic receptor agonist
DG00214 Norfenefrine
D01405 Norfenefrine hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D01405 Norfenefrine hydrochloride (JAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01702 Phenethylamine cardiotonic
DG00214 Norfenefrine
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01448 alpha1-Adrenergic receptor agonist
DG00214 Norfenefrine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 12
1 X Cl 27.8780 -16.1264
2 C8y C 18.5500 -16.7300
3 C8x C 18.5500 -18.1300
4 C8x C 19.8100 -18.8300
5 C8x C 21.0000 -18.1300
6 C8y C 21.0000 -16.7300
7 C8x C 19.8100 -16.0300
8 C1c C 22.2600 -16.0300
9 C1b C 23.4500 -16.7300
10 O1a O 22.2600 -14.6300
11 N1a N 24.6400 -16.0300
12 O1a O 17.3600 -16.0300
BOND 11
1 2 3 2
2 3 4 1
3 4 5 2
4 5 6 1
5 6 7 2
6 2 7 1
7 6 8 1
8 8 9 1
9 8 10 1
10 9 11 1
11 2 12 1
|
|---|
