| Entry |
|
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| Name |
Cefotiam hexetil hydrochloride (JP18);
Pansporin-T (TN) |
|---|
| Formula |
C27H37N9O7S3. 2HCl
|
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| Exact mass |
767.1512
|
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| Mol weight |
768.7557
|
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| Structure |
|
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| Simcomp |
|
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| Class |
|
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| Remark |
| Product (DG00563): | D01819<JP> |
|
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| Efficacy |
Antibacterial, Cell wall biosynthesis inhibitor |
|---|
| Comment |
Active form of prodrug: Cefotiam [DR: D07648]
|
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| Target |
penicillin binding protein |
|---|
| Pathway |
|
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| Interaction |
|
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| Structure map |
| map07012 | Cephalosporins - parenteral agents |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01D OTHER BETA-LACTAM ANTIBACTERIALS
J01DC Second-generation cephalosporins
J01DC07 Cefotiam
D01415 Cefotiam hexetil hydrochloride (JP18)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00563 Cefotiam
D01415 Cefotiam hexetil hydrochloride
DG01775 Second-generation cephalosporin
DG00563 Cefotiam
D01415 Cefotiam hexetil hydrochloride
Antimicrobials [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Second-generation cephalosporin
D01415 Cefotiam hexetil hydrochloride (JP18)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01415 Cefotiam hexetil hydrochloride
Prodrugs [br08324.html]
D01415
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00563 Cefotiam
DG01775 Second-generation cephalosporin
DG00563 Cefotiam
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Second-generation cephalosporin
DG00563 Cefotiam
|
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| Other DBs |
|
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| KCF data |
ATOM 48
1 C1y C 26.1992 -13.1725
2 N1y N 26.1992 -14.5495
3 C2y C 27.3919 -15.2378
4 C2y C 28.5843 -14.5495
5 C1x C 28.5843 -13.1725
6 S2x S 27.3919 -12.4840
7 C1y C 24.8221 -13.1725
8 C5x C 24.8221 -14.5495
9 N1b N 23.6297 -12.4840
10 C5a C 22.4369 -13.1725
11 O5a O 22.4369 -14.5495
12 O5x O 23.6297 -15.2378
13 C1b C 21.2445 -12.4840
14 C1b C 29.7951 -15.2488
15 C8y C 20.0327 -13.1840
16 S2a S 30.9926 -14.5578
17 C8y C 32.1849 -15.2464
18 N5x N 32.5850 -16.6308
19 N5x N 33.9627 -16.6606
20 N5x N 34.4167 -15.2906
21 N4y N 33.3196 -14.4567
22 C8x C 18.8966 -12.3839
23 S2x S 17.7800 -13.2176
24 C8y C 18.2276 -14.5369
25 N5x N 19.6209 -14.5889
26 C1b C 33.3507 -13.0409
27 C1b C 34.5451 -12.3066
28 N1c N 35.7526 -12.9597
29 C1a C 36.9049 -12.2509
30 C1a C 35.7924 -14.3526
31 N1a N 17.3885 -15.6630
32 C7a C 27.3919 -17.4647
33 O6a O 26.1934 -18.1567
34 O7a O 28.5974 -18.1608
35 C1c C 28.5974 -19.5488
36 C1a C 27.3806 -20.2515
37 O7a O 29.7827 -20.2333
38 C7a C 30.9616 -19.5525
39 O7a O 32.1418 -20.2341
40 C1y C 33.3213 -19.5530
41 O6a O 30.9617 -18.1589
42 C1x C 34.5013 -20.2343
43 C1x C 35.7033 -19.5403
44 C1x C 35.7034 -18.1523
45 C1x C 34.5234 -17.4711
46 C1x C 33.3214 -18.1650
47 X Cl 20.8705 -19.0297
48 X Cl 20.8705 -19.0297
BOND 50
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 1
7 1 7 1
8 7 8 1
9 2 8 1
10 7 9 1 #Up
11 9 10 1
12 10 11 2
13 8 12 2
14 10 13 1
15 4 14 1
16 13 15 1
17 14 16 1
18 16 17 1
19 17 18 2
20 18 19 1
21 19 20 2
22 20 21 1
23 17 21 1
24 15 22 2
25 22 23 1
26 23 24 1
27 24 25 2
28 15 25 1
29 21 26 1
30 26 27 1
31 27 28 1
32 28 29 1
33 28 30 1
34 24 31 1
35 3 32 1
36 32 33 2
37 32 34 1
38 34 35 1
39 35 36 1
40 35 37 1
41 37 38 1
42 38 39 1
43 39 40 1
44 38 41 2
45 40 42 1
46 42 43 1
47 43 44 1
48 44 45 1
49 45 46 1
50 40 46 1
BRACKET 1 19.1800 -19.7400 19.1800 -18.3400
1 21.5600 -18.3400 21.5600 -19.7400
1 2
ORIGINAL 1 48
REPEAT 1 49
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